Cardiovascular Effects of Continuous Positive Airway Pressure in Patients with Heart Failure and Obstructive Sleep Apnea

2003 ◽  
Vol 348 (13) ◽  
pp. 1233-1241 ◽  
Author(s):  
Yasuyuki Kaneko ◽  
John S. Floras ◽  
Kengo Usui ◽  
Julie Plante ◽  
Ruzena Tkacova ◽  
...  
Keyword(s):  
Heart Failure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Cardiovascular Effects ◽  
Obstructive Sleep ◽  
Patients With Heart Failure

Prognosis of Patients With Heart Failure and Obstructive Sleep Apnea Treated With Continuous Positive Airway Pressure

CHEST Journal ◽  
2008 ◽  
Vol 133 (3) ◽  
pp. 690-696 ◽  
Author(s):  
Takatoshi Kasai ◽  
Koji Narui ◽  
Tomotaka Dohi ◽  
Naotake Yanagisawa ◽  
Sugao Ishiwata ◽  
...  
Keyword(s):  
Heart Failure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Obstructive Sleep ◽  
Patients With Heart Failure

scholarly journals Obstructive sleep apnea and cardiovascular effects-a review

2009 ◽  
Vol 4 (2) ◽  
pp. 41-45
Author(s):  
AKM Mosharraf Hossain ◽  
Mostofa Midhat Pasha
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Cardiovascular Effects ◽  
Intrathoracic Pressure ◽  
Fold Increase ◽  
Timely Initiation ◽  
Obstructive Sleep

Obstructive sleep apnea (OSA) is the most common form of sleep-disordered breathing, affecting 5-15% of the population. It is characterized by intermittent episodes of partial or complete obstruction of the upper airway during sleep that disrupts normal ventilation and sleep architecture, and is typically associated with excessive daytime sleepiness, snoring, and witnessed apneas. Patients with obstructive sleep apnea present risk to the general public safety by causing 8-fold increase in vehicle accidents, and they may themselves also suffer from the physiologic consequences of OSA; these include hypertension, coronary artery disease, stroke, congestive heart failure, pulmonary hypertension, and cardiac arrhythmias. Of these possible cardiovascular consequences, the association between OSA and hypertension has been found to be the most convincing. Although the exact mechanism has not been understood, there is some evidence that OSA is associated with frequent apneas causing mechanical effects on intrathoracic pressure, cardiac function, and intermittent hypoxemia, which may in turn cause endothelial dysfunction and increase in sympathetic drive. Therapy with continuous positive airway pressure has been demonstrated to improve cardiopulmonary hemodynamics in patients with OSA and may reverse the endothelial cell dysfunction. Limited availability of diagnostic measures and unawareness of physicians, many patients with OSA remain undiagnosed. Awareness and timely initiation of an effective treatment may prevent potential deleterious cardiovascular effects of OSA. Key words: Obstructive Sleep apnea, Hypertension, Atherosclerosis, Continuous positive airway pressure.   doi:10.3329/uhj.v4i2.2075 University Heart Journal Vol. 4 No. 2 July 2008 p.41-45

scholarly journals Obstructive Sleep Apnea in Heart Failure: Review of Prevalence, Treatment with Continuous Positive Airway Pressure, and Prognosis

2018 ◽  
Vol 45 (3) ◽  
pp. 151-161 ◽  
Author(s):  
Himad K. Khattak ◽  
Faisal Hayat ◽  
Salpy V. Pamboukian ◽  
Harvey S. Hahn ◽  
Brian P. Schwartz ◽  
...  
Keyword(s):  
Heart Failure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Preserved Ejection Fraction ◽  
Obstructive Sleep ◽  
Artery Disease ◽  
The Relationship

Obstructive sleep apnea is a sleep-related breathing disorder that has a major impact on cardiovascular function. It has been associated with hypertension, coronary artery disease, cardiac arrhythmias, sudden cardiac death, and heart failure. This review focuses on the relationship between obstructive sleep apnea and heart failure with either reduced or preserved ejection fraction. We discuss the pathophysiology of obstructive sleep apnea, as well as its prevalence, treatment outcomes with continuous positive airway pressure, and prognosis in these 2 distinct types of heart failure. We also identify areas in which further work is needed to improve our understanding of this association in heart failure patients.

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