THE INFLUENCE OF PEAK SHOCK STRESS ON THE QUASI-STATIC RELOAD RESPONSE OF HCP METALS

2008 ◽  
Author(s):  
E. K. Cerreta ◽  
G. T. Gray ◽  
C. P. Trujillo ◽  
D. W. Brown ◽  
C. N. Tomé ◽  
...  
Keyword(s):  
Peak Shock ◽  
Shock Stress

The impact of peak shock stress on the microstructure and shear behavior of 1018 steel

2007 ◽  
Vol 55 (18) ◽  
pp. 6356-6364 ◽  
Author(s):  
Lisa M. Dougherty ◽  
Ellen K. Cerreta ◽  
Erik A. Pfeif ◽  
Carl P. Trujillo ◽  
George T. Gray
Keyword(s):  
Shear Behavior ◽  
Peak Shock ◽  
The Impact ◽  
Shock Stress

scholarly journals The influence of peak shock stress on the high pressure phase transformation in Zr

2014 ◽  
Vol 500 (3) ◽  
pp. 032003 ◽  
Author(s):  
E K Cerreta ◽  
F L Addessio ◽  
C A Bronkhorst ◽  
D W Brown ◽  
J P Escobedo ◽  
...  
Keyword(s):  
High Pressure ◽  
Phase Transformation ◽  
High Pressure Phase ◽  
Peak Shock ◽  
Pressure Phase ◽  
Shock Stress

scholarly journals Откол в сапфире при ударном сжатии в различных кристаллографических направлениях

2020 ◽  
Vol 90 (6) ◽  
pp. 961
Author(s):  
И.А. Черепанов ◽  
А.С. Савиных ◽  
С.В. Разоренов
Keyword(s):  
Shock Wave ◽  
Shock Compression ◽  
Spall Strength ◽  
Wave Profiles ◽  
Peak Shock ◽  
Shock Stress ◽  
Crystallographic Orientations

Shock wave profiles of sapphire with eight crystallographic orientations с m, a, s, r, g, n and d -cut were measured at shock stresses in the range 15–20 GPa. Measured values of spall strength depend on direction of shock compression and peak shock stress. The largest spall strength values ~12–13 GPa were recorded for peak shock stress 16 GPa along the a-axis and the m-direction.

scholarly journals The influence of peak shock stress on the high pressure phase transformation in zirconium

2012 ◽  
Vol 26 ◽  
pp. 02013 ◽  
Author(s):  
E.K. Cerreta ◽  
J.P. Escobedo ◽  
P.A. Rigg ◽  
F.L. Addessio ◽  
T. Lookman ◽  
...  
Keyword(s):  
High Pressure ◽  
Phase Transformation ◽  
High Pressure Phase ◽  
Peak Shock ◽  
Pressure Phase ◽  
Shock Stress

scholarly journals Stress-induced differential gene expression in cardiac tissue

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ana Elisa T. S. de Carvalho ◽  
Marco A. Cordeiro ◽  
Luana S. Rodrigues ◽  
Daniela Ortolani ◽  
Regina C. Spadari
Keyword(s):  
Gene Expression ◽  
Stress Response ◽  
Left Ventricle ◽  
Differential Gene Expression ◽  
Cardiac Tissue ◽  
Stressful Situation ◽  
Adaptive Mechanism ◽  
Number Of Genes ◽  
Differential Gene ◽  
Shock Stress

AbstractThe stress response is adaptive and aims to guarantee survival. However, the persistence of a stressor can culminate in pathology. Catecholamines released as part of the stress response over activate beta adrenoceptors (β-AR) in the heart. Whether and how stress affects the expression of components of the intracellular environment in the heart is still, however, unknown. This paper used microarray to analyze the gene expression in the left ventricle wall of rats submitted to foot shock stress, treated or not treated with the selective β2-AR antagonist ICI118,551 (ICI), compared to those of non-stressed rats also treated or not with ICI, respectively. The main findings were that stress induces changes in gene expression in the heart and that β2-AR plays a role in this process. The vast majority of genes disregulated by stress were exclusive for only one of the comparisons, indicating that, in the same stressful situation, the profile of gene expression in the heart is substantially different when the β2-AR is active or when it is blocked. Stress induced alterations in the expression of such a large number of genes seems to be part of stress-induced adaptive mechanism.

