scholarly journals A systematic review of the role of human papilloma virus (HPV) testing within a cervical screening programme: summary and conclusions

2000 ◽  
Vol 83 (5) ◽  
pp. 561-565 ◽  
Author(s):  
J Cuzick ◽  
P Sasieni ◽  
P Davies ◽  
J Adams ◽  
C Normand ◽  
...  
Keyword(s):  
Systematic Review ◽  
Human Papilloma Virus ◽  
Screening Programme ◽  
Cervical Screening ◽  
Hpv Testing ◽  
Papilloma Virus

Colposcopy

2021 ◽  
pp. 543-564
Author(s):  
Aggie Jokhan ◽  
Joyce Aburam ◽  
Emma Sinfield ◽  
Debra Holloway
Keyword(s):  
Primary Care ◽  
Human Papilloma Virus ◽  
Clinical Features ◽  
Cervical Screening ◽  
Subsequent Treatment ◽  
Papilloma Virus ◽  
Liquid Based Cytology ◽  
Virus Testing

This chapter begins with an overview of the NHS cervical screening programme, then describes ways of taking samples for liquid-based cytology. The colposcopy procedure is detailed, and indications for referral are listed. Subsequent treatment and follow-up are explained, and the role of the nurse in cervical screening in primary care is covered. The human papilloma virus, testing, and vaccines are included, along with the clinical features and management of cervical polyps, and cervical ectropion are explained.

scholarly journals Technological advances: Have they improved standards? Review of outcomes from the Welsh cervical screening programme

2020 ◽  
pp. 096914132091827
Author(s):  
Alejandra Castanon
Keyword(s):  
Human Papilloma Virus ◽  
New Technologies ◽  
Screening Programme ◽  
Performance Indicator ◽  
Cervical Screening ◽  
Performance Standards ◽  
Substantial Impact ◽  
Papilloma Virus ◽  
Technological Advances ◽  
Virus Testing

Objectives Introduction of new technologies into cervical screening programmes has allowed more efficient programmes with less resources. We present an overview of screening technologies introduced into the Cervical Screening Wales programme and their evolution over time. Methods Data from the programme’s statistical report were used to evaluate its performance over a 17-year period between 2001/02 and 2017/18. Results The introduction of liquid-based cytology has had a substantial impact on reducing inadequate sample rates and on increasing the positive predictive value of cytology. Inadequate rates have increased following the implementation of human papilloma virus testing as a triage test for cytology. Further knock-on effects on standard reporting ranges are expected following the introduction of human papilloma virus testing as the primary screening test. New performance standards have been introduced to better reflect the performance of the programme at a time when disease prevalence is expected to fall as women vaccinated against human papilloma virus reach screening age. Conclusions Improvements to this cervical cancer screening programme as illustrated through performance indicator ranges suggest a major role played by technology.

HPV-testing in cervical screening

2016 ◽  
pp. 100-102
Author(s):  
O. Rykova ◽  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Human Papilloma Virus ◽  
Key Words ◽  
Cervical Screening ◽  
Pap Test ◽  
Carcinogenic Risk ◽  
Hpv Testing ◽  
Papilloma Virus ◽  
Liquid Based Cytology

The article presents modern laboratory aspects of cervical screening, which include assessment of infection with human papillomavirus (HPV) high carcinogenic risk. Key words: cervical cancer, cervical screening, traditional cytology, liquid-based cytology, PAP-test, human papilloma virus.

scholarly journals The Role of High-Risk Human Papilloma Virus Testing in the Surveillance of Cervical Cancer After Treatment

2015 ◽  
Vol 139 (11) ◽  
pp. 1437-1440 ◽  
Author(s):  
Miao Crystal Yu ◽  
R. Marshall Austin ◽  
Jeff Lin ◽  
Tiffany Beck ◽  
Sushil Beriwal ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Logistic Regression ◽  
High Risk ◽  
Human Papilloma Virus ◽  
Disease Recurrence ◽  
The United States ◽  
Hpv Testing ◽  
Bulky Disease ◽  
Papilloma Virus

