Base-mediated Reaction of Quaternary Ammonium Salts with Nitroarenes - Their Useful Functionalization via Vicarious Nucleophilic Substitution (VNS)

Synthesis ◽  
2002 ◽  
Vol 2002 (05) ◽  
pp. 674-680 ◽  
Author(s):  
Andrzej Jończyk ◽  
Anna Kowalkowska
Author(s):  
Tomasz K. Olszewski ◽  
Anna Brol

An effective protocol for quaternization of simple 1-aminoalkylphosphonic acids under basic conditions and using Me2SO4 as convenient alkylating agent is reported. In the course of reaction phosphonic acid quaternary ammonium...


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