High tumor cell dissociation (spray like pattern of invasion) is associated with poor prognosis in carcinoma of the cervix uteri

2005 ◽  
Vol 66 (S 1) ◽  
Author(s):  
LC Horn ◽  
U Fischer ◽  
J Einenkel ◽  
UD Braumann ◽  
K Bilek
Keyword(s):  
Tumor Cell ◽  
Poor Prognosis ◽  
Cervix Uteri ◽  
Cell Dissociation ◽  
Pattern Of Invasion ◽  
Tumor Cell Dissociation

scholarly journals Tumor Cell Dissociation Removes Malignant Bladder Tumors

Chem ◽  
2020 ◽  
Vol 6 (9) ◽  
pp. 2283-2299
Author(s):  
Qunqun Bao ◽  
Ping Hu ◽  
Weiwei Ren ◽  
Yuedong Guo ◽  
Jianlin Shi
Keyword(s):  
Tumor Cell ◽  
Bladder Tumors ◽  
Cell Dissociation ◽  
Tumor Cell Dissociation

scholarly journals ALL-1 gene at chromosome 11q23 is consistently altered in acute leukemia of early infancy

Blood ◽  
1993 ◽  
Vol 82 (2) ◽  
pp. 544-546 ◽  
Author(s):  
G Cimino ◽  
F Lo Coco ◽  
A Biondi ◽  
L Elia ◽  
A Luciano ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Tumor Cell ◽  
Chromosome Aberrations ◽  
Poor Prognosis ◽  
Genetic Locus ◽  
Genetic Defect ◽  
Early Infancy ◽  
Acute Leukemias ◽  
Chromosome 11Q23 ◽  
Characteristic Features

Abstract Early infancy (< 1 year of age), massive tumor cell burden, and extremely poor prognosis are characteristic features of a particular subset of childhood acute leukemias (AL). In these cases, chromosome aberrations at the 11q23 band are the most frequently reported cytogenetic abnormalities. We have recently cloned a genetic locus named ALL-1, in which DNA breakpoints are clustered in leukemic patients with 11q23 aberrations. Analysis of the ALL-1 genomic configuration in DNA from 15 infants with AL showed specific ALL-1 rearrangements in 12 cases (80%), including 5 with normal karyotypes. These findings indicate that a consistent genetic defect underlies this particular leukemic subset.

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