scholarly journals Advances in Breast MRI in the Setting of Ductal Carcinoma In Situ

2018 ◽  
Vol 53 (4) ◽  
pp. 261-269
Author(s):  
Nita Amornsiripanitch ◽  
Diana L. Lam ◽  
Habib Rahbar
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Mri

Solitary, Well-Circumscribed, T2 Hyperintense Masses on MRI Have Very Low Malignancy Rates

2019 ◽  
Vol 1 (1) ◽  
pp. 37-42 ◽  
Author(s):  
Lars J Grimm ◽  
Michael Enslow ◽  
Sujata V Ghate
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Mri ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Malignancy Rate ◽  
The Masses

Abstract Objective The purpose of this study was to determine the malignancy rate of solitary MRI masses with benign BI-RADS descriptors. Methods A retrospective review was conducted of all breast MRI reports that described a mass with a final BI-RADS assessment of 3, 4, or 5, from February 1, 2005, through February 28, 2014 (n = 1510). Studies were excluded if the mass was not solitary, did not meet formal criteria for a mass, or had classically suspicious BI-RADS features (e.g., washout kinetics, and spiculated margin). The masses were reviewed by 2 fellowship-trained breast radiologists who reported consensus BI-RADS mass margin, shape, internal-enhancement, and kinetics descriptors. The T2 signal was reported as hyperintense if equal to or greater than the signal intensity of the axillary lymph nodes. Pathology results or 2 years of imaging follow-up were recorded. Comparisons were made between mass descriptors and clinical outcomes. Results There were 127 women with 127 masses available for analysis. There were 76 (60%) masses that underwent biopsy for an overall malignancy rate of 4% (5/127): 2 ductal carcinoma in situ (DCIS) and 3 invasive ductal carcinoma. The malignancy rate was 2% (1/59) for T2 hyperintense solitary masses. The malignancy rate was greater than 2% for all of the following BI-RADS descriptors: oval (3%, 3/88), round (5%, 2/39), circumscribed (4%, 5/127), homogeneous (4%, 3/74), and dark internal septations (4%, 2/44). Conclusion T2 hyperintense solitary masses without associated suspicious features have a low malignancy rate, and they could be considered for a BI-RADS 3 final assessment.

scholarly journals Predictive factors for the presence of invasive components in patients diagnosed with ductal carcinoma in situ based on preoperative biopsy

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Kwan Ho Lee ◽  
Jeong Woo Han ◽  
Eun Young Kim ◽  
Ji Sup Yun ◽  
Yong Lai Park ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Preoperative Diagnosis ◽  
Ductal Carcinoma ◽  
Univariate Analysis ◽  
Breast Mri ◽  
Nuclear Grade ◽  
Preoperative Biopsy ◽  
Areolar Complex

Abstract Background In patients diagnosed with ductal carcinoma in situ (DCIS) with needle biopsy before surgery, invasive component (IC) is often found in the postoperative tissue, which results in altered post-surgical care. However, there are no clinically available factors to predict IC, and few MRI studies are available for the detection of IC in DCIS patients. The purpose of this study was to evaluate which risk factors can predict IC preoperatively. Methods Patients with a DCIS diagnosis based on preoperative biopsy, who underwent breast surgery Kangbuk Samsung Hospital between Jan 2005 and June 2018, were retrospectively evaluated. Clinico-pathological and breast MRI factors were compared between DCIS and DCIS with IC in postsurgical specimens. Results Of the 431 patients with a preoperative diagnosis of DCIS, 34 (7.9%) showed IC during the postoperative pathological investigations, and 217 (50.3%) underwent breast MRI. Among MRI-related factors, Mass-like enhancement on MRI was the sole but significant predictor of IC (HR = 0.26, C.I. = 0.07–0.93, p = 0.038), while nipple-areolar complex invasion, enhancement peak and pattern were not statistically significant. Nuclear grade was the only significant predictor of IC in the analysis of other clinico-pathological factors (HR = 2.39, C.I. = 1.05–5.42, p = 0.038 in univariate analysis, HR = 2.86, C.I. = 1.14–7.14, p = 0.025 in multivariate analysis). Conclusions Mass-like enhancement on MRI and high nuclear grade were associated with IC in patients with preoperative diagnosis of DCIS. Considering the high sensitivity of breast MRI for IC, further evaluation of the predictive value of MRI in preoperative DCIS patients is desirable.

Relationship of Breast Magnetic Resonance Imaging to Outcome After Breast-Conservation Treatment With Radiation for Women With Early-Stage Invasive Breast Carcinoma or Ductal Carcinoma in Situ

2008 ◽  
Vol 26 (3) ◽  
pp. 386-391 ◽  
Author(s):  
Lawrence J. Solin ◽  
Susan G. Orel ◽  
Wei-Ting Hwang ◽  
Eleanor E. Harris ◽  
Mitchell D. Schnall
Keyword(s):  
Breast Carcinoma ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Early Stage ◽  
Breast Mri ◽  
Invasive Breast Carcinoma ◽  
Breast Conservation Treatment ◽  
Mri Study

