scholarly journals Effects of EGb 761® Ginkgo biloba Extract on Mitochondrial Function and Oxidative Stress

2003 ◽  
Vol 36 ◽  
pp. 15-23 ◽  
Keyword(s):  
Oxidative Stress ◽  
Mitochondrial Function ◽  
Ginkgo Biloba ◽  
Ginkgo Biloba Extract ◽  
Egb 761 ◽  
And Oxidative Stress

Stabilization of mitochondrial function by Ginkgo biloba extract (EGb 761)

2007 ◽  
Vol 56 (6) ◽  
pp. 493-502 ◽  
Author(s):  
Reham Abdel-Kader ◽  
Susanne Hauptmann ◽  
Uta Keil ◽  
Isabel Scherping ◽  
Kristina Leuner ◽  
...  
Keyword(s):  
Mitochondrial Function ◽  
Ginkgo Biloba ◽  
Ginkgo Biloba Extract ◽  
Egb 761

The Effect of Ginkgo biloba extract (EGb 761) on parameters of oxidative stress in different regions of aging rat brains after acute hypoxia

2011 ◽  
Vol 23 (4) ◽  
pp. 255-263 ◽  
Author(s):  
Rosemarie Martin ◽  
Christian Mozet ◽  
Hans Martin ◽  
Klaus Welt ◽  
Christoph Engel ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ginkgo Biloba ◽  
Acute Hypoxia ◽  
Ginkgo Biloba Extract ◽  
Egb 761 ◽  
Aging Rat

Impact of Ginkgo Biloba Extract EGb 761 on Ischemia/Reperfusion – Induced Oxidative Stress Products Formation in Rat Forebrain

2006 ◽  
Vol 26 (7-8) ◽  
pp. 1341-1351 ◽  
Author(s):  
A. Uríková ◽  
E. Babušíková ◽  
D. Dobrota ◽  
A. Drgová ◽  
P. Kaplán ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ginkgo Biloba ◽  
Ischemia Reperfusion ◽  
Ginkgo Biloba Extract ◽  
Egb 761 ◽  
Rat Forebrain

scholarly journals Ginkgo biloba extract (EGb 761) mitigates methotrexate-induced testicular insult in rats: Targeting oxidative stress, energy deficit and spermatogenesis

2021 ◽  
Vol 143 ◽  
pp. 112201
Author(s):  
Dina F. Mansour ◽  
Dalia O. Saleh ◽  
Omar A. Ahmed-Farid ◽  
Mona Rady ◽  
Rofanda M. Bakeer ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ginkgo Biloba ◽  
Ginkgo Biloba Extract ◽  
Energy Deficit ◽  
Egb 761 ◽  
Stress Energy

scholarly journals Effects of Physical Activity and Ginkgo Biloba on Cognitive Function and Oxidative Stress Modulation in Ischemic Rats

2016 ◽  
Vol 26 (03) ◽  
pp. 158-164 ◽  
Author(s):  
Hassan Bafandeh Gharamaleki ◽  
Ladan Vaghef
Keyword(s):  
Oxidative Stress ◽  
Cerebral Ischemia ◽  
Ginkgo Biloba ◽  
Ginkgo Biloba Extract ◽  
Treadmill Running ◽  
Protective Effects ◽  
Oxidative Stress Biomarkers ◽  
Neuroprotective Effects ◽  
Memory Impairments ◽  
And Oxidative Stress

AbstractEither exercise or Ginkgo biloba is reported to improve cognitive functioning. The aim of this study is to compare the protective effects of forced exercise and Ginkgo biloba on oxidative stress as well as memory impairments induced by transient cerebral ischemia. Adult male Wistar rats were treated with treadmill running or Ginkgo biloba extract for 2 weeks before cerebral ischemia. Memory was assessed using a Morris water maze (MWM) task. At the end of the behavioral testing, oxidative stress biomarkers were evaluated in the hippocampus tissue. As expected, the cerebral ischemia induced memory impairment in the MWM task, and oxidative stress in the hippocampus. These effects were significantly prevented by treadmill running. Indeed, it ameliorated oxidative stress and memory deficits induced by ischemia. In contrast, Ginkgo biloba was not as effective as exercise in preventing ischemia-induced memory impairments. The results confirmed the neuroprotective effects of treadmill running on hippocampus-dependent memory.

scholarly journals Effects of Ginkgo biloba extract on brain oxidative condition after cisplatin exposure

2016 ◽  
Vol 39 (6) ◽  
pp. 100 ◽  
Author(s):  
Duygu Aydin ◽  
Emine G G Peker ◽  
Meryem D Karakurt ◽  
Ayşe Gurel ◽  
Mustafa Ayyildiz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Nitric Oxide ◽  
Ginkgo Biloba ◽  
Antioxidant Properties ◽  
Ginkgo Biloba Extract ◽  
Egb 761 ◽  
Pathogenetic Mechanism ◽  
Tissue Samples ◽  
Oxidative Condition ◽  
Brain Tissues

Purpose: The purpose of this study was to evaluate the efficacy of Ginkgo biloba extract (EGb 761) on oxidative events of brain in cisplatin-administrated rats. Methods: Rats were divided into four experimental groups: 1) control (n=6); 2) cisplatin (8 mg/kg, intraperitoneally one dose, n=6); 3) EGb 761 (100 mg/kg intraperitoneally for 15 days, n=6); and 4) cisplatin + EGb 761 (n=6). After drug administration, rats were sacrificed and brain tissues were removed. Nitric oxide (NO), malondialdehyde (MDA) and glutathione (GSH) levels were evaluated in brain tissues. Results: Single dose cisplatin administration significantly increased NO and GSH levels, but decreased MDA levels in brain tissue samples. EGb 761 treatment reversed the effects of cisplatin on NO and GSH levels, but did not affect the decreased MDA levels. Conclusion: Results of the study indicate that oxidative stress can be an important pathogenetic mechanism of cisplatin-induced neurotoxicity. EGb 761, an standardized extract of G. biloba leaves that has antioxidant properties, may improve the oxidative stress-related neurological side effects of cisplatin.

A Ginkgo Biloba Extract (EGb 761) Prevents Mitochondrial Aging by Protecting Against Oxidative Stress

1998 ◽  
Vol 24 (2) ◽  
pp. 298-304 ◽  
Author(s):  
Juan Sastre ◽  
Arantxa Millan ◽  
Jose Garcia de la Asuncion ◽  
Rosa Pla ◽  
Gloria Juan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ginkgo Biloba ◽  
Ginkgo Biloba Extract ◽  
Egb 761
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