The CRZ-1 Transcription Factor Regulates Hsp 80 Involves in the Acquisition of Thermotolerance, and NCA-2 for Calcium Stress Tolerance in Neurospora Crassa

2021 ◽  
Author(s):  
Avishek Roy ◽  
Ranjan Tamuli
Keyword(s):  
Transcription Factor ◽  
Heat Shock ◽  
Neurospora Crassa ◽  
Stress Condition ◽  
Stress Conditions ◽  
Start Codon ◽  
Expression Levels ◽  
Heat Shock Stress ◽  
Shock Proteins ◽  
Shock Stress

Abstract Heat shock proteins (Hsps) are molecular chaperones and required for survival of organisms under heat stress conditions. In this study, we studied Hsp80, a member of the Hsp90 family, in Neurospora crassa. The expression of hsp80 was severely reduced in the N. crassa calcineurin B subunit RIP-mutant (cnb-1RIP) strains under the heat shock conditions. Furthermore, the expression levels of cnb-1, hsp60, hsp80, and the calcineurin-regulated transcription factor crz-1 were increased, but expression levels were reduced in the presence of the calcineurin inhibitor FK506 under the heat shock stress in the N. crassa wild type. Therefore, the calcineurin-crz-1 signaling pathway transcriptionally regulates hsp60 and hsp80 under the heat shock stress condition in N. crassa. In addition, the transcript levels of trm-9 and nca-2, a Ca2+ sensor and a Ca2+ ATPase, respectively, were increased under the heat shock stress condition. Moreover, the expression of the hsp80, but not the hsp60, was reduced in the Δtrm-9, Δnca-2, and the Δtrm-9 Δnca-2 double mutants. These results suggested that hsp80, trm-9, and nca-2 play a role in coping the heat shock stress in N. crassa. We found that CRZ-1 binds to 5ʹ-CCTTCACA-3ʹ and 5ʹ-AGCGGAGC-3ʹ 8 bp nucleotide sequences, located about 1075 bp and 679 bp upstream of the ATG start codon, respectively, of hsp80. We also found that CRZ-1 binds to an 8 bp nucleotide sequence 5ʹ-ACCGCGCC-3ʹ, located 234 bp upstream of the ATG start codon of nca-2 under Ca2+ stress condition. Thus, cnb-1, hsp60, hsp80, and crz-1 are involved in the heat shock stress response in N. crassa. Moreover, CRZ-1 upregulates the expressions of hsp80 and nca-2 under the heat shock stress and Ca2+ stress conditions, respectively, in N. crassa.

Identification of cis and trans components of a novel heat shock stress regulatory pathway in Saccharomyces cerevisiae

1993 ◽  
Vol 13 (1) ◽  
pp. 248-256
Author(s):  
N Kobayashi ◽  
K McEntee
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Stress Response ◽  
Heat Shock ◽  
Reporter Gene ◽  
Heat Shock Element ◽  
Cis Acting ◽  
Heat Shock Stress ◽  
Specific Complex ◽  
Cis And Trans ◽  
Shock Stress

The stress-responsive DDR2 gene (previously called DDRA2) of Saccharomyces cerevisiae is transcribed at elevated levels following stress caused by heat shock or DNA damage. Previously, we identified a 51-bp promoter fragment, oligo31/32, which conferred heat shock inducibility on the heterologous CYC1-lacZ reporter gene in S. cerevisiae (N. Kobayashi and K. McEntee, Proc. Natl. Acad. Sci. USA 87:6550-6554, 1990). Using a series of synthetic oligonucleotides, we have identified a pentanucleotide, CCCCT (C4T), as an essential component of this stress response sequence. This element is not a binding site for the well-characterized heat shock transcription factor which recognizes a distinct cis-acting heat shock element in the promoters of many heat shock genes. Here we demonstrate the ability of oligonucleotides containing the C4T sequence to confer heat shock inducibility on the reporter gene and show that the presence of two such elements produces more than additive effects on induction. Gel retardation experiments have been used to demonstrate specific complex formation between C4T-containing fragments and one or more yeast proteins. Formation of these complexes was not competed by fragments containing mutations in the C4T sequence nor by heat shock element-containing competitor DNAs. Fragments containing the C4T element bound to a single 140-kDa polypeptide, distinct from heat shock transcription factors in yeast crude extracts. These experiments identify key cis- and trans-acting components of a novel heat shock stress response pathway in S. cerevisiae.

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