Determination of Radiation Energy Response for Thermoluminescent Dosimeter TLD-100: Determination of Organ Dose in Diagnostic Radiology (abstract)

2009 ◽  
Author(s):  
Antoneta Deda ◽  
Ervis Telhaj ◽  
Beverly Karplus Hartline ◽  
Renee K. Horton ◽  
Catherine M. Kaicher
Keyword(s):  
Radiation Energy ◽  
Organ Dose ◽  
Diagnostic Radiology ◽  
Energy Response ◽  
Thermoluminescent Dosimeter

scholarly journals Investigation of TLD-700 energy response to low energy x-ray encountered in diagnostic radiology

Open Physics ◽  
2016 ◽  
Vol 14 (1) ◽  
pp. 150-158
Author(s):  
Ammar Herrati ◽  
Mourad Bourouina ◽  
Karima Khalal-Kouache
Keyword(s):  
Good Accuracy ◽  
Low Energy ◽  
Diagnostic Radiology ◽  
Maximum Deviation ◽  
Energy Response ◽  
Radiation Quality ◽  
X Ray ◽  
Thermoluminescent Dosimeter ◽  
Entrance Dose ◽  
Better Than

AbstractThe aim of thiswork is to study the energy dependence of thermoluminescent dosimeter (TLD-700) for low energy X-ray beams encountered in conventional diagnostic radiology. In the first step, we studied some characteristics (reproducibility and linearity) of TLD-700 chips using a 137Cs source, and selected TLD chips with reproducibility better than 2.5%. Then we determined TLD-700 energy response for diagnostic radiology X-ray qualities, and investigated its influence on air kerma estimate. A maximum deviation of 60% can be obtained if TLDs are calibrated for 137Cs radiation source and used in diagnostic radiology fields. However, this deviation became less than 20% if TLDs chips are calibrated for the reference x-ray radiation quality RQR5 (recommended by the IEC 61267 standard). Consequently, we recommend calibrating this kind of TLDdetector with RQR5 diagnostic radiology X-ray quality. This method permits to obtain a good accuracy when assessing the entrance dose in diagnostic radiology procedures.

scholarly journals Size determination of an equilibrium enzymic system by radiation inactivation: theoretical considerations

1982 ◽  
Vol 205 (3) ◽  
pp. 477-483 ◽  
Author(s):  
P Simon ◽  
S Swillens ◽  
J E Dumont
Keyword(s):  
Enzyme Activity ◽  
Numerical Data ◽  
Radiation Energy ◽  
Target Size ◽  
Molecular Organization ◽  
Size Analysis ◽  
Radiation Inactivation ◽  
Theoretical Considerations ◽  
Regulation Of Enzyme Activity

Radiation inactivation of complex enzymic systems is currently used to determine the enzyme size and the molecular organization of the components in the system. We have simulated an equilibrium model describing the regulation of enzyme activity by association of the enzyme with a regulatory unit. It is assumed that, after irradiation, the system equilibrates before the enzyme activity is assayed. Our theoretical results show that the target-size analysis of these numerical data leads to a bad estimate of the enzyme size. Moreover, some implicit assumptions such as the transfer of radiation energy between non-covalently bound molecules should be verified before interpretation of target-size analysis. It is demonstrated that the apparent target size depends on the parameters of the system, namely the size and the concentration of the components, the equilibrium constant, the relative activities of free enzyme and enzymic complex, the existence of energy transfer, and the distribution of the components between free and bound forms during the irradiation.

scholarly journals PV-0287: Determination of MC-based predictive models for personalized and fast kV-CBCT organ dose estimation

2017 ◽  
Vol 123 ◽  
pp. S151
Author(s):  
H. Chesneau ◽  
M. Vangvichith ◽  
E. Barat ◽  
C. Lafond ◽  
D. Lazaro-Ponthus
Keyword(s):  
Predictive Models ◽  
Organ Dose ◽  
Dose Estimation

Physical aspects of scintigraphybased dosimetry for nuclear medicine therapy

2010 ◽  
Vol 49 (03) ◽  
pp. 85-95 ◽  
Author(s):  
A. Schaefer ◽  
B. O. Knoop ◽  
J. Pinkert ◽  
M. Plotkin ◽  
C. M. Kirsch ◽  
...  
Keyword(s):  
Nuclear Medicine ◽  
Radiation Dose ◽  
Organ Dose ◽  
Whole Body ◽  
Whole Body Imaging ◽  
Body Imaging ◽  
Scintigraphic Imaging ◽  
Efficient Delivery ◽  
Procedural Recommendations

SummaryIn nuclear medicine therapy the treatment of tumours by radiation exposure from internally deposited labelled antibodies or labelled peptides is currently an active field of investigation. To permit the efficient delivery of high amounts of radiation dose to tumours while limiting the radiation dose to critical organs dosimetry calculations have to be performed. These are relying on scintigraphic data being input to the well known MIRD formalism.This paper focuses on the methods and the difficulties associated with the scintigraphic determination of organ kinetics. The physical properties of the well-known scintigraphic imaging modalities, PET, SPECT and planar scintigraphy, are discussed thereby taking into account the properties of the appropriate radionuclides currently being available for therapy and dosimetry. Several arguments are given and disputed for the limited clinical use of PET and SPECT in dosimetry and the ongoing preference of planar whole-body imaging as the method of choice. The quantitative restrictions still inherent to this method are also discussed in detail. Procedural recommendations are proposed covering all processes related to data acquisition, data correction and data analysis which finally lead to reliable estimations of organ dose.

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