Optical Trapping Raman Spectroscopy Of Protein and Membrane Interaction

2010 ◽  
Author(s):  
Anjan Roy ◽  
Marcelo Nakaema ◽  
Timothy A. Keiderling ◽  
P. M. Champion ◽  
L. D. Ziegler
Keyword(s):  
Raman Spectroscopy ◽  
Optical Trapping ◽  
Membrane Interaction

scholarly journals Optical Trapping Raman Spectroscopy of Protein and Membrane Interaction

2011 ◽  
Vol 100 (3) ◽  
pp. 314a
Author(s):  
Anjan Roy ◽  
Marcelo Nakaema ◽  
Timothy A. Keiderling
Keyword(s):  
Raman Spectroscopy ◽  
Optical Trapping ◽  
Membrane Interaction

Investigations of multiple component systems by means of optical trapping and Raman spectroscopy

1995 ◽  
Vol 348 ◽  
pp. 265-268 ◽  
Author(s):  
M. Lankers ◽  
J. Popp ◽  
E. Urlaub ◽  
H. Stahl ◽  
G. Rößling ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Trapping ◽  
Component Systems ◽  
Multiple Component

scholarly journals On-chip optical trapping and Raman spectroscopy using a TripleX dual-waveguide trap

2014 ◽  
Vol 22 (25) ◽  
pp. 30528 ◽  
Author(s):  
Martijn Boerkamp ◽  
Thijs van Leest ◽  
Jeroen Heldens ◽  
Arne Leinse ◽  
Marcel Hoekman ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Trapping ◽  
On Chip

Optofluidic Chips for Raman Spectroscopy and Optical Trapping

2017 ◽  
Author(s):  
Heidi Ottevaere ◽  
Qing Liu ◽  
Diane de Coster ◽  
Jürgen Van Erps ◽  
Michael Vervaeke ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Trapping

scholarly journals Integrated photonics multi-waveguide devices for optical trapping and Raman spectroscopy: design, fabrication and performance demonstration

2020 ◽  
Vol 11 ◽  
pp. 829-842 ◽  
Author(s):  
Gyllion B Loozen ◽  
Arnica Karuna ◽  
Mohammad M R Fanood ◽  
Erik Schreuder ◽  
Jacob Caro
Keyword(s):  
Raman Spectroscopy ◽  
Optical Trapping ◽  
Integrated Photonics ◽  
Trapping Region ◽  
Waveguide Devices ◽  
Multiple Beams ◽  
Wide Range ◽  
And Performance ◽  
Performance Demonstration ◽  
Waveguide Device

We realized integrated photonics multi-waveguide devices for optical trapping and Raman spectroscopy of particles in a fluid. In these devices, multiple beams directed towards the device center lead to a local field enhancement around this center and thus counteract the effect of light concentration near the facets, which is a disadvantage of dual-waveguide traps. Thus, a trapping region is created around the center, where a single particle of a size in a wide range can be trapped and studied spectroscopically, free from the influence of surfaces. We report the design (including simulations), fabrication and performance demonstration for multi-waveguide devices, using our Si3N4 waveguiding platform as the basis. The designed ridge waveguides, optimized for trapping and Raman spectroscopy, emit narrow beams. Multiple waveguides arranged around the central microbath result from fanning out of a single input waveguide using Y-splitters. A second waveguiding layer is implemented for detection of light scattered by the trapped particle. For reliable filling of the device with sample fluid, microfluidic considerations lead to side channels of the microbath, to exploit capillary forces. The interference of the multiple beams produces an array of hot spots around the bath center, each forming a local trap. This property is clearly confirmed in the experiments and is registered in videos. We demonstrate the performance of a 2-waveguide and a 16-waveguide device, using 1 and 3 μm polystyrene beads. Study of the confined Brownian motion of the trapped beads yields experimental values of the normalized trap stiffness for the in-plane directions. The stiffness values for the 16-waveguide device are comparable to those of tightly focused Gaussian beam traps and are confirmed by our own simulations. The Raman spectra of the beads (in this work measured via an objective) show clear peaks that are characteristic of polystyrene. In the low-wavenumber range, the spectra have a background that most likely originates from the Si3N4 waveguides.

Optical Trapping Raman Spectroscopy As a Sensor / Actuator / Treatment System

2020 ◽  
Vol MA2020-02 (66) ◽  
pp. 3325-3325
Author(s):  
Morten Bertz ◽  
Denise Molinnus ◽  
Michael J. Schoening ◽  
Takayuki Homma
Keyword(s):  
Raman Spectroscopy ◽  
Optical Trapping ◽  
Treatment System ◽  
Sensor Actuator
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