Age- and gender-related growth hormone responses to intravenous clonidine in healthy adults

2001 ◽  
Vol 11 (2) ◽  
pp. 128-135 ◽  
Author(s):  
J. Kimber ◽  
M. Sivenandan ◽  
L. Watson ◽  
C.J. Mathias
Keyword(s):  
Growth Hormone ◽  
Healthy Adults ◽  
Age And Gender ◽  
Hormone Responses ◽  
And Gender

Enhanced growth hormone responses to pyridostigmine challenge in patients with panic disorder

1997 ◽  
Vol 170 (2) ◽  
pp. 159-161 ◽  
Author(s):  
J. M. Cooney ◽  
J. V. Lucey ◽  
T. G. Dinan
Keyword(s):  
Growth Hormone ◽  
Panic Disorder ◽  
Comparison Group ◽  
Acetylcholinesterase Inhibitor ◽  
Age And Gender ◽  
Hormone Responses ◽  
The Difference ◽  
And Gender ◽  
Matched Comparison

BackgroundPanic disorder is associated with neuroendocrinological abnormalities, some of which overlap with those seen in major depression. To date, there has been little assessment of the role of cholinergic mechanisms in this disorder.MethodSixteen patients with DSM–III–R panic disorder and an age and gender-matched comparison group were administered 120 mg of the acetylcholinesterase inhibitor pyridostigmine. Growth hormone (GH) responses over a three-hour period were monitored.ResultsMean ΔGH, the difference between basal and the maximum pyridostigmine levels, was significantly greater in patients with panic disorder than in the comparison group.ConclusionsThis may reflect increased cholinergic responsivity in panic disorder.

Age and gender differences of endothelial function in 4739 healthy adults: the HUNT3 Fitness Study

2012 ◽  
Vol 20 (4) ◽  
pp. 531-540 ◽  
Author(s):  
Eli-Anne Skaug ◽  
Stian Thoresen Aspenes ◽  
Line Oldervoll ◽  
Bjørn Mørkedal ◽  
Lars Vatten ◽  
...  
Keyword(s):  
Gender Differences ◽  
Endothelial Function ◽  
Healthy Adults ◽  
Age And Gender ◽  
Age And Gender Differences ◽  
And Gender

EFFECT OF AGE AND GENDER ON FASTING AND FOOD-STIMULATED LEVELS OF CALCITONIN, PARATHYROID, AND GASTRIN HORMONES IN HEALTHY ADULTS

2019 ◽  
Vol 25 (6) ◽  
pp. 526-533
Author(s):  
Munther S. Momani ◽  
Ayman A. Zayed ◽  
Hussam H. Alhawari ◽  
Enas Abu Salim ◽  
Ahmad M. Ghazali ◽  
...  
Keyword(s):  
Healthy Adults ◽  
Age And Gender ◽  
And Gender ◽  
Effect Of Age

Growth hormone binding protein and growth hormone availability in acromegalic patients treated with long-acting octreotide (Sandostatin-LAR)

1997 ◽  
Vol 136 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Sanne Fisker ◽  
Andreas Kaal ◽  
Marcella Montini ◽  
Alberto Pedroncelli ◽  
Giorgio Pagani ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Binding Protein ◽  
Hormone Binding ◽  
Age And Gender ◽  
Growth Hormone Binding Protein ◽  
Igf I ◽  
Octreotide Treatment ◽  
Hormone Binding Protein ◽  
And Gender ◽  
Long Acting

