scholarly journals Hepatitis C virus core protein induces apoptosis and impairs cell-cycle regulation in stably transformed chinese hamster ovary cells

Hepatology ◽  
2000 ◽  
Vol 31 (6) ◽  
pp. 1351-1359 ◽  
Author(s):  
Masao Honda ◽  
Shuichi Kaneko ◽  
Takeo Shimazaki ◽  
Eiki Matsushita ◽  
Kenichi Kobayashi ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Cell Cycle Regulation ◽  
Core Protein ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells ◽  
Virus Core ◽  
Cycle Regulation

Cell cycle regulation of hepatitis C virus internal ribosomal entry site–directed translation

2000 ◽  
Vol 118 (1) ◽  
pp. 152-162 ◽  
Author(s):  
Masao Honda ◽  
Shuichi Kaneko ◽  
Eiki Matsushita ◽  
Kenichi Kobayashi ◽  
Geoffrey A. Abell ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Cell Cycle Regulation ◽  
Internal Ribosomal Entry Site ◽  
Entry Site ◽  
Ribosomal Entry ◽  
Cycle Regulation

scholarly journals Cell cycle regulation of the c-Myc transcriptional activation domain

1993 ◽  
Vol 13 (7) ◽  
pp. 4125-4136
Author(s):  
A Seth ◽  
S Gupta ◽  
R J Davis
Keyword(s):  
Cell Cycle ◽  
Dna Binding ◽  
Transcriptional Activation ◽  
Cell Cycle Regulation ◽  
Cell Cycle Progression ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Transactivation Domain ◽  
Transcriptional Activation Domain ◽  
Cycle Regulation

The product of the c-myc gene (c-Myc) is a sequence-specific DNA-binding protein that has previously been demonstrated to be required for cell cycle progression. Here we report that the c-Myc DNA binding site confers cell cycle regulation to a reporter gene in Chinese hamster ovary cells. The observed transactivation was biphasic with a small increase in G1 and a marked increase during the S-to-G2/M transition of the cell cycle. This cell cycle regulation of transactivation potential is accounted for, in part, by regulatory phosphorylation of the c-Myc transactivation domain. Together, these data demonstrate that c-Myc may have an important role in the progression of cells through both the G1 and G2 phases of the cell cycle.

scholarly journals Cell cycle regulation of the c-Myc transcriptional activation domain.

1993 ◽  
Vol 13 (7) ◽  
pp. 4125-4136 ◽  
Author(s):  
A Seth ◽  
S Gupta ◽  
R J Davis
Keyword(s):  
Cell Cycle ◽  
Dna Binding ◽  
Transcriptional Activation ◽  
Cell Cycle Regulation ◽  
Cell Cycle Progression ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Transactivation Domain ◽  
Transcriptional Activation Domain ◽  
Cycle Regulation

The product of the c-myc gene (c-Myc) is a sequence-specific DNA-binding protein that has previously been demonstrated to be required for cell cycle progression. Here we report that the c-Myc DNA binding site confers cell cycle regulation to a reporter gene in Chinese hamster ovary cells. The observed transactivation was biphasic with a small increase in G1 and a marked increase during the S-to-G2/M transition of the cell cycle. This cell cycle regulation of transactivation potential is accounted for, in part, by regulatory phosphorylation of the c-Myc transactivation domain. Together, these data demonstrate that c-Myc may have an important role in the progression of cells through both the G1 and G2 phases of the cell cycle.

scholarly journals Up-regulating effect of hepatitis C virus core protein on expression of cell cycle gene Wee1

2003 ◽  
Vol 11 (7) ◽  
pp. 947-950
Author(s):  
Jian-Jun Wang ◽  
Yan Liu ◽  
Jun Cheng ◽  
Qian Yang ◽  
Yan-Jie Yang
Keyword(s):  
Cell Cycle ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Core Protein ◽  
Cell Cycle Gene ◽  
Virus Core
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