Prostaglandin inhibitors as tocolytic agents

2001 ◽  
Vol 25 (4) ◽  
pp. 256-262 ◽  
Author(s):  
Stephen T. Vermillion ◽  
Charles N. Landen
Keyword(s):  
Prostaglandin Inhibitors ◽  
Tocolytic Agents

Premature birth (Clinical lecture)

2018 ◽  
pp. 9-12
Author(s):  
I.B. Ventskovskaya ◽  
◽  
V.V. Bila ◽  
O.S. Countryside ◽  
◽  
...  
Keyword(s):  
Magnesium Sulfate ◽  
Key Words ◽  
Gestational Age ◽  
Evidence Based Medicine ◽  
Premature Birth ◽  
Preterm Labor ◽  
Evidence Based ◽  
Advantages And Disadvantages ◽  
Based Medicine ◽  
Tocolytic Agents

The article presents modern views on the pathogenesis of preterm labor, their relevance and classification. From the perspective of evidence-based medicine methods of prevention are considered. A comparison of the main tocolytic agents, their advantages and disadvantages is presented. Key words: premature birth, perinatal and infantile mortality, tocolysis, magnesium sulfate, gestational age.

Efficacy and side effects of magnesium sulfate and ritodrine as tocolytic agents

1988 ◽  
Vol 159 (3) ◽  
pp. 685-689 ◽  
Author(s):  
Isabelle A. Wilkins ◽  
Lauren Lynch ◽  
Karen E. Mehalek ◽  
Gertrud S. Berkowitz ◽  
Richard L. Berkowitz
Keyword(s):  
Side Effects ◽  
Magnesium Sulfate ◽  
Tocolytic Agents

External Cephalic Version at Term with Tocolysis

1988 ◽  
Vol 18 (3) ◽  
pp. 119-124 ◽  
Author(s):  
G Justus Hofmeyr
Keyword(s):  
Developing Countries ◽  
Caesarean Section ◽  
Breech Presentation ◽  
External Cephalic Version ◽  
Cephalopelvic Disproportion ◽  
Breech Delivery ◽  
Vaginal Breech Delivery ◽  
High Prevalence ◽  
Large Families ◽  
Tocolytic Agents

The problems associated with breech presentation are of particular importance in developing countries. The risk of vaginal breech delivery may be increased because of a high prevalence of cephalopelvic disproportion. Caesarean section presents specific risks to women who may not have medical care in subsequent pregnancies and may desire large families. External cephalic version (ECV) before term has not been proved conclusively to influence the outcome of pregnancy. ECV performed at term (37 or more weeks gestation), using tocolytic agents to relax the uterus, has been shown in a technologically developed setting to reduce the incidence of breech presentation and of Caesarean section. The application of this procedure when technological facilities are limited is discussed and the technique is described.

PROSTAGLANDIN INHIBITORS AND GASTRIC FACTORS IN MIGRAINE

The Lancet ◽  
1980 ◽  
Vol 315 (8172) ◽  
pp. 832-833 ◽  
Author(s):  
J PARANTAINEN
Keyword(s):  
Prostaglandin Inhibitors

scholarly journals Comparative study of efficacy of nifedipine, nitroglycerin dermal patches and isoxsuprine as tocolytic agents in suppression of preterm labour 1-year study at navodaya medical college hospital and research centre Raichur

2021 ◽  
Vol 10 (7) ◽  
pp. 2806
Author(s):  
Rita D. ◽  
V. Haripriya
Keyword(s):  
Side Effects ◽  
Preterm Labour ◽  
Research Centre ◽  
College Hospital ◽  
Treatment Groups ◽  
Medical College ◽  
Uterine Contractions ◽  
Significant Difference ◽  
Tocolytic Agent ◽  
Tocolytic Agents

Background: Tocolytic agents are used to reduce preterm deliveries. Very few studies documenting the comparison of tocolytic agents viz. nifedipine, nitroglycerin dermal patches and isoxsuprine. Other drugs are not used due to their adverse effects. Objective was to study and compare the safety efficacy of nifedipine, nitroglycerin dermal patches and isoxsuprine as tocolytic agents in suppression of preterm labour 1 year study.Methods: This was a prospective case control study was conducted for a period of 1 year. Total 90 cases selected to study were randomly distribute in to three treatment groups viz. A, B, and C nifedipine, nitroglycerin and isoxsuprine respectively. Subjects in all three groups were evaluated for maternal pulse rate, palpitation uterine contractions and fetal heart rate in order to assess efficacy of each drug under investigation.Results: There was no statistically significant difference in age of woman’s in three different groups. Among (100%) subjects, majority of the cases i.e. (27.8%) primi gravida followed by multi (72.2%). Side effects of nifedipine was less when compared to nitroglycerine dermal patch and isoxsuprine i/v/o of headache (8.9%), nausea (1.1%), vomiting (1.1%), tachycardia (3.3%), palpitation (3.3%), hypotension (1.1%). side effects were statistically significant different between the treatment groups. There was no statistically significant difference with respect to APGAR score at 1 minute and 5 minutes.Conclusions: Oral nifedipine was found to be superior and efficacious as tocolytic agent as compared to transdermal nitroglycerin and intravenous isoxsuprine.

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