A multimodality regimen for deep venous thrombosis prophylaxis in total knee arthroplasty

2003 ◽  
Vol 18 (2) ◽  
pp. 161-168 ◽  
Author(s):  
Richard D. Reitman ◽  
Roger H. Emerson ◽  
Linda L. Higgins ◽  
Tiffera R. Tarbox
Keyword(s):  
Total Knee Arthroplasty ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Knee Arthroplasty ◽  
Thrombosis Prophylaxis ◽  
Deep Venous Thrombosis Prophylaxis ◽  
Total Knee

scholarly journals Topical vs. intravenous administration of tranexamic acid in knee arthroplasty and prevalence of deep venous thrombosis: a randomized clinical trial

2016 ◽  
Vol 15 (2) ◽  
pp. 120-125 ◽  
Author(s):  
Ari Zekcer ◽  
Ricardo Del Priori ◽  
Clauber Tieppo ◽  
Ricardo Soares da Silva ◽  
Nilson Roberto Severino
Keyword(s):  
Total Knee Arthroplasty ◽  
Tranexamic Acid ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Intravenous Administration ◽  
Knee Arthroplasty ◽  
Duplex Ultrasound ◽  
Control Group ◽  
Perioperative Bleeding ◽  
Total Knee

Abstract Background Tranexamic acid (TXA) is widely used in orthopedic surgery to reduce perioperative bleeding. Since TXA inhibits fibrinolysis, there is concern that it may increase the risk of thromboembolic events. Objectives To verify the prevalence of deep venous thrombosis (DVT) in patients receiving TXA during total knee arthroplasty and to compare topical with intravenous administration of the drug. Methods All patients admitted for total knee arthroplasty due to primary arthrosis between June and November of 2014 were recruited consecutively. Thirty patients were randomized to a “topical group” (1.5 g TXA diluted in 50ml saline sprayed over the area operated, before tourniquet release), 30 to an “intravenous group” (20mg/kg TXA in 100 ml of saline, given at the same time as anesthesia), and 30 to a control group (100 ml of saline, given at the same time as anesthesia). All patients had duplex ultrasound scans of the legs on the 15th postoperative day. Results Deep venous thrombosis events occurred in five of the 90 patients operated (one out of 30 in the topical group [3.3%], four out of 30 in the control group [13.3%], and zero in the intravenous group). All were confirmed by duplex ultrasound scans and all were asymptomatic. Prevalence rates of DVT were similar between groups (p = 0.112 for control vs. intravenous; p = 0.353 for control vs. topical; and p =1.000 for intravenous vs. topical, according to two-sided exact tests). Conclusions Both topical and intravenous administration of TXA are safe with regard to occurrence of DVT, since the number of DVT cases in patients given TXA was not different to the number in those given placebo.

Color doppler imaging screening for deep venous thrombosis in total knee arthroplasty: Our two year reassessment of the learning curve

1998 ◽  
Vol 13 (2) ◽  
pp. 237
Author(s):  
Geoffrey H. Westrich ◽  
Scott J. Tarantino ◽  
Bernard Ghelman ◽  
Robert Schneider ◽  
Thomas P. Sculco ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Learning Curve ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Knee Arthroplasty ◽  
Color Doppler ◽  
Color Doppler Imaging ◽  
Doppler Imaging ◽  
Total Knee

Ultrasound Screening for Deep Venous Thrombosis After Total Knee Arthroplasty

1998 ◽  
Vol 356 ◽  
pp. 125-133 ◽  
Author(s):  
Geoffrey H. Westrich ◽  
Melissa L. Allen ◽  
Scott J. Tarantino ◽  
Bernard Ghelman ◽  
Robert Schneider ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Knee Arthroplasty ◽  
Ultrasound Screening ◽  
Total Knee

Disease-specific screening for deep venous thrombosis and pulmonary thromboembolism using plasma d-dimer values after total knee arthroplasty

2008 ◽  
Vol 18 (4) ◽  
pp. 359-365 ◽  
Author(s):  
Teruhito Yoshitaka ◽  
Nobuhiro Abe ◽  
Hiroshi Minagawa ◽  
Hirokazu Date ◽  
Yoshimasa Sakoma ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Knee Arthroplasty ◽  
Pulmonary Thromboembolism ◽  
Total Knee ◽  
Disease Specific ◽  
D Dimer

Deep Venous Thrombosis After Total Hip or Total Knee Arthroplasty in Patients in Japan

2000 ◽  
Vol 375 ◽  
pp. 168-174 ◽  
Author(s):  
Satoru Fujita ◽  
Shigeaki Hirota ◽  
Takenori Oda ◽  
Yasuji Kato ◽  
Yasunori Tsukamoto ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Knee Arthroplasty ◽  
Total Hip ◽  
Total Knee
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