Intravenous milrinone is no better than standard therapy for people admitted with acute exacerbation of chronic heart failure

2002 ◽  
Vol 6 (4) ◽  
pp. 154-155
Author(s):  
Marcus G Hennersdorf
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Acute Exacerbation ◽  
Standard Therapy ◽  
Better Than

scholarly journals Fibrinogen Level Predicts Outcomes in Critically Ill Patients with Acute Exacerbation of Chronic Heart Failure

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Zhongyuan Meng ◽  
Yaxin Zhao ◽  
Yan He
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Acute Exacerbation ◽  
Critically Ill ◽  
Roc Curve ◽  
Critically Ill Patients ◽  
Medical Information ◽  
Fibrinogen Level ◽  
Cox Model ◽  
Hazard Ratio

Background. Heart failure (HF) is a common cardiovascular disease, which is related to systemic inflammation for decades. Fibrinogen (FIB) is a sign of thrombosis and inflammation, which is associated with the prognosis of many diseases. Nevertheless, the role of fibrinogen level in the prognosis of critically ill patients with acute exacerbation of chronic heart failure is unclear. Methods. The data are from the Medical Information Mart for Intensive Care III (MIMIC III) database, which is a freely accessible critical care database. The primary outcome in our study was 90-day mortality. The prognostic value of fibrinogen was analyzed with receiver operating characteristic (ROC) curve analysis, Kaplan-Meier curve, and Cox model. Results. A total of 554 patients were included. Patients were divided into two groups, low fibrinogen level (<284 mg/dl) and high fibrinogen level (≥284 mg/dl), through the cut-off value of the ROC curve. The area under the ROC curve of fibrinogen for predicting 90-day mortality was 0.65 (95% CI: 0.59–0.70). In the unadjusted Cox model, compared with the low fibrinogen level (<284 mg/dl), the 90-day mortality of the hazard ratio (HR) with 95% confidence intervals (CI) of the high fibrinogen level is 3.33 (95% CI 2.15-5.15). In different multivariable Cox models, compared with the low fibrinogen level (<284 mg/dl), the 90-day mortality of the hazard ratio of the high fibrinogen level is from 2.83 to 3.13. In subgroup analyses, significant interactions were observed only in age, chronic kidney disease (CKD), and APS III scores. Conclusion. Our data suggest that high fibrinogen levels (≥284 mg/dl) independently predict mortality in critically ill patients with acute exacerbation of chronic heart failure. Our findings need to be further validated by large prospective studies and longer follow-up time.

scholarly journals Development of a Nursing Protocol for Hospitalized Patients with Reduced Cognitive Function in the Process of Recovery from Acute Exacerbation of Chronic Heart Failure

Health ◽  
2018 ◽  
Vol 10 (07) ◽  
pp. 879-901
Author(s):  
Haruka Otsu ◽  
Tsukiko Narasaki ◽  
Ayumi Kamura ◽  
Kyoko Maeda ◽  
Tomoko Sumiwaka ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cognitive Function ◽  
Chronic Heart Failure ◽  
Acute Exacerbation ◽  
Hospitalized Patients

Acute heart failure

2018 ◽  
Author(s):  
Kazem Rahimi
Keyword(s):  
Heart Failure ◽  
Cardiac Output ◽  
Chronic Heart Failure ◽  
Acute Exacerbation ◽  
Acute Heart Failure ◽  
Clinical Features ◽  
Clinical Syndrome ◽  
The Body ◽  
Cardiac Structure ◽  
New Onset

Heart failure is a clinical syndrome characterized by an inadequate cardiac output for the needs of the body in the absence of low filling pressures, and reflects abnormal cardiac structure or function. Although various definitions for acute heart failure (AHF) exist, here AHF is defined as new-onset heart failure or an acute exacerbation of chronic heart failure, requiring urgent therapy. Patients with AHF typically have clinical features of organ hypoperfusion, with or without pulmonary and peripheral oedema.

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