Effect of Saturation on Cyclic Volumetric Change of Compacted Silty Sands

Author(s):  
E. Yee ◽  
P. M. Duku ◽  
J. P. Stewart
Keyword(s):  
2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii342-iii342
Author(s):  
Naoki Kagawa ◽  
Ryuichi Hirayama ◽  
Chisato Yokota ◽  
Yasuyoshi Chiba ◽  
Yasunori Fujimoto ◽  
...  

Abstract BACKGROUND Spontaneous regression in intracranial germ cell tumors has been reported in some literatures, but the mechanism has not been well known. We retrospectively measured the tumor volume before chemoradiotherapy and analyzed factors that influence reduction of tumor volume. PATIENTS AND METHODS Plural MRI scans were done before the first course of chemotherapy regimen in 27 patients with primary intracranial germinomas. Their age ranged from 8 to 31 years. 35 lesions from them were enrolled and included 13 pineal, 4 neurohypophyseal, 4 basal ganglia, 4 bifocal type, and 2 multiple lesions. All regions were verified as pure germinoma or HCG-producing germinoma by histopathological examination. Tumor volume of 35 lesions was analyzed by volumetric assessment based on MRI. Ratio of volumetric change between the first MRI and the scan immediately before chemotherapy was defined as shrinking rate (%). Period between disease onset and the first chemotherapy was 20 to 47 days. Diagnostic radiation dose was calculated in each case. RESULTS Initial tumor volume ranged from 0.962 to 72.356 cubic centimeters (mean: 8.27). Diagnostic radiation dose: 40.5 to 910.1 mGy. Shrinking rate ranged from -57.8 to 85.4% (mean: 30.8). In 10 regions, shrinking rate was within 30%. Shrinking rate was significant positively influenced by diagnostic radiation dose (p<0.05) and negatively influenced by initial volume (p<0.05). But, other factors such as age, sex, histopathological parameters did not influence tumor shrinkage. CONCLUSION This study shows that the volume of intracranial germ cell tumors is changing dynamically before chemoradiotherapy in many cases. Diagnostic exposure to low-dose radiation influences tumor shrinkage of intracranial germinomas.


2022 ◽  
Vol 16 (1) ◽  
pp. 1-15
Author(s):  
Philipp Bernhard ◽  
Simon Zwieback ◽  
Nora Bergner ◽  
Irena Hajnsek

Abstract. Arctic ice-rich permafrost is becoming increasingly vulnerable to terrain-altering thermokarst, and among the most rapid and dramatic of these changes are retrogressive thaw slumps (RTSs). They initiate when ice-rich soils are exposed and thaw, leading to the formation of a steep headwall which retreats during the summer months. The impacts and the distribution and scaling laws governing RTS changes within and between regions are unknown. Using TanDEM-X-derived digital elevation models, we estimated RTS volume and area changes over a 5-year time period from winter 2011/12 to winter 2016/17 and used for the first time probability density functions to describe their distributions. We found that over this time period all 1853 RTSs mobilized a combined volume of 17×106 m3 yr−1, corresponding to a volumetric change density of 77 m3 yr−1 km−2. Our remote sensing data reveal inter-regional differences in mobilized volumes, scaling laws, and terrain controls. The distributions of RTS area and volumetric change rates follow an inverse gamma function with a distinct peak and an exponential decrease for the largest RTSs. We found that the distributions in the high Arctic are shifted towards larger values than at other study sites We observed that the area-to-volume scaling was well described by a power law with an exponent of 1.15 across all study sites; however the individual sites had scaling exponents ranging from 1.05 to 1.37, indicating that regional characteristics need to be taken into account when estimating RTS volumetric changes from area changes. Among the terrain controls on RTS distributions that we examined, which included slope, adjacency to waterbodies, and aspect, the latter showed the greatest but regionally variable association with RTS occurrence. Accounting for the observed regional differences in volumetric change distributions, scaling relations, and terrain controls may enhance the modelling and monitoring of Arctic carbon, nutrient, and sediment cycles.


2006 ◽  
Vol 14 (7S_Part_2) ◽  
pp. P129-P129
Author(s):  
Leon M. Aksman ◽  
Nicholas Firth ◽  
Marzia Antonella Scelsi ◽  
Jonathan M. Schott ◽  
Sebastien Ourselin ◽  
...  

2020 ◽  
Vol 45 (11) ◽  
pp. 2540-2555 ◽  
Author(s):  
Rafael C. Carvalho ◽  
David M. Kennedy ◽  
Yakufu Niyazi ◽  
Chloe Leach ◽  
Teresa M. Konlechner ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document