Hybrid quantitative simulation on the in-line phase-contrast x-ray imaging of three dimensional samples under actual clinic imaging parameters

2009 ◽  
Vol 95 (1) ◽  
pp. 011111 ◽  
Author(s):  
Hong Yu ◽  
Shensheng Han ◽  
Jianhui Ding ◽  
Zhaoxia Jiang ◽  
Weijun Peng
Keyword(s):  
Phase Contrast ◽  
Three Dimensional ◽  
X Ray ◽  
Imaging Parameters ◽  
X Ray Imaging

Measurements of imaging parameters of a phase contrast x-ray imaging prototype

2008 ◽  
Author(s):  
Yuhua Li ◽  
John Rong ◽  
Robert Y. L. Chu ◽  
Da Zhang ◽  
Ann Archer ◽  
...  
Keyword(s):  
Phase Contrast ◽  
X Ray ◽  
Imaging Parameters ◽  
X Ray Imaging

X-Ray Phase-Contrast Tomography for Quantitative Characterisation of Self-Healing Polymers

2010 ◽  
Vol 654-656 ◽  
pp. 2322-2325 ◽  
Author(s):  
Sheridan Mayo ◽  
Andrew Stevenson ◽  
Stephen Wilkins ◽  
Da Chao Gao ◽  
Steven Mookhoek ◽  
...  
Keyword(s):  
Phase Contrast ◽  
Three Dimensional ◽  
Polymer System ◽  
Self Healing ◽  
Contrast Imaging ◽  
X Ray ◽  
X Ray Imaging ◽  
Quantitative Characterisation ◽  
Micro Tomography ◽  
Phase Contrast Tomography

X-ray phase-contrast imaging and tomography add an additional dimension to conventional x-ray methods by exploiting the x-ray refraction effects in addition to x-ray absorption in forming an image. This greatly enhances the visibility of edges, voids and boundaries within a sample. It also makes it possible to characterise weakly x-ray absorbing samples which would produce little or no contrast in conventional x-ray imaging. Here we described the application of a laboratory-based x-ray phase-contrast microscope to x-ray micro-tomography of a self-healing polymer system and the quantitative analysis of the resulting three dimensional (3D) datasets to better understand the healing and ageing processes.

Computer simulations of X-ray phase-contrast images and microtomographic observation of tubules in dentin

2020 ◽  
Vol 27 (2) ◽  
pp. 462-467
Author(s):  
T. S. Argunova ◽  
V. G. Kohn ◽  
J.-H. Lim ◽  
Z. V. Gudkina ◽  
E. D. Nazarova
Keyword(s):  
Phase Contrast ◽  
Three Dimensional ◽  
Phase Contrast Imaging ◽  
Contrast Imaging ◽  
Dentinal Tubules ◽  
X Ray ◽  
Coherent Synchrotron Radiation ◽  
X Ray Imaging ◽  
Section Structure ◽  
Comparative Examination

An investigation of the problems of X-ray imaging of dentinal tubules is presented. Two main points are addressed. In the first part of this paper, the problem of computer simulating tubule images recorded in a coherent synchrotron radiation (SR) beam has been discussed. A phantom material which involved a two-dimensional lattice of the tubules with parameters similar to those of dentin was considered. By a comparative examination of two approximations, it was found that the method of phase-contrast imaging is valid if the number of tubules along the beam is less than 100. Calculated images from a lattice of 50 × 50 tubules are periodic in free space but depend strongly on the distance between the specimen and the detector. In the second part, SR microtomographic experiments with millimetre-sized dentin samples in a partially coherent beam have been described. Tomograms were reconstructed from experimental projections using a technique for incoherent radiation. The main result of this part is the three-dimensional rendering of the directions of the tubules in a volume of the samples. Generation of the directions is possible because a tomogram shows the positions of the tubules. However, a detailed tubule cross-section structure cannot be restored.

