One-Step Stereocontrolled Synthesis of α-Anomeric Carboxylic Acid Esters from Unprotected Glycosyl Donors: A Water-Soluble Aspirin Pro-Drug Analogue­

Synthesis ◽  
2002 ◽  
Vol 2002 (14 Special Issue) ◽  
Author(s):  
Stephen Hanessian ◽  
Vincent Mascitti ◽  
Pu-Ping Lu ◽  
Hideki Ishida
Keyword(s):  
Carboxylic Acid ◽  
Water Soluble ◽  
Stereocontrolled Synthesis ◽  
One Step ◽  
Acid Esters ◽  
Glycosyl Donors

Aminimides. II. A one-step synthesis of aminimides from carboxylic acid esters

1967 ◽  
Vol 45 (21) ◽  
pp. 2619-2623 ◽  
Author(s):  
William J. McKillip ◽  
Robert C. Slagel
Keyword(s):  
Carboxylic Acid ◽  
Reaction Temperature ◽  
Sodium Methoxide ◽  
General Applicability ◽  
Acyl Substituent ◽  
One Step ◽  
The One ◽  
Substituent Influence ◽  
Acid Esters

The general applicability of preparing aminimides from esters and insitu generated 1,1,1-trimethylaminimine is reported. Acyclic, alicyclic, aromatic, and heteroaromatic trimethylaminimides have been synthesized by the one-step reaction. The synthetic scheme consists of reacting an ester with a 1,1,1-trimethylhydrazinium salt in the presence of an anhydrous base such as sodium methoxide. The choice of solvent, reaction temperature, and base and the electronegativity of the acyl substituent influence the ease of aminimide formation.

A One-Step Synthesis of 2,4-Unsubstituted Quinoline-3-carboxylic Acid Esters fromo-Nitrobenzaldehydes

2010 ◽  
Vol 75 (10) ◽  
pp. 3488-3491 ◽  
Author(s):  
Hariharan Venkatesan ◽  
Frances M. Hocutt ◽  
Todd K. Jones ◽  
Michael H. Rabinowitz
Keyword(s):  
Carboxylic Acid ◽  
One Step ◽  
Acid Esters

ChemInform Abstract: A One-Step Synthesis of 2,4-Unsubstituted Quinoline-3-carboxylic Acid Esters from o-Nitrobenzaldehydes.

ChemInform ◽  
2010 ◽  
Vol 41 (40) ◽  
pp. no-no
Author(s):  
Hariharan Venkatesan ◽  
Frances M. Hocutt ◽  
Todd K. Jones ◽  
Michael H. Rabinowitz
Keyword(s):  
Carboxylic Acid ◽  
One Step ◽  
Acid Esters

Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters

2019 ◽  
Author(s):  
Jiang Wang ◽  
Brian P. Cary ◽  
Peyton Beyer ◽  
Samuel H. Gellman ◽  
Daniel Weix
Keyword(s):  
Carboxylic Acid ◽  
Solid Support ◽  
Reaction Conditions ◽  
Decarboxylative Coupling ◽  
New Strategy ◽  
The Cross ◽  
Acyl Donors ◽  
Acid Esters

A new strategy for the synthesis of ketones is presented based upon the decarboxylative coupling of N-hydroxyphthalimide (NHP) esters with S-2-pyridyl thioesters. The reactions are selective for the cross-coupled product because NHP esters act as radical donors and the thioesters act as acyl donors. The reaction conditions are general and mild, with over 40 examples presented, including larger fragments and the 20-mer peptide Exendin(9-39) on solid support.

One-step, ultrasonication-mobilized, solvent-free extraction/synthesis of nanocurcumin from turmeric

RSC Advances ◽  
2015 ◽  
Vol 5 (60) ◽  
pp. 48391-48398 ◽  
Author(s):  
Judy Gopal ◽  
Manikandan Muthu ◽  
Se-Chul Chun
Keyword(s):  
Solvent Free ◽  
Water Soluble ◽  
One Step

One step ultrasonication for direct recovery of water soluble nanocurcumin from turmeric.

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