A microfluidic Coulter counting device for metal wear detection in lubrication oil

2009 ◽  
Vol 80 (1) ◽  
pp. 016105 ◽  
Author(s):  
Srinidhi Murali ◽  
Ashish V. Jagtiani ◽  
Xingao Xia ◽  
Joan Carletta ◽  
Jiang Zhe
Keyword(s):  
Metal Wear ◽  
Lubrication Oil ◽  
Counting Device ◽  
Coulter Counting

A Magnetic Coulter Counting Device for Wear Debris Detection in Lubrication

2009 ◽  
Author(s):  
Li Du ◽  
Joan Carletta ◽  
Robert Veillette ◽  
Jiang Zhe
Keyword(s):  
Wear Debris ◽  
Online Monitoring ◽  
Ferrous Metal ◽  
Metal Particles ◽  
Aluminum Particles ◽  
Debris Particles ◽  
Planar Coil ◽  
Lubrication Oil ◽  
Counting Device ◽  
Coulter Counting

A device based on a magnetic Coulter counting principle to detect metal particles in lubrication oil is presented. The device detects the passage of ferrous and non ferrous particles by monitoring inductance change in a coil. First, the sensing principle is demonstrated at the mesoscale using a solenoid. Next, a microscale device is developed using a planar coil. The device is tested using iron and aluminum particles ranging from 100μm to 500μm. The testing results show the device is capable of detecting and distinguishing ferrous and non-ferrous metal particles in lubrication oil. The design concept demonstrated here can be extended to a microfluidic device for online monitoring of ferrous and non-ferrous wear debris particles.

Real-time monitoring of wear debris in lubrication oil using a microfluidic inductive Coulter counting device

2010 ◽  
Vol 9 (6) ◽  
pp. 1241-1245 ◽  
Author(s):  
Li Du ◽  
Jiang Zhe ◽  
Joan Carletta ◽  
Robert Veillette ◽  
Fred Choy
Keyword(s):  
Real Time ◽  
Wear Debris ◽  
Real Time Monitoring ◽  
Lubrication Oil ◽  
Counting Device ◽  
Coulter Counting

Capacitive Coulter counting: detection of metal wear particles in lubricant using a microfluidic device

2009 ◽  
Vol 18 (3) ◽  
pp. 037001 ◽  
Author(s):  
Srinidhi Murali ◽  
Xingao Xia ◽  
Ashish V Jagtiani ◽  
Joan Carletta ◽  
Jiang Zhe
Keyword(s):  
Microfluidic Device ◽  
Wear Particles ◽  
Metal Wear ◽  
Coulter Counting ◽  
Metal Wear Particles

scholarly journals Chromium and cobalt intoxication mimicking mitochondriopathy

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Tim W. Rattay ◽  
Torsten Kluba ◽  
Ludger Schöls
Keyword(s):  
Diabetes Mellitus ◽  
Weight Loss ◽  
Mitochondrial Dna ◽  
Wear Debris ◽  
Hip Prosthesis ◽  
Mitochondrial Cytopathy ◽  
Whole Exome ◽  
Metal On Metal ◽  
Metal Wear ◽  
History Of

AbstractA 53-year old male with a history of progressive visual impairment, hearing loss, peripheral neuropathy, poorly controlled diabetes mellitus, cardiomyopathy, and weight loss was referred to the rare disease center due to the suspicion of mitochondrial cytopathy. In line with mitochondrial dysfunction, lactate in CSF was increased. Genetic testing by whole-exome sequencing and mitochondrial DNA did not reveal a likely cause. The case remained unsolved until he developed pain in his right hip, where he had received total hip arthroplasty 12 years earlier. An orthopedic evaluation revealed substantial shrinkage of the head of the hip prosthesis. Due to metal-on-metal wear, debris chromium and cobalt levels in serum were massively increased and significantly improved with multisystemic impairment after exchanging the defective implant.

scholarly journals Digital Cell Counting Device Integrated with a Single-Cell Array

PLoS ONE ◽  
2014 ◽  
Vol 9 (2) ◽  
pp. e89011 ◽  
Author(s):  
Tatsuya Saeki ◽  
Masahito Hosokawa ◽  
Tae-kyu Lim ◽  
Manabu Harada ◽  
Tadashi Matsunaga ◽  
...  
Keyword(s):  
Single Cell ◽  
Cell Counting ◽  
Cell Array ◽  
Counting Device

scholarly journals Suitability of a Progenitor Cell-Enriching Device for In Vitro Applications

Coatings ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 146
Author(s):  
Antonio Celentano ◽  
Tami Yap ◽  
Giuseppe Pantaleo ◽  
Rita Paolini ◽  
Michael McCullough ◽  
...  
Keyword(s):  
Cell Viability ◽  
Time Course ◽  
Ex Vivo ◽  
Trypan Blue Exclusion ◽  
Trypan Blue Exclusion Test ◽  
Initial Reduction ◽  
Metal Wear ◽  
Class 1 ◽  
Electron Energy Loss

Rigenera® is a novel class-1 medical device that produces micro-grafts enriched of progenitors cells without ex vivo manipulation of donor tissues. The manufacturer’s protocol has been supported for a wide variety of clinical uses in the field of regenerative medicine. This study aimed to evaluate its potential use for in vitro cell models. Human primary oral fibroblasts were cultured under standard conditions and processed through Rigenera® over a time course of up to 5 min. Cell viability was assessed using a Trypan Blue exclusion test. It is possible to process fibroblasts through Rigenera® although an initial reduction of cell viability was observed. Additionally, debris was evident in the cell suspension of the processed samples. Scanning electron microscopy (SEM) microanalysis of the debris and electron energy-loss spectroscopy confirmed the presence of metal wear possibly due to the processing conditions used in this study. Interestingly, pore sizes within Rigeneracons® grids were found to range between 250–400 μm. This is the first report assessing the suitability of Rigenera® and Rigeneracons® for in vitro applications. Whilst Rigenera® workflow was found to be amenable to laboratory uses, our results strongly suggest that further research and development is necessary to support the utilization of this technology for enrichment of micro-graft derived cells and cell sorting in vitro.

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