Assessing systemic 11[beta ]-hydroxysteroid dehydrogenase with serum cortisone/cortisol ratios in healthy subjects and patients with diabetes mellitus and chronic renal failure

Metabolism ◽  
2001 ◽  
Vol 50 (7) ◽  
pp. 801-804 ◽  
Author(s):  
Masato Homma ◽  
Akihisa Tanaka ◽  
Kumiko Hino ◽  
Hiroe Takamura ◽  
Toshihiko Hirano ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Healthy Subjects ◽  
Hydroxysteroid Dehydrogenase ◽  
Patients With Diabetes

scholarly journals The Study of Biochemical Markers in Chronic Renal Failure Patients in Pre- and Post-Haemodialysis

2021 ◽  
Vol 53 (03) ◽  
pp. 259-264
Author(s):  
Mohammed Abed Jawad ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Lipid Peroxidation ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Group Method ◽  
Control Group ◽  
Renal Markers ◽  
Patients With Diabetes ◽  
History Of ◽  
Notable Increase

Background: The current research is designed to investigate alterations in lipid peroxidation (malondialdehyde - MDA) and renal markers (urea and creatinine) in patients of chronic renal failure (CRF) as compared to the control group. Method: The study included 55 subjects, who were separated into two groups: control group, which included 15 healthy members with no history of systematic illness; and patients group, which included 40 patients with CRF divided into four groups “Non: CRF patients without any accompanied disease, DM: CRF patients with diabetes mellitus, HT: CRF patients with hypertension, and HT + DM: CRF patients with diabetes mellitus and hypertension”. Results: The findings reveal that there is a notable increase in serum concentration of MDA, urea, and creatinine, in patients group as compared to the control group. Conclusion: In all chronic renal failure patients with or without any accompanying disease, lipid peroxidation is present in pre- and post-haemodialysis patients as well as patients with CRF have high levels of urea and creatinine compared with healthy groups.

scholarly journals ALBUMIN AND HEMOGLOBIN VALUE IN CHRONIC RENAL FAILURE (CRF) PATIENTS WITH DIABETES AND NON-DIABETES

2018 ◽  
Vol 2 (2) ◽  
pp. 253
Author(s):  
Diyah Candra Anita
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Nutritional Status ◽  
Sampling Method ◽  
Historical Background ◽  
Measuring Instruments ◽  
Cross Sectional ◽  
Patients With Diabetes ◽  
Larger Sample

Introduction. Malnutrition is a common problem in patients with chronic renal failure (CRF) with Diabetes Mellitus and Non-Diabetes Mellitus. Assessments of nutritional status in CRF patients are required to measure some important parameters including serum albumin and hemoglobin. This study aimed to fi gure out the differences of nutritional status between CRF patients with diabetes mellitus and without diabetes mellitus in the inpatient unit of PKU Muhammadiyah Hospital Yogyakarta, by examining the levels of albumin and hemoglobin serum. Methods. This study applied cross sectional method of which measuring instruments were patients’ medical records of laboratory tests. This research used accidental sampling method involving 30 patients as samples. Result. The results of independent t-test showed that there was no signifi cant differences between the levels of albumin (p = 0.917) and hemoglobin (p = 0.168) between the group of non DM CRF patients and CRF patients with  M. Discussion. Therefore, further research should be performed by using a larger sample size as well as considering patients’ historical background of hemodialysis treatment.Keywords: Diabetes Mellitus (DM), Chronic Renal Failure (CRF), albumin, hemoglobin

scholarly journals Differences in Arteriovenous Fistula Maturation between Diabetes Mellitus and Non-Diabetes Mellitus in Chronic Renal Failure Patients in Padang

2021 ◽  
Vol 6 (1) ◽  
pp. 1287-1291
Author(s):  
Richard Santosa ◽  
Raflis Rustam ◽  
Vendry Rivaldy
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Arteriovenous Fistula ◽  
Kidney Failure ◽  
Chronic Kidney Failure ◽  
Fistula Surgery ◽  
Arteriovenous Fistulas ◽  
Significant Difference ◽  
Patients With Diabetes

