scholarly journals Imbalance in T-Helper 17 Cells and Targeted Therapy in an Infant with SAM-like Syndrome

2019 ◽  
Vol 381 (22) ◽  
pp. 2176-2178 ◽  
Author(s):  
Angela Hernández-Martín ◽  
Rebeca Kennedy-Batalla ◽  
Elvira Cañedo ◽  
Esther Bernaldo-de-Quirós ◽  
Begoña Carazo-Gallego ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
T Helper ◽  
T Helper 17 ◽  
T Helper 17 Cells

Assessment of the role of T Helper 17 cells in the pathogenesis of Acne Vulgaris

2019 ◽  
Vol 10 (12) ◽  
pp. 1435
Author(s):  
Nahla Maher ◽  
HebatAllah Ismail Gawdat ◽  
Heba Helmy El Hadidi ◽  
Olfat Gamil Shaker
Keyword(s):  
Acne Vulgaris ◽  
T Helper ◽  
T Helper 17 ◽  
T Helper 17 Cells

T helper 17 cells: discovery, function, and physiological trigger

2010 ◽  
Vol 67 (9) ◽  
pp. 1407-1421 ◽  
Author(s):  
Miriam Beer Torchinsky ◽  
J. Magarian Blander
Keyword(s):  
T Helper ◽  
T Helper 17 ◽  
T Helper 17 Cells

T-helper 17 cells: The driving force of psoriasis and psoriatic arthritis

2012 ◽  
Vol 15 (6) ◽  
pp. 531-537 ◽  
Author(s):  
In Seol Yoo ◽  
Jeung Hoon Lee ◽  
Seung Tak Song ◽  
Jin Hyun Kim ◽  
Hyun Ji Lee ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Driving Force ◽  
T Helper ◽  
T Helper 17 ◽  
T Helper 17 Cells

A case of refractory lupus nephritis complicated by psoriasis vulgaris that was controlled with secukinumab

Lupus ◽  
2018 ◽  
Vol 27 (7) ◽  
pp. 1202-1206 ◽  
Author(s):  
Y Satoh ◽  
K Nakano ◽  
H Yoshinari ◽  
S Nakayamada ◽  
S Iwata ◽  
...  
Keyword(s):  
Lupus Nephritis ◽  
Lupus Erythematosus ◽  
Psoriasis Vulgaris ◽  
Tissue Sample ◽  
Interleukin 17 ◽  
T Helper ◽  
T Helper 17 ◽  
T Helper 17 Cells ◽  
Biopsy Tissue ◽  
Interleukin 17A

It has been reported that T helper 17 cells are involved in the pathogenesis of systemic lupus erythematosus, but there is no report on interleukin-17-targeted therapy. We report a case of a 62-year-old female who presented with psoriasis vulgaris and refractory lupus nephritis. Because her conditions were resistant to conventional treatment, and flow cytometry confirmed the proliferation of activated T helper 17 cells in peripheral blood, and examination of a renal biopsy tissue sample confirmed infiltration of numerous interleukin-17-positive lymphocytes to the renal interstitium, administration of the anti-interleukin-17A antibody secukinumab was initiated. After starting secukinumab the clinical and biological features were improved.

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