The number of biopsy specimens can influence the non-lifting sign in colorectal laterally spreading tumors

2021 ◽  
Vol 59 (04) ◽  
pp. 321-325
Author(s):  
Yang Liu ◽  
Ning Wei ◽  
Rui Hua Shi

Abstract Background Although the problem of whether to perform a biopsy before endoscopic treatment for colorectal laterally spreading tumor (LST) troubles clinicians, about 50 % of lesions still undergo a preceding biopsy. We aimed to explore factors affecting the non-lifting sign in LST and examine the influence of “biopsy-related factors”, such as the number of biopsy specimens and the interval after biopsy on non-lifting sign in cases with a history of biopsy. Methods Clinical data of 159 LSTs regarding age, gender, history of biopsy, tumor location, tumor size, the depth of submucosal invasion, tumor configuration, histologic type, location with respect to the fold, and result of non-lifting sign testing were investigated retrospectively. For patients with a history of biopsy, the period after biopsy and the number of biopsy specimens also were analyzed. Results Among 159 cases of LST, 112 were positive and 47 were negative for lifting signs. Biopsy history (p = 0.008), tumor size (p = 0.010), and location with respect to the fold (p = 0.022) were identified as factors affecting the non-lifting sign in multivariate analyses. In 75 LST cases with a history of biopsy, only the number of biopsies (p = 0.003) was identified as a factor affecting the non-lifting sign in multivariate analyses. Conclusions For LST, lesions with larger size, being across the fold, and biopsy history were predictive factors for non-lifting signs. Reducing the number of biopsies would reduce the occurrence of non-lifting signs when biopsy is necessary. The impact of the interval after the biopsy on the non-lifting sign will require further study.

2004 ◽  
Vol 37 (2) ◽  
pp. 225-244 ◽  
Author(s):  
Kathleen Canning

Thereis perhaps no more fitting way to honor Vernon Lidtke than to demonstrate, in the form of this essay, that the questions he posed to his students years ago continue to provide a grid for contemplating and analyzing historical subjects, both familiar and new. One such question involved the impact of one concept's transformation upon another: would class persist as a crucial historical category once it had confronted the differences of gender? This question preoccupied me in previous work and I return to it here, taking stock of that which has changed since I first contemplated this question, in the fields of both German and European gender history. Another question that remains an object of debate is the longer-term trajectory of the history of women and gender: how might we define the point at which its work of subversion or revision is complete? What directions might this field take once “mainstream” histories have successfully incorporated its findings? This essay aims to compare the ways in which the keywords class, citizenship, and welfare state have been redefined, expanded, or circumscribed through the turn to culture, language, and gender. This comparative exercise allows me to expand Vernon's original questions to include citizenship, the critical concept in my more recent scholarship, and to review the potentials and promises of main-streaming across the so-called Atlantic divide.


2021 ◽  
Author(s):  
Dilek Erdem ◽  
Irem Karaman

Aim: This study aimed to assess the impact of coronavirus disease 2019 (COVID-19) phobia and related factors on attitude towards COVID-19 vaccine in cancer patients. Methods: A prospective cross-sectional descriptive study was conducted with 300 adult patients using a validated COVID-19 Phobia Scale (C19P-S) and related survey to determine the factors affecting vaccine acceptance between May–June 2021. Results: Regarding the COVID-19 vaccine willingness, 86.7% accepted vaccination, 6.3% were hesitant and 7% refused vaccination. Patients that accepted vaccination had significantly higher C19P-S scores in general, and in psychological and psychosomatic subdivisions. Univariate analysis revealed that increased age, being retired, and being married were significantly associated with willingness to be vaccinated against COVID-19. Conclusion: The majority of patients had high coronophobia levels which were associated with increased willingness for the COVID-19 vaccines. Minimizing negative attitudes towards vaccines will most likely be achieved by raising awareness in the cancer population about COVID-19 vaccine.


Author(s):  
Jay J. Ye ◽  
Michael R. Tan ◽  
Chung H. Shum

Context.— Studies on the adoption of voice recognition in health care have mostly focused on turnaround time and error rate, with less attention paid to the impact on the efficiency of the providers. Objective.— To study the impact of voice recognition on the efficiency of grossing biopsy specimens. Design.— Timestamps corresponding to barcode scanning for biopsy specimen bottles and cassettes were retrieved from the pathology information system database. The time elapsed between scanning a specimen bottle and the corresponding first cassette was the length of time spent on the gross processing of that specimen and is designated as the specimen time. For the first specimen of a case, the specimen time additionally included the time spent on dictating the clinical information. Therefore, the specimen times were divided into the following 2 categories: first-specimen time and subsequent-specimen time. The impact of voice recognition on specimen times was studied using both univariate and multivariate analyses. Results.— Specimen complexity, prosector variability, length of clinical information text, and the number of biopsies the prosector grossed that day were the major determinants of specimen times. Adopting voice recognition had a negligible impact on specimen times. Conclusions.— Adopting voice recognition in the gross room removes the need to hire transcriptionists without negatively impacting the efficiency of the prosectors, resulting in an overall cost saving. Using computer scripting to automatically enter clinical information (received through the electronic order interface) into report templates may potentially increase the grossing efficiency in the future.