Background: Arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis (HD). Several factors can affect AVF maturity, such as diabetes. This study aims to determine the differences in the maturation of arteriovenous fistulas between diabetes mellitus and non-diabetes mellitus in patients with chronic kidney failure in Padang. Methods: This was a comparative cross-sectional study of patients with chronic kidney failure who underwent arteriovenous fistula surgery in Padang. The sampling technique in this study was consecutive sampling. The analysis was carried out using statistical analysis according to the existing data scale and using SPSS software. Results: This study involved 46 patients with chronic kidney failure who underwent arteriovenous fistula surgery in Padang, of which 23 patients with diabetes mellitus and 23 patients with non-diabetes mellitus. The diameter of the arteriovenous fistula between diabetes mellitus and non-diabetes mellitus in patients with chronic renal failure had a significant difference (p<0.05). There was no significant difference in flow, depth, and maturation of arteriovenous fistulas in patients with diabetes mellitus and non-diabetes mellitus with chronic renal failure. Conclusion: There is no difference in the maturation of arteriovenous fistula between patients with diabetes mellitus and non-diabetes mellitus

STATUS NUTRISI PASIEN GAGAL GINJAL KRONIS DENGAN DIABETES MELLITUS DAN NON-DIABETES MELLITUS

2016 ◽  
Vol 5 (2) ◽  
pp. 92-98
Author(s):  
Diyah Candra Anita
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Nutritional Status ◽  
Medical Records ◽  
Descriptive Research ◽  
Measuring Devices ◽  
Laboratory Results ◽  
Patients With Diabetes ◽  
Test Result

Background:Malnutrition is a common problem in chronic renal failure (CRF) patients with or without Diabetes Mellitus (DM). An assessment of nutritional status in CRF patients is encouraged to see the level of its severity. The general parameters for assessing nutritional status are serum albumin and hemoglobin. Objective:The objective of this research was to investigate the differences on thenutritional status of CRF patients with Diabetes Mellitus (DM) compared to those without DM at PKU Muhammadiyah Hospital Yogyakarta. Methods:This was a comparative descriptive research applying accidental sampling and was conducted for 6 months (June-November 2014). The main measuring devices were patients’ medical records and laboratory results of albumin and hemoglobin levels. Sampleof this study consisted of 30 respondents. Independent t-test was applied to analyze the differences of albumin and hemoglobin levels in both groups. Result:The test result showed that the albumin (p=0.917) and hemoglobin levels (p=0.168) of CRF patients without DM and that of CRF patients with DM were not significantly different. Conclusion:CRF patients with and without DM had low level of albumin and hemoglobin. Nurses shouldbe more careful in regulating fluidbalance to reduce pulmonary edema. Keywords:Chronic Renal Failure (CRF), diabetes mellitus(DM), albumin, hemoglobin

scholarly journals STATUS NUTRISI PASIEN GAGAL GINJAL KRONIS DENGAN DIABETES MELLITUS DAN NON-DIABETES MELLITUS

2019 ◽  
Vol 5 (2) ◽  
pp. 92-98
Author(s):  
Diyah Candra Anita
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Nutritional Status ◽  
Medical Records ◽  
Descriptive Research ◽  
Measuring Devices ◽  
Laboratory Results ◽  
Patients With Diabetes ◽  
Test Result

