Magnetic Rotation Spectra of Nitric Oxide in the Near Infrared

1960 ◽  
Vol 33 (4) ◽  
pp. 1117-1123 ◽  
Author(s):  
Glen A. Mann ◽  
C. D. Hause
Keyword(s):  
Nitric Oxide ◽  
Near Infrared ◽  
Magnetic Rotation

Nitric oxide release activated near-Infrared photothermal agent for synergistic tumor treatment

Biomaterials ◽  
2021 ◽  
pp. 121017
Author(s):  
Yunjian Xu ◽  
Shiqi Wang ◽  
Zhenjiang Chen ◽  
Rui Hu ◽  
Yihua Zhao ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Near Infrared ◽  
Tumor Treatment ◽  
Nitric Oxide Release

scholarly journals Spatiotemporal Intracellular Nitric Oxide Signaling Captured Using Internalized, Near-Infrared Fluorescent Carbon Nanotube Nanosensors

Nano Letters ◽  
2014 ◽  
Vol 14 (8) ◽  
pp. 4887-4894 ◽  
Author(s):  
Zachary W. Ulissi ◽  
Fatih Sen ◽  
Xun Gong ◽  
Selda Sen ◽  
Nicole Iverson ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Carbon Nanotube ◽  
Near Infrared ◽  
Nitric Oxide Signaling ◽  
Fluorescent Carbon

scholarly journals Near-Infrared Photoactivatable Nitric Oxide Donors with Integrated Photoacoustic Monitoring

2018 ◽  
Vol 140 (37) ◽  
pp. 11686-11697 ◽  
Author(s):  
Effie Y. Zhou ◽  
Hailey J. Knox ◽  
Christopher J. Reinhardt ◽  
Gina Partipilo ◽  
Mark J. Nilges ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Near Infrared ◽  
Nitric Oxide Donors

Near-infrared light-mediated and nitric oxide-supplied nanospheres for enhanced synergistic thermo-chemotherapy

2019 ◽  
Vol 7 (4) ◽  
pp. 548-555 ◽  
Author(s):  
Chuan Zhang ◽  
Qiqing Li ◽  
Yue Zhao ◽  
Hou Liu ◽  
Shanliang Song ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light

Near infrared light/glutathione-responsive nanospheres for expanding nitric oxide application and enhancing synergistic thermal-chemotherapy.

scholarly journals Near-Infrared Light-Responsive Nitric Oxide Delivery Platform for Enhanced Radioimmunotherapy

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Xuanfang Zhou ◽  
Zhouqi Meng ◽  
Jialin She ◽  
Yaojia Zhang ◽  
Xuan Yi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Delivery System ◽  
Near Infrared ◽  
Combined Therapy ◽  
Tumor Model ◽  
Immune Checkpoint Blockade ◽  
Infrared Light ◽  
High Dose ◽  
High Concentration ◽  
Therapy Strategy

AbstractRadiotherapy (RT) is a widely used way for cancer treatment. However, the efficiency of RT may come with various challenges such as low specificity, limitation by resistance, high dose and so on. Nitric oxide (NO) is known a very effective radiosensitizer of hypoxic tumor. However, NO cannot circulate in body with high concentration. Herein, an NIR light-responsive NO delivery system is developed for controlled and precisely release of NO to hypoxic tumors during radiotherapy. Tert-Butyl nitrite, which is an efficient NO source, is coupled to Ag2S quantum dots (QDs). NO could be generated and released from the Ag2S QDs effectively under the NIR irradiation due to the thermal effect. In addition, Ag is also a type of heavy metal that can benefit the RT therapy. We demonstrate that Ag2S NO delivery platforms remarkably maximize radiotherapy effects to inhibit tumor growth in CT26 tumor model. Furthermore, immunosuppressive tumor microenvironment is improved by our NO delivery system, significantly enhancing the anti-PD-L1 immune checkpoint blockade therapy. 100% survival rate is achieved by the radio-immune combined therapy strategy based on the Ag2S NO delivery platforms. Our results suggest the promise of Ag2S NO delivery platforms for multifunctional cancer radioimmunotherapy.

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