1992 ◽  
Vol 33 (3) ◽  
pp. 441-465 ◽  
Author(s):  
Linzi Manicom

Although South African women's history has been growing in volume and sophistication over the past decade, the impact of gender analysis has yet to be felt in mainstream or radical historiography. One reason for this neglect is the way in which the categories of both ‘gender’ and ‘women’ have been conceived – with ‘women’ assumed to have a stable referent and ‘gender’ treated as synonymous with women. Those areas of social life where women are not immediately present have thus remained unreconstructed by the theoretical implications of gender. This is particularly the case with the history of ‘the state’.The article identifies and looks critically at the major paradigms of South African women's and gender history in terms of how the relationship between ‘the state’ and ‘women’ is implicitly or explicitly represented. It argues that the understanding of the category ‘women’ as socially and historically constructed (as evident in more recently published gender history) provides a way of moving beyond the more static or abstractly posed state-versus-women relationship. This requires too that ‘the South African state’ be understood not as unitary or coherent but as institutionally diverse with different objectives being taken up and produced as policy and practice. The project then becomes one of understanding South African state formation as a gendered and gendering process, of exploring the different institutional sites and ruling discourses in which gender identities and categories are constructed.


2020 ◽  
Author(s):  
Ravi Philip Rajkumar

Objectives: The impact of the COVID-19 pandemic has varied widely across nations and even in different regions of the same nation. Some of this variability may be due to the interplay of pre-existing demographic, psychological, social and health-related factors in a given population. Methods: Data on the COVID-19 prevalence, crude mortality and case fatality rates were obtained from official government statistics for 24 regions of India. The relationship between these parameters and demographic, social, psychological and health-related indices in these states was examined using both bivariate and multivariate analyses. Results: A variety of factors - state population, sex ratio, and burden of diarrhoeal disease and ischemic heart disease - were associated with measures of the impact of COVID-19 on bivariate analyses. On multivariate analyses, prevalence and crude mortality rate were both significantly and negatively associated with the sex ratio. Conclusions: These results suggest that the transmission and impact of COVID-19 in a given population may be influenced by a number of variables, with demographic factors showing the most consistent association.


2020 ◽  
Vol 9 (03) ◽  
pp. 162-169
Author(s):  
Ehsan Alimohammadi ◽  
Seyed Reza Bagheri ◽  
Nasrin Delfani ◽  
Roya Safari-Faramani ◽  
Maryam Janatolmakan

Abstract Background Pediatric high-grade gliomas (PHGGs) consist of a heterogeneous class of central nervous system (CNS) neoplasms with a poor prognosis. We aimed to present our 10-year experience in the management of children with high-grade glioma focusing on patients’ survival and related factors. Methods All pediatric patients with high- grade glioma (HGG) who were admitted to our center between May 2009 and May 2018 were investigated. Overall survival (OS) was calculated from the time of diagnosis until the day of death. The impact of suggested variables on survival was evaluated using the univariate and multivariate analyses. Results There were 41 children with non–brain stem high-grade glioma (NBSHGG). The mean OS of patients was 21.24 ± 10.16 months. The extent of resection (p = 0.002, hazard ratio [HR] = 4.84), the grade of the tumor (p = 0.017, HR = 4.36), and temozolomide (TMZ) therapy (p = 0.038, HR = 3.57) were the independent predictors of OS in children with NBSHGG. Age, gender, tumor location, and size of tumor were not associated with the survival of these patients. Conclusion HGGs are uncommon pediatric tumors with an aggressive nature and a poor prognosis. Our results revealed that in NBSHGG cases, children with maximal safe tumor resection and children that received temozolomide therapy as well as children with grade III of the tumor had higher survival.