Background:Malnutrition is a common problem in chronic renal failure (CRF) patients with or without Diabetes Mellitus (DM). An assessment of nutritional status in CRF patients is encouraged to see the level of its severity. The general parameters for assessing nutritional status are serum albumin and hemoglobin. Objective:The objective of this research was to investigate the differences on thenutritional status of CRF patients with Diabetes Mellitus (DM) compared to those without DM at PKU Muhammadiyah Hospital Yogyakarta. Methods:This was a comparative descriptive research applying accidental sampling and was conducted for 6 months (June-November 2014). The main measuring devices were patients’ medical records and laboratory results of albumin and hemoglobin levels. Sampleof this study consisted of 30 respondents. Independent t-test was applied to analyze the differences of albumin and hemoglobin levels in both groups. Result:The test result showed that the albumin (p=0.917) and hemoglobin levels (p=0.168) of CRF patients without DM and that of CRF patients with DM were not significantly different. Conclusion:CRF patients with and without DM had low level of albumin and hemoglobin. Nurses shouldbe more careful in regulating fluidbalance to reduce pulmonary edema. Keywords: Chronic Renal Failure (CRF), diabetes mellitus(DM), albumin, hemoglobin

scholarly journals Treatment of arterial hypertension in patients with diabetes mellitus and nephropathy: current potentialities of renin-angiotensin-aldosterone system block

2003 ◽  
Vol 9 (6) ◽  
pp. 191-195
Author(s):  
O. D. Ostroumova ◽  
A. A. Zykova ◽  
A. M. Batutina
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Arterial Hypertension ◽  
Antihypertensive Agents ◽  
Cardiovascular Complications ◽  
Angiotensin Ii Receptor ◽  
Hypertensive Nephropathy ◽  
Patients With Diabetes ◽  
End Stage

Diabetes mellitus and arterial hypertension are major risk factors of cardiovascular complications. Diabetic nephropathy is the most common cause of end-stage chronic renal failure in the world; next is hypertensive nephropathy. Microalbuminuria is the earliest clinical marker of renal dysfunction. The basic clinical significance of microalbuminuria is that it is an independent risk factor of both end-stage chronic renal failure and cardiovascular complications. Controlling blood pressure with antihypertensive agents in patients with diabetes mellitus ensures diminished microalbuminuria and retards the development of chronic renal failure. Angiotensin II receptor blockers and angiotensin-converting enzyme (ACE) inhibitors are essential drugs for the treatment of patients with diabetes mellitus and nephropathy. A combination of these two classes of drugs offers new prospects for nephroprotection in this group of patients.

Enzyme immunoassay of hemoglobin A1c: analytical characteristics and clinical performance for patients with diabetes mellitus, with and without uremia.

1989 ◽  
Vol 35 (1) ◽  
pp. 93-97 ◽  
Author(s):  
F Engbaek ◽  
S E Christensen ◽  
B Jespersen
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Enzyme Immunoassay ◽  
Hemoglobin A1c ◽  
Clinical Performance ◽  
Fetal Hemoglobin ◽  
Reference Interval ◽  
Diabetic Patients ◽  
Patients With Diabetes

Abstract We evaluated an enzyme immunoassay (Novo BioLabs) for determination of hemoglobin A1c and measured the contribution of carbamylated hemoglobin to the hemoglobin A1c results obtained by HPLC for patients with chronic renal failure. The reference interval, determined for blood donors, was 0.035-0.050 (i.e., 3.5% to 5% of the total hemoglobin). For non-diabetic patients with chronic renal failure, on hemodialysis, the mean proportion of hemoglobin A1c was 0.038 (SD 0.0045); for umbilical cord blood it was 0.006-0.009. For diabetic patients with normal or near-normal renal function, results by enzyme immunoassay (y) and HPLC (x) correlated well (r = 0.83): y = 0.99x - 0.005. Added fetal hemoglobin or carbamylated hemoglobin did not interfere with enzyme immunoassay, but added carbamylated hemoglobin co-chromatographed with hemoglobin A1c. Measurements for patients with chronic renal failure, with or without diabetes, by enzyme immunoassay and by HPLC, were compared with measurements for patients with diabetes mellitus but no renal failure. Carbamylated hemoglobin contributed 0.019 to the hemoglobin A1c results obtained by HPLC for patients with chronic renal failure.

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