Are storage phosphors a useful tool for soft x-ray imaging diagnostics? Spectral sensitivity and spatial resolution in the 0.07 to 14 nm range

1998 ◽  
Vol 83 (4) ◽  
pp. 2276-2281 ◽  
Author(s):  
B. Nensel ◽  
P. Thielemann ◽  
G. Decker
2021 ◽  
Vol 20 ◽  
pp. 153303382110101
Author(s):  
Thet-Thet Lwin ◽  
Akio Yoneyama ◽  
Hiroko Maruyama ◽  
Tohoru Takeda

Phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer provides high sensitivity and high spatial resolution, and it has the ability to depict the fine morphological structures of biological soft tissues, including tumors. In this study, we quantitatively compared phase-contrast synchrotron-based X-ray computed tomography images and images of histopathological hematoxylin-eosin-stained sections of spontaneously occurring rat testicular tumors that contained different types of cells. The absolute densities measured on the phase-contrast synchrotron-based X-ray computed tomography images correlated well with the densities of the nuclear chromatin in the histological images, thereby demonstrating the ability of phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer to reliably identify the characteristics of cancer cells within solid soft tissue tumors. In addition, 3-dimensional synchrotron-based phase-contrast X-ray computed tomography enables screening for different structures within tumors, such as solid, cystic, and fibrous tissues, and blood clots, from any direction and with a spatial resolution down to 26 μm. Thus, phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer shows potential for being useful in preclinical cancer research by providing the ability to depict the characteristics of tumor cells and by offering 3-dimensional information capabilities.


Nanomaterials ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1721
Author(s):  
Heon Yong Jeong ◽  
Hyung San Lim ◽  
Ju Hyuk Lee ◽  
Jun Heo ◽  
Hyun Nam Kim ◽  
...  

The effect of scintillator particle size on high-resolution X-ray imaging was studied using zinc tungstate (ZnWO4) particles. The ZnWO4 particles were fabricated through a solid-state reaction between zinc oxide and tungsten oxide at various temperatures, producing particles with average sizes of 176.4 nm, 626.7 nm, and 2.127 μm; the zinc oxide and tungsten oxide were created using anodization. The spatial resolutions of high-resolution X-ray images, obtained from utilizing the fabricated particles, were determined: particles with the average size of 176.4 nm produced the highest spatial resolution. The results demonstrate that high spatial resolution can be obtained from ZnWO4 nanoparticle scintillators that minimize optical diffusion by having a particle size that is smaller than the emission wavelength.


2014 ◽  
Vol 62 ◽  
pp. 28-34 ◽  
Author(s):  
A. Cecilia ◽  
V. Jary ◽  
M. Nikl ◽  
E. Mihokova ◽  
D. Hänschke ◽  
...  

2005 ◽  
Author(s):  
Michael R. Squillante ◽  
Richard A. Myers ◽  
Mitchell Woodring ◽  
James F. Christian ◽  
Frank Robertson ◽  
...  

2004 ◽  
Vol 33 (4) ◽  
pp. 206-208
Author(s):  
V. F. Dvoryankin ◽  
Yu. M. Dikaev ◽  
A. I. Krikunov ◽  
T. M. Panova ◽  
A. A. Telegin

2021 ◽  
Author(s):  
James Day

To further develop a MV x-ray portal imaging device with high detection efficiency and adequate spatial resolution for image guided radiation therapy, the experimental results for a prototype detector were matched using Monte-Carlo software to then improve upon the design. The simulation and experiment were carried out using a 6 MV beam from a linear accelerator machine. An adequate match was obtained with the spatial resolution matching up to a MTF value of 0.2 and then diverging and the total signal registered in the central fiber was matched for field sizes ranging from 3 cm by 3 cm to 20 cm by 20 cm for 5 cm, 15 cm and 25 cm air gaps within 3%. The design was altered from a hexagonal array of round double cladded fibers to a square array of single cladded square fibers. The spatial resolution was improved from 0.242 lp mm-1 to 0.359 lp mm-1 at an MTF value of 0.5 from the original design to a square array of square fibers 0.5 mm wide separated by 0.25 mm of lead foil. With further optimization of the detector design it may be possible to increase spatial resolution for MV x-ray imaging while maintaining an adequate detection efficiency.


2008 ◽  
Vol 16 (6) ◽  
pp. 14-17 ◽  
Author(s):  
Paul Mainwaring

X-ray ultramicroscopy in the SEM is a relatively new application in the wider field of X-ray microscopy. This latter field includes synchrotron and cabinet-based systems that vary in their X-ray power, capability, sample size, spatial resolution, and convenience. One important capability of the SEM-hosted X-ray microscope is that the normal SEM imaging and analytical functions such as secondary and backscattered imaging and microanalysis by EDX or WDS are unimpeded. X-ray imaging then serves as a complement to the normal use of the SEM. The convenience of easy access in an SEM lab to an X-ray microscope with 3D tomographic capability makes this an important development.


2014 ◽  
Vol 12 (9) ◽  
pp. 093401-93405 ◽  
Author(s):  
Shengzhen Yi Shengzhen Yi ◽  
Baozhong Mu Baozhong Mu ◽  
Xin Wang Xin Wang ◽  
Li Jiang Li Jiang ◽  
Jingtao Zhu Jingtao Zhu ◽  
...  

Author(s):  
Timur Gureyev ◽  
David M. Paganin ◽  
Alex Kozlov ◽  
Harry Quiney

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