Entrapment of Lipases in Hydrophobic Sol-Gel-Materials: Efficient Heterogeneous Biocatalysts in Aqueous Medium

Synthesis ◽  
2000 ◽  
Vol 2000 (06) ◽  
pp. 781-783 ◽  
Author(s):  
Manfred T. Reetz ◽  
Regina Wenkel ◽  
David Avnir
Keyword(s):  
Aqueous Medium ◽  
Sol Gel ◽  
Heterogeneous Biocatalysts

Second Generation Sol-Gel Encapsulated Lipases: Robust Heterogeneous Biocatalysts

2003 ◽  
Vol 345 (67) ◽  
pp. 717-728 ◽  
Author(s):  
Manfred T. Reetz ◽  
Patrick Tielmann ◽  
Wolfgang Wiesenhöfer ◽  
Werner Könen ◽  
Albin Zonta
Keyword(s):  
Second Generation ◽  
Sol Gel ◽  
Heterogeneous Biocatalysts

Study of the degradation of hybrid sol–gel coatings in aqueous medium

2014 ◽  
Vol 77 (11) ◽  
pp. 1799-1806 ◽  
Author(s):  
M.J. Juan-Díaz ◽  
M. Martínez-Ibáñez ◽  
M. Hernández-Escolano ◽  
L. Cabedo ◽  
R. Izquierdo ◽  
...  
Keyword(s):  
Aqueous Medium ◽  
Sol Gel

Synthesis of organosilicon sol-gel matrices and preparation of heterogeneous biocatalysts based on them

2014 ◽  
Vol 87 (6) ◽  
pp. 761-766 ◽  
Author(s):  
O. A. Kamanina ◽  
D. G. Fedoseeva ◽  
T. V. Rogova ◽  
O. N. Ponamoreva ◽  
I. V. Blokhin ◽  
...  
Keyword(s):  
Sol Gel ◽  
Heterogeneous Biocatalysts

scholarly journals Effects of precursor on the morphology and size of ZrO2 nanoparticles, synthesized by sol-gel method in non-aqueous medium

2012 ◽  
Vol 15 (6) ◽  
pp. 986-989 ◽  
Author(s):  
Mohammed Rafiq Hussain Siddiqui ◽  
Abdulaziz Ibrahim Al-Wassil ◽  
Abdullah Mohmmed Al-Otaibi ◽  
Refaat Mohamad Mahfouz
Keyword(s):  
Aqueous Medium ◽  
Sol Gel ◽  
Zro2 Nanoparticles ◽  
Gel Method ◽  
Sol Gel Method

scholarly journals Enantioselective Transamination in Continuous Flow Mode with Transaminase Immobilized in a Macrocellular Silica Monolith

2017 ◽  
Author(s):  
Ludivine van den Biggelaar ◽  
Patrice Soumillion ◽  
Damien P. Debecker
Keyword(s):  
Continuous Flow ◽  
Preferential Flow ◽  
Kinetic Resolution ◽  
Flow Reactor ◽  
Sol Gel ◽  
Flow Mode ◽  
Chiral Amine ◽  
Silica Monoliths ◽  
Covalent Grafting ◽  
Heterogeneous Biocatalysts

ω-Transaminases have been immobilized on macrocellular silica monoliths and used as heterogeneous biocatalysts in a continuous flow mode enantioselective transamination reaction. The support was prepared by a sol-gel method based on emulsion-templating. The enzyme was immobilized on the structured silica monoliths both by adsorption, and by covalent grafting using amino-functionalized silica monoliths and glutaraldehyde as a coupling agent. A simple reactor set-up based on the use of a heat-shrinkable Teflon tube is presented and successfully used for the continuous flow kinetic resolution of a chiral amine, 4-bromo-α-methylbenzylamine. The porous structure of the supports ensures effective mass transfer and the reactor works in the plug flow regime without preferential flow paths. When immobilized in the monolith and used in the flow reactor, transaminases retain their activity and their enantioselectivity. The solid biocatalyst is also shown to be stable both on stream and during storage. These essential features pave the way to the successful development of an environmentally friendly process for chiral amines production.

Preparation of SiO2/Nb2O5/ZnO mixed oxide by sol–gel method and its application for adsorption studies and on-line preconcentration of cobalt ions from aqueous medium

2014 ◽  
Vol 239 ◽  
pp. 233-241 ◽  
Author(s):  
Kristiany Moreira Diniz ◽  
Felipe Augusto Gorla ◽  
Emerson Schwingel Ribeiro ◽  
Marcela Betta Olimpio do Nascimento ◽  
Rodrigo José Corrêa ◽  
...  
Keyword(s):  
Aqueous Medium ◽  
Mixed Oxide ◽  
Sol Gel ◽  
Cobalt Ions ◽  
Gel Method ◽  
Sol Gel Method ◽  
Adsorption Studies ◽  
On Line

scholarly journals Enantioselective Transamination in Continuous Flow Mode with Transaminase Immobilized in a Macrocellular Silica Monolith

2017 ◽  
Author(s):  
Ludivine van den Biggelaar ◽  
Patrice Soumillion ◽  
Damien P. Debecker
Keyword(s):  
Continuous Flow ◽  
Preferential Flow ◽  
Kinetic Resolution ◽  
Flow Reactor ◽  
Sol Gel ◽  
Flow Mode ◽  
Chiral Amine ◽  
Silica Monoliths ◽  
Covalent Grafting ◽  
Heterogeneous Biocatalysts

ω-Transaminases have been immobilized on macrocellular silica monoliths and used as heterogeneous biocatalysts in a continuous flow mode enantioselective transamination reaction. The support was prepared by a sol-gel method based on emulsion templating. The enzyme was immobilized on the structured silica monoliths both by adsorption, and by covalent grafting using amino-functionalized silica monoliths and glutaraldehyde as a coupling agent. A simple reactor set-up based on the use of a heat-shrinkable Teflon tube is presented and successfully used for the continuous flow kinetic resolution of a chiral amine, 4-bromo-α-methylbenzylamine. The porous structure of the supports ensures effective mass transfer and the reactor works in the plug flow regime without preferential flow paths. When immobilized in the monolith and used in the flow reactor, transaminases retain their activity and their enantioselectivity. The solid biocatalyst is also shown to be stable both on stream and during storage. These essential features pave the way to the successful development of an environmentally friendly process for chiral amines production.

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