Non-destructive phase contrast hard x-ray imaging to reveal the three-dimensional microstructure of soft and hard tissues

2016 ◽  
Author(s):  
Anna Khimchenko ◽  
Georg Schulz ◽  
Hans Deyhle ◽  
Simone E. Hieber ◽  
Samiul Hasan ◽  
...  
Keyword(s):  
Phase Contrast ◽  
Three Dimensional ◽  
X Ray ◽  
X Ray Imaging ◽  
Hard Tissues ◽  
Non Destructive

scholarly journals Principles of Different X-ray Phase-Contrast Imaging: A Review

2021 ◽  
Vol 11 (7) ◽  
pp. 2971
Author(s):  
Siwei Tao ◽  
Congxiao He ◽  
Xiang Hao ◽  
Cuifang Kuang ◽  
Xu Liu
Keyword(s):  
Biological Samples ◽  
Phase Contrast ◽  
Recent Progress ◽  
Phase Contrast Imaging ◽  
Contrast Imaging ◽  
X Ray ◽  
X Ray Imaging ◽  
Internal Structures ◽  
X Ray Absorption ◽  
Made In

Numerous advances have been made in X-ray technology in recent years. X-ray imaging plays an important role in the nondestructive exploration of the internal structures of objects. However, the contrast of X-ray absorption images remains low, especially for materials with low atomic numbers, such as biological samples. X-ray phase-contrast images have an intrinsically higher contrast than absorption images. In this review, the principles, milestones, and recent progress of X-ray phase-contrast imaging methods are demonstrated. In addition, prospective applications are presented.

scholarly journals Visualization Ability of Phase-Contrast Synchrotron-Based X-Ray Imaging Using an X-Ray Interferometer in Soft Tissue Tumors

2021 ◽  
Vol 20 ◽  
pp. 153303382110101
Author(s):  
Thet-Thet Lwin ◽  
Akio Yoneyama ◽  
Hiroko Maruyama ◽  
Tohoru Takeda
Keyword(s):  
Computed Tomography ◽  
Soft Tissue ◽  
Spatial Resolution ◽  
Phase Contrast ◽  
Soft Tissue Tumors ◽  
X Ray ◽  
3 Dimensional ◽  
Computed Tomography Images ◽  
X Ray Imaging ◽  
X Ray Computed

Phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer provides high sensitivity and high spatial resolution, and it has the ability to depict the fine morphological structures of biological soft tissues, including tumors. In this study, we quantitatively compared phase-contrast synchrotron-based X-ray computed tomography images and images of histopathological hematoxylin-eosin-stained sections of spontaneously occurring rat testicular tumors that contained different types of cells. The absolute densities measured on the phase-contrast synchrotron-based X-ray computed tomography images correlated well with the densities of the nuclear chromatin in the histological images, thereby demonstrating the ability of phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer to reliably identify the characteristics of cancer cells within solid soft tissue tumors. In addition, 3-dimensional synchrotron-based phase-contrast X-ray computed tomography enables screening for different structures within tumors, such as solid, cystic, and fibrous tissues, and blood clots, from any direction and with a spatial resolution down to 26 μm. Thus, phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer shows potential for being useful in preclinical cancer research by providing the ability to depict the characteristics of tumor cells and by offering 3-dimensional information capabilities.

A Microfocal Method for Phase-Contrast X-Ray Imaging

2009 ◽  
Vol 43 (4) ◽  
pp. 156-160
Author(s):  
N. N. Blinov ◽  
A. Yu. Vasil’ev ◽  
N. S. Serova ◽  
A. Yu. Gryaznov ◽  
N. N. Potrakhov
Keyword(s):  
Phase Contrast ◽  
X Ray ◽  
X Ray Imaging

X-ray imaging with ultra-small-angle X-ray scattering as a contrast mechanism

2004 ◽  
Vol 37 (5) ◽  
pp. 757-765 ◽  
Author(s):  
L. E. Levine ◽  
G. G. Long
Keyword(s):  
Small Angle ◽  
Imaging Technique ◽  
Three Dimensional ◽  
Sample Volume ◽  
Contrast Imaging ◽  
X Ray ◽  
X Ray Scattering ◽  
X Ray Imaging ◽  
Contrast Mechanism ◽  
Ray Scattering

A new transmission X-ray imaging technique using ultra-small-angle X-ray scattering (USAXS) as a contrast mechanism is described. USAXS imaging can sometimes provide contrast in cases where radiography and phase-contrast imaging are unsuccessful. Images produced at different scattering vectors highlight different microstructural features within the same sample volume. When used in conjunction with USAXS scans, USAXS imaging provides substantial quantitative and qualitative three-dimensional information on the sizes, shapes and spatial arrangements of the scattering objects. The imaging technique is demonstrated on metal and biological samples.

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