Purpose To determine the relationship of breast magnetic resonance imaging (MRI) to outcome after breast-conservation treatment (BCT) with radiation for women with early-stage invasive breast carcinoma or ductal carcinoma in situ. Patients and Methods A total of 756 women with early stage invasive breast carcinoma or ductal carcinoma in situ underwent BCT including definitive breast irradiation during 1992 to 2001. At the time of initial diagnosis and evaluation, routine breast imaging included conventional mammography. Of the 756 women, 215 women (28%) had also undergone a breast MRI study, and 541 women (72%) had not undergone a breast MRI study. The median follow-up after treatment was 4.6 years (range, 0.1 to 13.5 years). Results For the women with a breast MRI study compared with the women without a breast MRI study, there were no differences in the 8-year rates of any local failure (3% v 4%, respectively; P = .51) or local-only first failure (3% v 4%, respectively; P = .32). There were also no differences between the two groups for the 8-year rates of overall survival (86% v 87%, respectively; P = .51), cause-specific survival (94% v 95%, respectively; P = .63), freedom from distant metastases (89% v 92%, respectively; P = .16), or contralateral breast cancer (6% v 6%, respectively; P = .39). Conclusion The use of a breast MRI study at the time of initial diagnosis and evaluation was not associated with an improvement in outcome after BCT with radiation.

Symmetry-based detection of ductal carcinoma in situ in breast MRI

2012 ◽  
Vol 81 ◽  
pp. S158-S159
Author(s):  
Abhilash Srikantha ◽  
Markus Harz ◽  
Lei Wang ◽  
Bram Platel ◽  
Ritse M. Mann ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Mri

Preoperative Breast MRI in the Surgical Treatment of Ductal Carcinoma In Situ

2011 ◽  
Vol 18 (2) ◽  
pp. 151-156 ◽  
Author(s):  
Luisa C. Kropcho ◽  
Shawn T. Steen ◽  
Alice P. Chung ◽  
Myung-Shin Sim ◽  
Daniel L. Kirsch ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Mri ◽  
Preoperative Breast Mri

scholarly journals Revisit the practice of lymph node biopsy in patients diagnosed as ductal carcinoma in situ before operation: a retrospective analysis of 682 cases and evaluation of the role of breast MRI

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Hung-Wen Lai ◽  
Yi-Lin Chang ◽  
Shou-Tung Chen ◽  
Yu-Jun Chang ◽  
Wen-Pei Wu ◽  
...  
Keyword(s):  
Lymph Node ◽  
Ductal Carcinoma In Situ ◽  
Tumor Size ◽  
Predictive Value ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Mri ◽  
Invasive Cancer ◽  
Node Negative

Abstract Background The optimal axillary lymph node (ALN) management strategy in patients diagnosed with ductal carcinoma in situ (DCIS) preoperatively remains controversial. The value of breast magnetic resonance imaging (MRI) to predict ALN metastasis pre-operative DCIS patients was evaluated. Methods Patients with primary DCIS with or without pre-operative breast MRI evaluation and underwent breast surgery were recruited from single institution. The value of breast MRI for ALN evaluation, predictors of breast and ALN surgeries, upgrade from DCIS to invasive cancer, and ALN metastasis were analyzed. Results A total of 682 cases with pre-operative diagnosis of DCIS were enrolled in current study. The rate of upgrade to invasive cancer were found in 34.2% of specimen, and this upgrade rate is 23% for patients who received breast conserving surgery and 40.7% for mastectomy (p < 0.01). Large pre-operative imaging tumor size and post-operative invasive component were risk factors to ALN metastasis. Breast MRI had 53.8% sensitivity, 77.8% specificity, 14.9% positive predictive value, 95.9% negative predictive value (NPV), and 76.2% accuracy to predict ALN metastasis in pre-OP DCIS patients. In MRI node-negative breast cancer patients with MRI tumor size < 3 cm, the NPV was 96.4%, and all these false-negative cases were N1. Pre-OP diagnosed DCIS patients with MRI tumor size < 3 cm and node negative suitable for BCS could safely omit SLNB if whole breast radiotherapy is to be performed. Conclusion Breast MRI had high NPV to predict ALN metastasis in pre-OP DCIS patients, which is useful and could be provided as shared decision-making reference.

scholarly journals Preoperative breast MRI in management of patients with needle biopsy-proven ductal carcinoma in situ (DCIS)

2020 ◽  
Vol 46 (10) ◽  
pp. 1854-1860
Author(s):  
Sara van Bekkum ◽  
Bert P.M. ter Braak ◽  
Peter W. Plaisier ◽  
Joost van Rosmalen ◽  
Marian B.E. Menke-Pluijmers ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Needle Biopsy ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Mri ◽  
Preoperative Breast Mri

scholarly journals The Impact of Preoperative Breast MRI on Surgical Management of Women with Newly Diagnosed Ductal Carcinoma In Situ

2020 ◽  
Vol 27 (4) ◽  
pp. 478-486 ◽  
Author(s):  
Diana L. Lam ◽  
Jacob Smith ◽  
Savannah C. Partridge ◽  
Adrienne Kim ◽  
Sara H. Javid ◽  
...  
Keyword(s):  
Surgical Management ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Mri ◽  
Newly Diagnosed ◽  
Preoperative Breast Mri ◽  
The Impact
Sign in / Sign up

Export Citation Format

Share Document