2011 ◽  
Vol 2 (2) ◽  
pp. 35-64 ◽  
Author(s):  
Sanjay K. Jain ◽  
Manika Jain

The paper aims at examining the impact of various consumer and product characteristics on adoption of e-commerce among consumers in India. The study is based on primary data collected through survey of consumers residing in and around Delhi. A structured non- disguised questionnaire has been employed for collecting the information from the respondents about their demographics, shopping orientations, security and privacy concerns, technological familiarity, past online shopping experiences and intentions to buy various types of products through internet in future. Past online shopping satisfaction, recreational shopping orientation, education and income emerge as significant factors affecting consumer past online purchases. In respect of future online shopping intentions, only three consumer-related factors viz., past online shopping satisfaction, past online shopping frequency and education, are found as significant predictors. Amongst product characteristics, product expensiveness is found to be negatively related to consumer future online purchase intentions. While consumers appear quite willing to buy services online that are high in their intangible value proposition, they appear somewhat ambivalent in their intentions to buy online the 'frequently purchased products'. Some of the consumer and product characteristics do influence consumer adoption of e-commerce. Study findings entail interesting implications for the marketers. They need to give adequate attention to consumer and product characteristics while designing their e-marketing strategies. As compared to goods, the surveyed respondents have expressed greater willingness to buy services online in future. Services thus appear to be more promising product category for sale through internet channel in future.


Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Shelly Ozark ◽  
Andrea D Boan ◽  
Tanya N Turan ◽  
Charles Ellis ◽  
David L Bachman ◽  
...  

Background: Stroke is a leading cause of adult disability and reduction in quality of life, but little is known about the social, demographic, clinical and functional elements that contribute to perceived quality of life after stroke. Objective: To determine the factors associated with patient perception of the effect that stroke has on quality of life. Methods: The STEP-South Carolina Project surveyed 162 stroke survivors one year after their event, assessing clinical and functional outcomes and patient perceptions of the magnitude of the impact of stroke on their quality of life (“no effect”, “some effect”, or “great effect”). Multivariate analyses were performed to determine the relationship between the patients’ perceived effect of stroke on quality of life and demographic features, functional abilities, stroke severity, and medical comorbidities. Results: Multivariate analyses showed no difference in age, race, gender or insurance status. As shown in the table, multivariate analyses (adjusted for NIHSS, age, race, gender, and insurance status) demonstrated that a history of prior stroke, use of therapy services, lower functional independence in ADLs, not driving, and history of diabetes were associated with a patient’s perception of a “greater effect” on quality of life. Conclusion: The perception of the impact of stroke on quality of life is influenced by both functional outcomes and clinical factors post-stroke. Further study is needed to find ways of mitigating these factors to improve patient perceived quality of life.


2017 ◽  
Vol 11 (1) ◽  
pp. 81
Author(s):  
Sabiha Odabasi Cimer

Over the past two decades, Turkey has initiated a reform movement to change her classroom assessment system to accommodate performance-based alternative assessment methods in schools. However, research investigating the impact of assessment reform on learning and teaching in schools report that performance assessment approaches have not been implemented effectively. This study investigated the teacher related factors behind the adoption decisions of teachers of these changes introduced. Data for the study were collected through interviews with 53 biology teachers in 24 schools. According to the findings, teachers’ lack of self-agency, superficial understanding of the ideas introduced, mistrust that the innovations will work in practice, skepticism about the need for a change and inadequate knowledge and abilities as a result of ineffective dissemination and professional guidance were the main factors affecting the success of the reform. Suggestions to overcome barriers to reform and implications of the findings in managing change are presented and discussed at the end of the paper.


2020 ◽  
Vol 32 (2) ◽  
pp. 104 ◽  
Author(s):  
M. Mikkola ◽  
J. F. Hasler ◽  
J. Taponen

Despite a long history of bovine superovulation research, significant commercial applications did not start until the early 1970s. For some 20 years thereafter, superovulation represented the primary tool for the production of cattle embryos. In the early 1990s, commercial invitro production (IVP) was initiated in cattle. Although ovum pick-up and IVP are now commercially practiced on a wide scale, superovulation and embryo recovery by flushing remain a widespread and very effective approach to the production of cattle embryos. This review covers both the history and the effects of multiple factors on superovulation in Bos taurus cattle. There are three general protocols for suitable pre-FSH programming of donors so that gonadotrophin-responsive follicles are available. Superovulation protocols vary widely based on the FSH source, the diluent used, the number and timing of FSH injections and the timing and utilisation of various prostaglandins, controlled internal progesterone releasing devices, gonadotrophin-releasing hormone, and other means of controlling follicular development and ovulation. The number of oocytes that can be stimulated to grow and ovulate within any given donor can be estimated by either ultrasound-guided sonography or by measuring concentrations of anti-Müllerian hormone in the blood. Animal-related factors that can influence the efficacy of superovulation include cattle breed, age, parity, genetics, lactational status and reproductive history. In addition, nutrition, stress, season, climate, weather and several semen factors are discussed.


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