Context Cervical cancer affects 12 000 women in the United States annually. However, despite its prevalence, there remains no good methodology to detect its recurrence. Objective To identify the role of cervicovaginal high-risk human papilloma virus (hr-HPV) testing in predicting cervical cancer recurrence. Design This is a retrospective study of patients who underwent hr-HPV testing as part of their routine surveillance for cervical cancer. Standard statistical analyses, including χ2 test and multivariable logistic regression, were performed with IBM SPSS 19.0. Results A total of 133 patients were identified, of whom 107 (80%) had squamous cell carcinoma. Ninety patients (68%) had bulky disease and were treated primarily with chemoradiation and brachytherapy. Of patients whose disease recurred, 5 patients (42%) had tested positive for hr-HPV during their surveillance period, compared to 13 patients (11%) for whom disease did not recur (relative risk: 3.88, P = .002). On multivariate logistic regression, hr-HPV status remained significantly predictive of disease recurrence (odds ratio: 12.3, P = .02, 95% confidence interval: 1.5–99.6). Using 2 × 2 table analysis, we found that while cervicovaginal cytology has limited specificity (5.7%) in predicting recurrence, the combination of cytology with hr-HPV testing increases the specificity of testing to 89.3%. Conclusions Persistence of hr-HPV is a risk factor for disease recurrence. High-risk–HPV testing is not routinely used during surveillance for cervical cancer, but this study suggests that large, prospective trials investigating the role of hr-HPV testing in cervical cancer surveillance are needed.

A Synopsis on the Role of Human Papilloma Virus Infection in Cervical Cancer

2018 ◽  
Vol 19 (9) ◽  
pp. 798-805 ◽  
Author(s):  
Mohd Saeed ◽  
Fawaz D. Alshammari ◽  
Md. Jahoor Alam ◽  
Khan Mohd Sarim ◽  
Khurshid Ahmad ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Virus Infection ◽  
Human Papilloma Virus ◽  
Human Papilloma Virus Infection ◽  
Papilloma Virus

scholarly journals Prostate cancer and the human papilloma virus: causative association, role of vaccines, and the impact of the COVID-19 pandemic

2021 ◽  
Author(s):  
Naomi Morka ◽  
Joseph M. Norris ◽  
Mark Emberton ◽  
Daniel Kelly
Keyword(s):  
Prostate Cancer ◽  
Human Papilloma Virus ◽  
Hpv Vaccination ◽  
Significant Proportion ◽  
Vaccine Uptake ◽  
Papilloma Virus ◽  
Vaccination Campaigns ◽  
The Impact ◽  
Hpv Vaccine Uptake

AbstractProstate cancer affects a significant proportion of men worldwide. Evidence from genetic and clinical studies suggests that there may be a causal association between prostate cancer and the human papilloma virus (HPV). As HPV is a vaccine-preventable pathogen, the possibility of a role in prostate cancer causation may reinforce the importance of effective HPV vaccination campaigns. This is of particular relevance in light of the COVID-19 pandemic, which may have considerable effects on HPV vaccine uptake and distribution.

scholarly journals Cervical pap smears and pandemics: The effect of COVID-19 on screening uptake & opportunities to improve

2021 ◽  
Vol 17 ◽  
pp. 174550652110170
Author(s):  
Hannah Masson
Keyword(s):  
Human Papilloma Virus ◽  
Cervical Screening ◽  
High Sensitivity ◽  
Health Board ◽  
Pap Smears ◽  
Local Health ◽  
Papilloma Virus ◽  
Face To Face ◽  
Screening Uptake ◽  
The Impact

Background: The Coronavirus disease 2019 (COVID-19) pandemic has led to an unprecedented upheaval within global healthcare systems and resulted in the temporary pausing of the National Health Service (NHS) Scotland Cervical Screening Programme. With several months of backlogs in appointments, there has not only been a reduction in primary samples being taken for human papilloma virus (HPV) testing but there have also been fewer women referred to colposcopy for investigation and treatment of precancerous or cancerous changes as a result. Encouraging uptake for cervical screening was always a priority before the pandemic, but it is even more important now, considering that the fears and barriers to screening that women may have are now exacerbated by COVID-19. Objectives: This article explores the impact of the pandemic on the uptake of cervical screening within NHS Ayrshire & Arran and evaluates potential strategies to improve uptake now and in future such as self-sampling and telemedicine. Methods: This article presents evidence-based literature and local health board data relating to cervical screening during the pandemic. Results: Human papilloma virus self-sampling carried out by the woman in her home has been shown to improve uptake, especially in non-attenders, whilst maintaining a high sensitivity and, crucially, reducing the need for face-to-face contact. Increased education is key to overcoming barriers women have to screening and telemedicine can strengthen engagement with women during this time. Conclusion: There are lessons to be learned from the pandemic, and we must use this opportunity to improve cervical screening uptake for the future.

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