Secretion of Interleukin-1β and Interleukin-6 by Fragments of Term Human Placental Villi: Signalling Pathways and Effects of Tumour Necrosis Factor α and Mode of Delivery

Placenta ◽  
2002 ◽  
Vol 23 (6) ◽  
pp. 467-474 ◽  
Author(s):  
M.A. Turner ◽  
S.A. Shaikh ◽  
S.L. Greenwood
Keyword(s):  
Tumour Necrosis Factor ◽  
Interleukin 6 ◽  
Tumour Necrosis ◽  
Mode Of Delivery ◽  
Interleukin 1Β ◽  
Signalling Pathways ◽  
Tumour Necrosis Factor Α ◽  
Placental Villi ◽  
Factor Α ◽  
Necrosis Factor

Influence of l-glutamic acid on binding of interleukin-1β, tumour necrosis factor-α and interleukin-6 to HL-60 cells

1998 ◽  
Vol 62 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Irina A Kostanyan ◽  
Rosa I Nurieva ◽  
Elena V Navolotskaya ◽  
Maria V Astapova ◽  
Svetlana M Dranitsina ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Tumour Necrosis Factor ◽  
Interleukin 6 ◽  
Tumour Necrosis ◽  
Interleukin 1Β ◽  
Tumour Necrosis Factor Α ◽  
Factor Α ◽  
Necrosis Factor

Tumour necrosis factor-α, interleukin-1β and interleukin-6 in patients with renal cell carcinoma

1994 ◽  
Vol 30 (2) ◽  
pp. 162-167 ◽  
Author(s):  
Christine Dosquet ◽  
Antoine Schaetz ◽  
Claire Faucher ◽  
Eric Lepage ◽  
Jean-Luc Wautier ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Tumour Necrosis Factor ◽  
Interleukin 6 ◽  
Renal Cell ◽  
Tumour Necrosis ◽  
Interleukin 1Β ◽  
Tumour Necrosis Factor Α ◽  
Factor Α ◽  
Necrosis Factor

Interleukin 1β and tumour necrosis factor α stimulate the release of gonadotropin-releasing hormone and interleukin 6 by primary cultured rat hypothalamic cells

1990 ◽  
Vol 123 (5) ◽  
pp. 476-480 ◽  
Author(s):  
Masaaki Yamaguchi ◽  
Yasuhiro Yoshimoto ◽  
Hiroko Komura ◽  
Koji Koike ◽  
Noboru Matsuzaki ◽  
...  
Keyword(s):  
Tumour Necrosis Factor ◽  
Interleukin 6 ◽  
Tumour Necrosis ◽  
Interleukin 1Β ◽  
Tumour Necrosis Factor Α ◽  
Gnrh Secretion ◽  
Significant Stimulation ◽  
Hypothalamic Cells ◽  
Factor Α ◽  
Necrosis Factor

Abstract. The abilities of recombinant human interleukin 1β and tumour necrosis factor α to induce release of GnRH and interleukin 6 from primary culture of rat hypothalamic cells were examined. The effect of estradiol on the release of interleukin 6 by these cells was also tested. Both interleukin 1β and tumour necrosis factor α caused significant stimulation of GnRH secretion from the hypothalamic cells within 5 min. The hypothalamic cells secreted interleukin 6 spontaneously, and their secretion over 24 h was stimulated dose-dependently by interleukin 1β, tumour necrosis factor α and estradiol. These results suggest that interleukin 1β and tumour necrosis factor α stimulate the secretions of GnRH and interleukin 6 in the hypothalamus, and that these cytokines may be involved in the mechanism of GnRH secretion in the hypothalamus.

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