scholarly journals Gas Phase Counting of Low Energy Beta‐Emitters

1950 ◽  
Vol 21 (2) ◽  
pp. 158-162 ◽  
Author(s):  
W. Bernstein ◽  
R. Ballentine
Keyword(s):  
Gas Phase ◽  
Low Energy ◽  
Beta Emitters

scholarly journals Low-energy positron scattering from gas-phase uracil

2014 ◽  
Vol 68 (7) ◽  
Author(s):  
Jan Franz ◽  
Franco A. Gianturco ◽  
Isabella Baccarelli
Keyword(s):  
Gas Phase ◽  
Low Energy ◽  
Positron Scattering

Postcolumn Radionuclide Detection of Low-Energy .beta. Emitters in Capillary Electrophoresis

1994 ◽  
Vol 66 (14) ◽  
pp. 2382-2389 ◽  
Author(s):  
Scott. Tracht ◽  
Verna. Toma ◽  
Jonathan V. Sweedler
Keyword(s):  
Capillary Electrophoresis ◽  
Low Energy ◽  
Radionuclide Detection ◽  
Beta Emitters

scholarly journals The effect of adenine protonation on RNA phosphodiester backbone bond cleavage elucidated by deaza-nucleobase modifications and mass spectrometry

2019 ◽  
Vol 47 (14) ◽  
pp. 7223-7234 ◽  
Author(s):  
Elisabeth Fuchs ◽  
Christoph Falschlunger ◽  
Ronald Micura ◽  
Kathrin Breuker
Keyword(s):  
Mass Spectrometry ◽  
Gas Phase ◽  
Vibrational Excitation ◽  
Bond Cleavage ◽  
Low Energy ◽  
Biological Processes ◽  
Phosphodiester Backbone ◽  
Collisionally Activated Dissociation ◽  
Rna Backbone ◽  
Ionic Hydrogen Bonds

Abstract The catalytic strategies of small self-cleaving ribozymes often involve interactions between nucleobases and the ribonucleic acid (RNA) backbone. Here we show that multiply protonated, gaseous RNA has an intrinsic preference for the formation of ionic hydrogen bonds between adenine protonated at N3 and the phosphodiester backbone moiety on its 5′-side that facilitates preferential phosphodiester backbone bond cleavage upon vibrational excitation by low-energy collisionally activated dissociation. Removal of the basic N3 site by deaza-modification of adenine was found to abrogate preferential phosphodiester backbone bond cleavage. No such effects were observed for N1 or N7 of adenine. Importantly, we found that the pH of the solution used for generation of the multiply protonated, gaseous RNA ions by electrospray ionization affects phosphodiester backbone bond cleavage next to adenine, which implies that the protonation patterns in solution are at least in part preserved during and after transfer into the gas phase. Our study suggests that interactions between protonated adenine and phosphodiester moieties of RNA may play a more important mechanistic role in biological processes than considered until now.

scholarly journals Investigation of activation energies for dissociation of host-guest complexes in the gas phase using low-energy collision induced dissociation

2019 ◽  
Vol 54 (5) ◽  
pp. 437-448 ◽  
Author(s):  
Parisa Bayat ◽  
David Gatineau ◽  
Denis Lesage ◽  
Sina Marhabaie ◽  
Alexandre Martinez ◽  
...  
Keyword(s):  
Gas Phase ◽  
Activation Energies ◽  
Low Energy ◽  
Collision Induced Dissociation ◽  
Energy Collision
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