Cardiovascular risk factors in men: The role of gonadal steroids and sex hormone-binding globulin

Metabolism ◽  
2001 ◽  
Vol 50 (8) ◽  
pp. 882-888 ◽  
Author(s):  
Jesper Gyllenborg ◽  
Susanne L. Rasmussen ◽  
Knut Borch-Johnsen ◽  
Berit L. Heitmann ◽  
Niels E. Skakkeb[aelig ]k ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Sex Hormone ◽  
Gonadal Steroids ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding

scholarly journals Relationship between serum leptin levels, non-cardiovascular risk factors and mortality in hemodialysis patients

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Ivona Risovic ◽  
Vlastimir Vlatkovic ◽  
Snjezana Popovicpejicic ◽  
Gabrijela Malešević
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Survival Rates ◽  
Inverse Correlation ◽  
Study Groups ◽  
Mineral And Bone Disorder ◽  
Serum Leptin ◽  
Significant Difference

Abstract Introduction. Hemodialysis (HD) patients have higher mortality rate than the general population. Recent studies indicate a significant role of non-cardiovascular risk factors in for mortality in HD patients. Leptin is protein hormone and may indicate malnutrition in HD patients. Its role in mortality in these patients is being examined. This study aimed to investigate the correlation between serum leptin levels and non-cardiovascular risk factors and relationship between leptin level and mortality in HD patients. Methods The prospective study included 93 patients on maintenance HD and follow-up period was 12 months. We measured leptin level and evaluated non-cardiovascular risk factors: nutritional status, anemia, volemia, parameters of mineral and bone disorder. Results. Out of 93 patients 9 died during study and 1 underwent kidney transplantation. Malnutrition and hypervolemia were two main non-cardiovascular risk factors among deceased subjects. Leptin showed a significant direct correlation with nutritional BMI (r = 0.72, P <0.001), fat tissue index (r = 0.74, P <0.001) and statistically significant inverse correlation with leantissue index (r = -0.349, P <0.05) and inverse correlation with volemic parameters (overhydration / extracellular water ratio (r = -0.38, P <0.001), but no association with anemia and mineral bone parameters was observed. Elevated leptin levels were associated with better survival. However, no statistically significant difference in survival rates was observed between the study groups (Log-Rank P =0.214, Breslow P =0.211, Tarone-Ware P=0.212). Conclusion: Deceased patients had significantly lower leptin values. Leptin was associated with two non-cardiovascular risk factors for mortality: malnutrition and hypervolemia.

scholarly journals Role of green tea in reduction of cardiovascular risk factors

2010 ◽  
pp. 85
Author(s):  
Charalambos Vlachopoulos ◽  
Alexopoulos ◽  
Stefanadis
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Green Tea

Role of the Ovary in the Regulation of Sex Hormone Binding Globulin and Its Contribution to Peripheral Levels of Androstenedione

2009 ◽  
Vol 82 (04) ◽  
pp. 29-34 ◽  
Author(s):  
P. Bolufer ◽  
P. Antonio ◽  
R. Garcia ◽  
J. Munoz ◽  
A. Rodriguez ◽  
...  
Keyword(s):  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding
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