Expression of Angiotensin II Receptors Type 1 and Type 2 in Human Preadipose Cells During Differentiation

2002 ◽  
Vol 34 (11/12) ◽  
pp. 709-715 ◽  
Author(s):  
P. Schling
Keyword(s):  
Angiotensin Ii ◽  
Angiotensin Ii Receptors

SHEEP HYPOTHALAMUS CONTAINS A NON-ANGIOTENSIN LIGAND FOR TYPE 1 AND TYPE 2 ANGIOTENSIN II RECEPTORS

1993 ◽  
Vol 20 (9) ◽  
pp. 555-562 ◽  
Author(s):  
Julie Blasioli ◽  
Athena Kladis ◽  
Iain J. Clarke ◽  
Duncan J. Campbell
Keyword(s):  
Angiotensin Ii ◽  
Angiotensin Ii Receptors

scholarly journals Thyroid Hormone Increases TGF-β1 in Cardiomyocytes Cultures Independently of Angiotensin II Type 1 and Type 2 Receptors

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Gabriela Placoná Diniz ◽  
Marcela Sorelli Carneiro-Ramos ◽  
Maria Luiza Morais Barreto-Chaves
Keyword(s):  
Angiotensin Ii ◽  
Cardiac Hypertrophy ◽  
Transforming Growth Factor ◽  
Cardiac Fibroblasts ◽  
Angiotensin Ii Receptors ◽  
Cardiomyocyte Hypertrophy ◽  
Tgf Β1

TH-induced cardiac hypertrophyin vivois accompanied by increased cardiac Transforming Growth Factor-β1 (TGF-β1) levels, which is mediated by Angiotensin II type 1 receptors (AT1R) and type 2 receptors (AT2R). However, the possible involvement of this factor in TH-induced cardiac hypertrophy is unknown. In this study we evaluated whether TH is able to modulate TGF-β1 in isolated cardiac, as well as the possible contribution of AT1R and AT2R in this response. The cardiac fibroblasts treated withT3did not show alteration on TGF-β1 expression. However, cardiomyocytes treated withT3presented an increase in TGF-β1 expression, as well as an increase in protein synthesis. The AT1R blockade prevented theT3-induced cardiomyocyte hypertrophy, while the AT2R blockage attenuated this response. TheT3-induced increase on TGF-β1 expression in cardiomyocytes was not changed by the use of AT1R and AT2R blockers. These results indicate that Angiotensin II receptors are not implicated inT3-induced increase on TGF-βexpression and suggest that the trophic effects exerted byT3on cardiomyocytes are not dependent on the higher TGF-β1 levels, since the AT1R and AT2R blockers were able to attenuate theT3-induced cardiomyocyte hypertrophy but were not able to attenuate the increase on TGF-β1 levels promoted byT3.

Type-1 and type-2 angiotensin II receptors in fetal rat brain

1991 ◽  
Vol 198 (1) ◽  
pp. 89-92 ◽  
Author(s):  
Tsutsumi Keisuke ◽  
Mohan Viswanathan ◽  
Christer Strömberg ◽  
Juan M. Saavedra
Keyword(s):  
Angiotensin Ii ◽  
Rat Brain ◽  
Angiotensin Ii Receptors ◽  
Fetal Rat ◽  
Fetal Rat Brain

Blockade of central angiotensin II type 1 and type 2 receptors suppresses adrenalectomy-induced NaCl intake in rats

1996 ◽  
Vol 66 (1-2) ◽  
pp. 47-50 ◽  
Author(s):  
O. Galaverna ◽  
C. Polidori ◽  
R.R. Sakai ◽  
F. Liénard ◽  
S.Y. Chow ◽  
...  
Keyword(s):  
Angiotensin Ii

Angiotensin II-induced thirst, but not sodium appetite, via AT1 receptors in organum cavum prelamina terminalis

1995 ◽  
Vol 268 (6) ◽  
pp. R1401-R1405 ◽  
Author(s):  
M. el Ghissassi ◽  
S. N. Thornton ◽  
S. Nicolaidis
Keyword(s):  
Angiotensin Ii ◽  
Salt Intake ◽  
High Sensitivity ◽  
Ang Ii ◽  
Nacl Solution ◽  
At1 Receptors ◽  
Sodium Appetite ◽  
Specific Antagonist

The angiotensin receptor specificity, with respect to fluid intake, of the organum cavum prelamina terminalis (OCPLT), a recently discovered discrete forebrain structure with high sensitivity to angiotensin II (ANG II), was investigated. ANG II (10 ng) microinjected into the OCPLT significantly increased water consumption but did not induce intake of a hypertonic (3%) NaCl solution. Losartan, an ANG II type 1 (AT1) receptor-specific antagonist, produced dose-related (1-100 ng) inhibition of ANG II-induced drinking. The ANG II type 2 receptor-specific antagonist CGP-42112A was ineffective. Intake of the 3% NaCl solution in response to microinjection of either of the antagonists into the OCPLT was never observed. These findings suggest that water intake produced by microinjection of ANG II into the OCPLT is mediated by AT1 receptors uniquely and that, in contrast to other regions of the brain, these receptors do not induce salt intake when stimulated by ANG II.

Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis and antagonizes angiotensin II type 1 receptor action: An in vitro gene transfer study

Life Sciences ◽  
1998 ◽  
Vol 63 (19) ◽  
pp. PL289-PL295 ◽  
Author(s):  
Takehiko Yamada ◽  
Masahiro Akishita ◽  
Matthew J. Pollman ◽  
Gary H. Gibbons ◽  
Victor J. Dzau ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Angiotensin Ii ◽  
Gene Transfer ◽  
Cell Apoptosis ◽  
Receptor Action ◽  
Muscle Cell Apoptosis ◽  
Transfer Study
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