Abstract Objective: In the medical treatment of acromegaly different factors are influencial; among these the impact on growth hormone binding protein (GHBP) has not been clarified. Design: Twenty acromegalic patients and nineteen age- and gender-matched normal subjects participated in this study. The patients were treated for 21 months with depot long-acting microsphere-enclosed octreotide (Sandostatin-LAR). Previously, all the patients were treated s.c. with octreotide t.i.d. After a 2-week wash-out period (baseline) the patients received the first i.m. injection of the long-acting octreotide. The first two injections were administered at 60-day intervals; thereafter the injections were at 28-day intervals. Methods: The levels of GHBP, complexed GHBP, growth hormone (GH) and insulin-like growth factor-I (IGF-I) were determined in fasting serum samples. Results: In the 2-week wash-out period GHBP levels decreased from 1·13 ± 0·17 to 0·92 ± 0·15 nmol/l (P < 0·05). During the 21-months treatment, GHBP increased again to 1·10 ± 0·16 nmol/l. In the age- and gender-matched control group GHBP levels were significantly higher at all times (1·95 ± 0·21 nmol/l, P(all) < 0·02). Mean levels of 8-h GH decreased from 12·6 ± 2·58 μg/l at baseline to 1·97 ± 0·20 μg/l after 21 months of treatment (P < 0·05). Mean 8-h GH levels were unchanged during long-acting octreotide treatment compared with levels during s.c. treatment (1·97 ± 0·20 μg/l and 1·90 ± 0·20 μg/l respectively). In fasting blood samples GH-complexed GHBP ranged from 13·8 ± 2·4% (9 months) to 25·4 ± 4·5% (baseline) of total GHBP. Serum IGF-I increased from 367 ± 45 to 764 ± 80 μg/l (P < 0·05) during the 2-week wash-out period and decreased to 290 ± 35 μg/l (P < 0·05) after 21 months of treatment with long-acting octreotide. IGF-I levels after 21 months were significantly lower than during s.c. octreotide treatment (P < 0·05). Conclusion: Serum GHBP levels are similar during treatment with long-acting octreotide as compared with regular octreotide. Furthermore, significant changes in GHBP can occur within 2 weeks. Finally, in addition to the lowering effect on GH levels, the induced increase in GHBP levels may imply a further advantage in octreotide treatment of acromegaly, circulating GH bound to GHBP may less readily reach the tissues. European Journal of Endocrinology 136 61–66

scholarly journals Lymphocyte subsets: Reference ranges in an age- and gender-balanced population of Omani healthy adults

2013 ◽  
Vol 83A (8) ◽  
pp. 739-744 ◽  
Author(s):  
Adhra Al-Mawali ◽  
Avinash Daniel Pinto ◽  
Raiya Al Busaidi ◽  
Ibrahim Al-Zakwani
Keyword(s):  
Lymphocyte Subsets ◽  
Healthy Adults ◽  
Reference Ranges ◽  
Age And Gender ◽  
And Gender

Influence of Age and Gender of Healthy Adults on Scoring Patterns on the Community Balance and Mobility Scale

2005 ◽  
Vol 57 (4) ◽  
pp. 285-292 ◽  
Author(s):  
Rohini Rocque ◽  
Doreen Bartlett ◽  
Janet Brown ◽  
S. Jayne Garland
Keyword(s):  
Healthy Adults ◽  
Age And Gender ◽  
And Gender

scholarly journals The impact of age and gender on right ventricular diastolic function among healthy adults

2017 ◽  
Vol 70 (4) ◽  
pp. 387-395 ◽  
Author(s):  
Antonello D’Andrea ◽  
Olga Vriz ◽  
Andreina Carbone ◽  
Francesco Ferrara ◽  
Marco Di Maio ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Diastolic Function ◽  
Healthy Adults ◽  
Age And Gender ◽  
Ventricular Diastolic Function ◽  
And Gender ◽  
Right Ventricular Diastolic Function ◽  
The Impact

Factor VIII: C Relationships to Selected Lipids, Age, and Gender in Healthy Adults

1990 ◽  
Vol 300 (2) ◽  
pp. 83-87 ◽  
Author(s):  
Maurine J. Corsaut ◽  
Thomas J. Bierma ◽  
R. Marilyn Kasa
Keyword(s):  
Factor Viii ◽  
Healthy Adults ◽  
Age And Gender ◽  
And Gender
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