Calculation of urinary enzyme excretion, with renal structure and function in dogs with pyometra

2001 ◽  
Vol 70 (2) ◽  
pp. 129-137 ◽  
Author(s):  
R. HEIENE ◽  
L. MOE ◽  
G. MØLMEN
Keyword(s):  
Structure And Function ◽  
Urinary Enzyme ◽  
Renal Structure ◽  
And Function ◽  
Urinary Enzyme Excretion

Discordant effects of guanidines on renal structure and function and on regional vascular dysfunction and collagen changes in diabetic rats

Diabetes ◽  
1997 ◽  
Vol 46 (1) ◽  
pp. 94-106 ◽  
Author(s):  
J. R. Nyengaard ◽  
K. Chang ◽  
S. Berhorst ◽  
K. M. Reiser ◽  
J. R. Williamson ◽  
...  
Keyword(s):  
Vascular Dysfunction ◽  
Diabetic Rats ◽  
Structure And Function ◽  
Renal Structure ◽  
And Function

scholarly journals Radix Rehmanniae and Corni Fructus against Diabetic Nephropathy via AGE-RAGE Signaling Pathway

2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Jing Chen ◽  
Yuping Chen ◽  
Anmei Shu ◽  
Jinfu Lu ◽  
Qiu Du ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Signaling Pathway ◽  
Animal Experiments ◽  
Structure And Function ◽  
Metabolic Parameters ◽  
Network Pharmacology ◽  
Active Compounds ◽  
Renal Structure ◽  
Corni Fructus ◽  
And Function

Background and Aims. Radix Rehmanniae and Corni Fructus (RC) have been widely applied to treat diabetic nephropathy (DN) for centuries. But the mechanism of how RC plays the therapeutic role against DN is unclear as yet. Methods. The information about RC was obtained from a public database. The active compounds of RC were screened by oral bioavailability (OB) and drug-likeness (DL). Gene ontology (GO) analysis was performed to realize the key targets of RC, and an active compound-potential target network was created. The therapeutic effects of RC active compounds and their key signal pathways were preliminarily probed via network pharmacology analysis and animal experiments. Results. In this study, 29 active compounds from RC and 64 key targets related to DN were collected using the network pharmacology method. The pathway enrichment analysis showed that RC regulated advanced glycosylation end product (AGE-) RAGE and IL-17 signaling pathways to treat DN. The animal experiments revealed that RC significantly improved metabolic parameters, inflammation renal structure, and function to protect the kidney against DN. Conclusions. The results revealed the relationship between multicomponents and multitargets of RC. The administratiom of RC might remit the DM-induced renal damage through the AGE-RAGE signaling pathway to improve metabolic parameters and protect renal structure and function.

Renal structure and function in insulin-dependent diabetes mellitus in man

1992 ◽  
Vol 10 (Supplement 1) ◽  
pp. S17-S20 ◽  
Author(s):  
S Michael Mauer ◽  
Pascale Lane ◽  
Dan Zhu ◽  
Paola Fioretto ◽  
Michael W. Steffes
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Dependent Diabetes Mellitus ◽  
Structure And Function ◽  
Insulin Dependent Diabetes ◽  
Dependent Diabetes Mellitus ◽  
Renal Structure ◽  
Insulin Dependent ◽  
And Function

Response to: De Novo Kidney Transplantation Without Use of Calcineurin Inhibitors Preserves Renal Structure and Function at 2 Years

2005 ◽  
Vol 5 (5) ◽  
pp. 1169-1169
Author(s):  
Stuart M. Flechner ◽  
Caroline M. Lanigan ◽  
Daniel R. Salomon ◽  
James T. Burke ◽  
Kim Solez
Keyword(s):  
Kidney Transplantation ◽  
De Novo ◽  
Calcineurin Inhibitors ◽  
Structure And Function ◽  
Renal Structure ◽  
And Function
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