A technique for real-time visualization of flow structure in high-speed flows

2002 ◽  
Vol 14 (10) ◽  
pp. 3449-3452 ◽  
Author(s):  
Brian Thurow ◽  
James Hileman ◽  
Walter Lempert ◽  
Mo Samimy
Keyword(s):  
Real Time ◽  
Flow Structure ◽  
High Speed ◽  
Real Time Visualization ◽  
High Speed Flows

Real-time visualization of network attacks on high-speed links

IEEE Network ◽  
2004 ◽  
Vol 18 (5) ◽  
pp. 30-39 ◽  
Author(s):  
Hyogon Kim ◽  
Inhye Kang ◽  
Saewoong Bahk
Keyword(s):  
Real Time ◽  
High Speed ◽  
Network Attacks ◽  
Real Time Visualization

scholarly journals Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Martina Rangl ◽  
Atsushi Miyagi ◽  
Julia Kowal ◽  
Henning Stahlberg ◽  
Crina M. Nimigean ◽  
...  
Keyword(s):  
Real Time ◽  
Conformational Changes ◽  
Cyclic Nucleotide ◽  
High Speed ◽  
Function Analysis ◽  
Stable Conformation ◽  
Mesorhizobium Loti ◽  
Force Microscopy ◽  
Atomic Force ◽  
Real Time Visualization

AbstractEukaryotic cyclic nucleotide-modulated (CNM) ion channels perform various physiological roles by opening in response to cyclic nucleotides binding to a specialized cyclic nucleotide-binding domain. Despite progress in structure-function analysis, the conformational rearrangements underlying the gating of these channels are still unknown. Here, we image ligand-induced conformational changes in single CNM channels from Mesorhizobium loti (MloK1) in real-time, using high-speed atomic force microscopy. In the presence of cAMP, most channels are in a stable conformation, but a few molecules dynamically switch back and forth (blink) between at least two conformations with different heights. Upon cAMP depletion, more channels start blinking, with blinking heights increasing over time, suggestive of slow, progressive loss of ligands from the tetramer. We propose that during gating, MloK1 transitions from a set of mobile conformations in the absence to a stable conformation in the presence of ligand and that these conformations are central for gating the pore.

Real-time colour Denisyuk setup for analyzing high-speed flows

2006 ◽  
Author(s):  
Jean Michel Desse ◽  
Jean-Louis Tribillon
Keyword(s):  
Real Time ◽  
High Speed ◽  
High Speed Flows
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