Characterization of long-range surface-plasmon-polariton waveguides

2005 ◽  
Vol 98 (4) ◽  
pp. 043109 ◽  
Author(s):  
P. Berini ◽  
R. Charbonneau ◽  
N. Lahoud ◽  
G. Mattiussi
2015 ◽  
Vol 23 (13) ◽  
pp. 17421 ◽  
Author(s):  
Norman R. Fong ◽  
Pierre Berini ◽  
R. Niall Tait

2009 ◽  
Vol 95 (9) ◽  
pp. 091104 ◽  
Author(s):  
Fang Liu ◽  
Ruiyuan Wan ◽  
Yunxiang Li ◽  
Yidong Huang ◽  
Yoshikatsu Miura ◽  
...  

2016 ◽  
Vol 28 (6) ◽  
pp. 633-636 ◽  
Author(s):  
Lanting Ji ◽  
Tong Liu ◽  
Guobing He ◽  
Xiaoqiang Sun ◽  
Xibin Wang ◽  
...  

Sensors ◽  
2019 ◽  
Vol 19 (3) ◽  
pp. 631 ◽  
Author(s):  
Oleksiy Krupin ◽  
Pierre Berini

Straight long-range surface plasmon-polariton (LRSPP) waveguides as biosensors for label-free detection are discussed. The sensors consist of 5-μm-wide 35-nm-thick gold stripes embedded in a low-index optical-grade fluoropolymer (CYTOPTM) with fluidic channels etched to the Au surface of the stripes. This work demonstrates the application of the LRSPP biosensors for the detection of human cardiac troponin I (cTnI) protein. cTnI is a biological marker for acute myocardial infarction (AMI), often referred to as a heart attack, which can be diagnosed by elevated levels of cTnI in patient blood. Direct and sandwich assays were developed and demonstrated over the concentration range from 1 to 1000 ng/mL, yielding detection limits of 430 pg/mL for the direct assay and 28 pg/mL for the sandwich assay (1 standard deviation), the latter being physiologically relevant to the early detection or onset of AMI. In addition, a novel approach for data analysis is proposed, where the analyte response is normalized to the response of the antibody layer.


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