Alloying strongly influences the structure, dynamics, and glass forming ability of metallic supercooled liquids

2008 ◽  
Vol 93 (11) ◽  
pp. 111913 ◽  
Author(s):  
Y. Q. Cheng ◽  
E. Ma ◽  
H. W. Sheng
Keyword(s):  
Supercooled Liquids ◽  
Glass Forming Ability ◽  
Glass Forming ◽  
Structure Dynamics

scholarly journals Anticrystal Engineering of Ketoprofen and Ester Local Anesthetics: Ionic Liquids or Deep Eutectic Mixtures?

Pharmaceutics ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 368 ◽  
Author(s):  
Anita Umerska ◽  
Klaudia Bialek ◽  
Julija Zotova ◽  
Marcin Skotnicki ◽  
Lidia Tajber
Keyword(s):  
Ionic Liquids ◽  
Supercooled Liquids ◽  
Glass Forming Ability ◽  
Molar Ratios ◽  
Glass Forming ◽  
Eutectic Mixtures ◽  
Carboxylate Anions ◽  
Quench Cooling ◽  
Crystallization Tendency ◽  
Low Solubility

Ionic liquids (ILs) and deep eutectic mixtures (DEMs) are potential solutions to the problems of low solubility, polymorphism, and low bioavailability of drugs. The aim of this work was to develop and investigate ketoprofen (KET)-based ILs/DEMs containing an ester local anesthetic (LA): benzocaine (BEN), procaine (PRO) and tetracaine (TET) as the second component. ILs/DEMs were prepared via a mechanosynthetic process that involved the mixing of KET with an LA in a range of molar ratios and applying a thermal treatment. After heating above the melting point and quench cooling, the formation of supercooled liquids with Tgs that were dependent on the composition was observed for all KET-LA mixtures with exception of that containing 95 mol% of BEN. The KET-LA mixtures containing either ≥ 60 mol% BEN or 95 mol% of TET showed crystallization to BEN and TET, respectively, during either cooling or second heating. KET decreased the crystallization tendency of BEN and TET and increased their glass-forming ability. The KET-PRO systems showed good glass-forming ability and did not crystallize either during the cooling or during the second heating cycle irrespective of the composition. Infrared spectroscopy and molecular modeling indicated that KET and LAs formed DEMs, but in the KET-PRO systems small quantities of carboxylate anions were present.

Induction period of the crystallization of silver nitrate solutions in ethylene glycol

1991 ◽  
Vol 56 (10) ◽  
pp. 2142-2147
Author(s):  
Ivo Sláma
Keyword(s):  
Ethylene Glycol ◽  
Silver Nitrate ◽  
Induction Period ◽  
Glass Forming Ability ◽  
Transformation Theory ◽  
Concentration Region ◽  
Glass Forming ◽  
Temperature Transformation ◽  
Silver Nitrate Solutions ◽  
Nitrate Solutions

The dependence of the induction period of crystallization on supercooling was examined for the silver nitrate-ethylene glycol system over the concentration region of silver nitrate lome fraction of 0 to 0.12. Addition of AgNO3 to ethylene glycol was found to increase considerably the critical induction period of crystallization, although to a lesser extent than Ca(NO3)2, CaCl2, ZnCl2, LiCl and LiNO3 do. The effect of these salts on the critical induction period of crystallization in dimethylsulfoxide, dimethylformamide, dimethylacetamide and methanol was compared in terms of the solvent-rich composition limit of the glass-forming ability. By using the TTT(Time-Temperature-Transformation) theory, it has been deduced that the effect of the salts on the critical induction period of crystallization of ethylene glycol is probably due to the different dependences of viscosity on their concentration in ethylene glyco in the supercooling region.

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