Cause and management of heart failure in patients with chronic renal disease

2001 ◽  
Vol 21 (1) ◽  
pp. 3-12 ◽  
Author(s):  
Amin Al-Ahmad ◽  
Mark J. Sarnak ◽  
Deeb N. Salem ◽  
Marvin A. Konstam
Keyword(s):  
Heart Failure ◽  
Renal Disease ◽  
Chronic Renal Disease

Population-Based Analysis of Late Cardiovascular Morbidity and Hospitalizations After Hematopoietic Cell Transplantation.

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 517-517
Author(s):  
Eric J Chow ◽  
K. Scott Baker ◽  
Debra L. Friedman ◽  
Kara Cushing-Haugen ◽  
Mary E.D. Flowers ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Disease ◽  
Renal Disease ◽  
Hospital Discharge ◽  
Hematopoietic Cell Transplantation ◽  
Comparison Group ◽  
Chronic Renal Disease ◽  
Younger Age ◽  
Increased Risk ◽  
Driver's License

Abstract Abstract 517 BACKGROUND: There is growing evidence that recipients of hematopoietic cell transplantation (HCT) have increased risk of adverse long-term effects such as hypertension, dyslipidemia, and diabetes which may contribute to increased cardiovascular (CV) morbidity and mortality. METHODS: The Fred Hutchinson Cancer Research Center (FHCRC) performs the vast majority of HCTs in Washington State. We linked the medical records of all 2-year HCT survivors who were state residents treated at FHCRC from 1985-2005 (n=1405; 62% allogeneic; 38% autologous) to the state's hospital discharge and death registries beginning 2 years after HCT. Individuals randomly selected from state driver's license files (n=5964) served as a comparison group, frequency-matched by age, sex, and county of residence. Selected serious CV diagnoses (ischemic heart disease, dysrhythmia, cardiomyopathy/heart failure, stroke and other vascular disease) and related diseases (dyslipidemia, diabetes, chronic renal disease) were identified from these databases for the HCT and comparison cohorts. Odds ratio (OR) estimates of the relative risk were calculated using logistic regression adjusted for age and year of HCT/driver's license filing, sex, and race/ethnicity (HCT patients only). RESULTS: With a median age at HCT of 40 (0-73) years and follow-up time of 5 (2-22) years since HCT, survivors were significantly more likely to have subsequent CV and related diagnoses recorded in hospital discharge (28% vs. 10%; p<0.01) and death records (4% vs. 1%; p<0.01) vs. the comparison group. In particular, dysrhythmia, cardiomyopathy/heart failure, stroke and other vascular diseases, diabetes, and chronic renal disease were recorded more frequently among the HCT cohort. Rates of ischemic heart disease were not significantly different between the 2 groups (4% vs. 3%; p=0.14). In multivariable analyses, factors independently associated with increased CV hospitalizations included history of chronic graft vs. host disease (OR 2.0 [1.4-2.7]) and receiving >1 HCT of any type (OR 2.1 [1.4-3.0]). Receiving >1 HCT also was associated with statistically significant 2-3 fold increased risks of dysrhythmia, cardiomyopathy/heart failure, and chronic renal disease. Allogeneic transplants and preparative regimens containing total body irradiation (TBI) were not associated with an increased risk of CV hospitalization compared with autologous transplants and non-TBI containing regimens, respectively. While older age at baseline was associated with an increased risk of most CV outcomes in both groups, in age-stratified analysis, those who received HCT at a younger age had the greatest risk vs. similar-aged comparison subjects (e.g. <20 years at HCT, CV hospitalization OR=37.8 [16.5-86.2]; ≥60 years at HCT, OR=1.7 [1.1-2.6]). In contrast to the comparison group, among HCT survivors increased body mass index was not consistently associated with an increased risk of CV outcomes except for diabetes. CONCLUSIONS: CV-related hospitalizations and deaths occurred significantly more often among 2-year HCT survivors than the comparison group, as measured by hospital discharge and death registries. Similar risk was observed following allogeneic and autologous transplants. Patients who received HCT at a younger age and those who experienced multiple transplants of any type were at particularly increased risk. To more completely delineate risk factors, future analyses will examine the effects of pre-HCT anthracycline and chest radiotherapy exposures, and elapsed time since HCT. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Long-Term Survival and Medical Costs of Patients with Prolonged Mechanical Ventilation and Tracheostomy: A Nationwide Cohort Study

2021 ◽  
Vol 18 (19) ◽  
pp. 10272
Author(s):  
Hui-Hsuan Lai ◽  
Pei-Ying Tseng ◽  
Chen-Yu Wang ◽  
Jong-Yi Wang
Keyword(s):  
Heart Failure ◽  
Mechanical Ventilation ◽  
Chronic Heart Failure ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Prolonged Mechanical Ventilation ◽  
Medical Expenditures ◽  
Research Database ◽  
Long Term Mortality

Few large-scale studies have focused on tracheostomy in patients with prolonged mechanical ventilation. This retrospective population-based study extracted data from the longitudinal National Health Insurance Research Database in Taiwan to compare long-term mortality between patients on prolonged mechanical ventilation with and without tracheostomy and their related medical expenditures. Data on newly developed respiratory failure in patients on ventilator support were extracted from 1 January 2002 to 31 December 2008. Of 10,705 patients included, 1372 underwent tracheostomy (n = 563) or translaryngeal intubation (n = 779). Overall survival of the patients with tracheostomy was followed for 5 years. Average survival was 4.98 years for the patients with tracheostomy and 5.48 years for the patients with translaryngeal intubation (not significant). Sex, age, premium-based monthly salary difference, occupation, urbanization level, chronic obstructive pulmonary disease, chronic heart failure, chronic renal disease, and cerebrovascular diseases were significantly associated with mortality for endotracheal intubation. Male sex, chronic heart failure, chronic renal disease, age ≥45 years, and low income were associated with significantly higher mortality. Although total medical expenditures were higher for the patients with tracheostomy, annual medical expenditures were not significantly different. There were no differences in long-term mortality between the two groups.

The association between congestive heart failure and chronic renal disease

2004 ◽  
Vol 13 (2) ◽  
pp. 163-170 ◽  
Author(s):  
Donald Silverberg ◽  
Dov Wexler ◽  
Miriam Blum ◽  
Doron Schwartz ◽  
Adrian Iaina
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Renal Disease ◽  
Chronic Renal Disease

scholarly journals Anemia, chronic renal disease and chronic heart failure: the cardiorenal anemia syndrome

2008 ◽  
Vol 10 (4) ◽  
pp. 189-196 ◽  
Author(s):  
DONALD S. SILVERBERG ◽  
DOV WEXLER ◽  
ADRIAN IAINA ◽  
DORON SCHWARTZ
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Renal Disease ◽  
Chronic Renal Disease
Sign in / Sign up

Export Citation Format

Share Document