A Radical Carbon-carbon Bond Forming Reaction: Indium Mediated Radical Addition to β-Substituted Conjugated Alkenes in Aqueous Media

Synlett ◽  
2002 ◽  
Vol 2002 (04) ◽  
pp. 0631-0633 ◽  
Author(s):  
Doo Ok Jang ◽  
Dae Hyan Cho
Keyword(s):  
Aqueous Media ◽  
Radical Addition ◽  
Carbon Bond ◽  
Bond Forming ◽  
Carbon Carbon Bond

Photocatalytic Cascade Carbon-Carbon Bond-Forming Radical Reaction in Aqueous Media

Synlett ◽  
2013 ◽  
Vol 24 (12) ◽  
pp. 1578-1582 ◽  
Author(s):  
Shigeru Kohtani ◽  
Hideto Miyabe ◽  
Eito Yoshioka ◽  
Eri Tanaka
Keyword(s):  
Aqueous Media ◽  
Radical Reaction ◽  
Carbon Bond ◽  
Bond Forming ◽  
Carbon Carbon Bond

scholarly journals Tandem Carbon—Carbon Bond-Forming Radical Addition-Cyclization Reaction of Oxime Ether and Hydrazone.

ChemInform ◽  
2003 ◽  
Vol 34 (48) ◽  
Author(s):  
Hideto Miyabe ◽  
Masafumi Ueda ◽  
Kayoko Fujii ◽  
Azusa Nishimura ◽  
Takeaki Naito
Keyword(s):  
Radical Addition ◽  
Cyclization Reaction ◽  
Oxime Ether ◽  
Carbon Bond ◽  
Bond Forming ◽  
Carbon Carbon Bond

Tandem Carbon−Carbon Bond-Forming Radical Addition-Cyclization Reaction of Oxime Ether and Hydrazone

2003 ◽  
Vol 68 (14) ◽  
pp. 5618-5626 ◽  
Author(s):  
Hideto Miyabe ◽  
Masafumi Ueda ◽  
Kayoko Fujii ◽  
Azusa Nishimura ◽  
Takeaki Naito
Keyword(s):  
Radical Addition ◽  
Cyclization Reaction ◽  
Oxime Ether ◽  
Carbon Bond ◽  
Bond Forming ◽  
Carbon Carbon Bond

scholarly journals Application of Polyamines and Amino Acid Derivatives Based on 2-Azabicycloalkane Backbone in Enantioselective Aldol Reaction

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5166
Author(s):  
Dominika Iwan ◽  
Karolina Kamińska ◽  
Elżbieta Wojaczyńska
Keyword(s):  
Catalytic Activity ◽  
Amino Acid ◽  
Aldol Reaction ◽  
Aqueous Media ◽  
Amino Acid Derivatives ◽  
Carbon Bond ◽  
Bond Forming ◽  
Backbone Amide ◽  
Carbon Carbon Bond ◽  
Excellent Chemical

Carbon–carbon bond forming reactions, such as aldol reaction and condensation, belong to extremely desired transformations as manifested by >25,000 entries in SciFinder. Their stereoselective variant requires the use of an appropriate catalyst with a strictly defined structure. Hence, chiral 2-azabicycloalkane-based catalysts were designed, synthesized and tested in a stereoselective aldol reaction between cyclic/acyclic ketone and p-nitrobenzaldehyde both in organic and aqueous media. Among catalysts containing a chiral bicyclic backbone, amide based on 2-azabicyclo[3.2.1]octane and pyrrolidine units showed the best catalytic activity and afforded aldol product in excellent chemical yields (up to 95%) and good diastereo- and enantioselectivity (dr 22:78, ee up to 63%).

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