Confocal volume in laser Raman microscopy depth profiling

2011 ◽  
Vol 110 (10) ◽  
pp. 103107 ◽  
Author(s):  
Yutaka Maruyama ◽  
Wataru Kanematsu
2018 ◽  
Vol 91 (1) ◽  
pp. 1049-1055 ◽  
Author(s):  
Carol Korzeniewski ◽  
Jay P. Kitt ◽  
Saheed Bukola ◽  
Stephen E. Creager ◽  
Shelley D. Minteer ◽  
...  

2005 ◽  
Vol 59 (2) ◽  
pp. 200-205 ◽  
Author(s):  
P. Matousek ◽  
N. Everall ◽  
M. Towrie ◽  
A. W. Parker

We demonstrate how pulsed laser Raman excitation (∼1 ps) followed by fast optical Kerr gating (∼4 ps) can be used to effectively separate Raman signals originating from different depths in heterogeneous diffusely scattering media. The diffuse scattering slows down photon propagation through turbid samples enabling higher depth resolution than would be obtained for a given instrumental time resolution in an optically transparent medium. Two types of experiments on two-layer systems demonstrate the ability to differentiate between surface and sub-surface Raman signals. A Raman spectrum was obtained of stilbene powder buried beneath a 1 mm over-layer of PMMA (poly(methyl methacrylate)) powder. The signal contrasts of the lower stilbene layer and upper PMMA layer were improved by factors ≥5 and ≥180, respectively, by rejecting the Raman component of the counterpart layer. The ability to select the Raman signal of a thin top surface layer in preference to those from an underlying diffusely scattering substrate was demonstrated using a 100 μm thick optically transparent film of PET (poly(ethylene terephthalate)) on top of stilbene powder. The gating resulted in the suppression of the underlying stilbene Raman signal by a factor of 1200. The experiments were performed in back-scattering geometry using 400 nm excitation wavelength. The experimental technique should be well suited to biomedical applications such as disease diagnosis.


2012 ◽  
Vol 616-618 ◽  
pp. 715-719
Author(s):  
Ming Ming Tang ◽  
Jin Liang Zhang

Hydrocarbon detection while drilling (HDWD) is important for obtain proper drilling performance. In this report, Raman spectra for hydrocarbon in returned water based drilling fluid have been acquired using He-Ne laser (633nm) excitation. The relative intensities of several Raman bands are found to depend on the concentration of hydrocarbon in returned drilling fluid. Spectra are interpreted as indicating that Raman spectra could be used as potential method for HDWD.


Author(s):  
J. Sacristán ◽  
H. Reinecke ◽  
C. Mijangos ◽  
S. Spells ◽  
J. Yarwood

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