Molecular evidence for the same clonal origin of both components of an adenosquamous Barrett carcinoma

2002 ◽  
Vol 122 (3) ◽  
pp. 784-788 ◽  
Author(s):  
Bastiaan P. van Rees ◽  
Remigio W. Rouse ◽  
Mireille J. de Wit ◽  
Carel J.M. van Noesel ◽  
Guido N.J. Tytgat ◽  
...  
Keyword(s):  
Molecular Evidence ◽  
Clonal Origin ◽  
Barrett Carcinoma

scholarly journals Epstein-Barr Virus–Negative Hodgkin's Lymphoma After Mycosis Fungoides: Molecular Evidence for Distinct Clonal Origin

2001 ◽  
Vol 14 (2) ◽  
pp. 91-97 ◽  
Author(s):  
Marcus Kremer ◽  
Michael Sandherr ◽  
Birgit Geist ◽  
Antonello D Cabras ◽  
Heinz Höfler ◽  
...  
Keyword(s):  
Mycosis Fungoides ◽  
Hodgkin’S Lymphoma ◽  
Epstein Barr Virus ◽  
Hodgkin's Lymphoma ◽  
Molecular Evidence ◽  
Barr Virus ◽  
Clonal Origin ◽  
Epstein Barr

CROCUS SATIVUS L. – MOLECULAR EVIDENCE ON ITS CLONAL ORIGIN

2010 ◽  
pp. 41-46 ◽  
Author(s):  
S. Fluch ◽  
K. Hohl ◽  
M. Stierschneider ◽  
D. Kopecky ◽  
B. Kaar
Keyword(s):  
Crocus Sativus ◽  
Molecular Evidence ◽  
Clonal Origin ◽  
Crocus Sativus L

scholarly journals Molecular Evidence for the Same Clonal Origin of Multifocal Papillary Thyroid Carcinomas

2006 ◽  
Vol 12 (8) ◽  
pp. 2414-2418 ◽  
Author(s):  
Ryan P. McCarthy ◽  
Mingsheng Wang ◽  
Timothy D. Jones ◽  
Randall W. Strate ◽  
Liang Cheng
Keyword(s):  
Molecular Evidence ◽  
Papillary Thyroid ◽  
Thyroid Carcinomas ◽  
Clonal Origin

scholarly journals Molecular evidence for the bi-clonal origin of neuroendocrine tumor derived metastases

BMC Genomics ◽  
2012 ◽  
Vol 13 (1) ◽  
pp. 594 ◽  
Author(s):  
Beate Rinner ◽  
Birgit Gallè ◽  
Slave Trajanoski ◽  
Carina Fischer ◽  
Martina Hatz ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Molecular Evidence ◽  
Clonal Origin

scholarly journals Molecular evidence for a single clonal origin in biphenotypic concomitant chronic lymphocytic leukemia and multiple myeloma

Blood ◽  
1989 ◽  
Vol 74 (6) ◽  
pp. 2062-2065 ◽  
Author(s):  
DL Saltman ◽  
JA Ross ◽  
RE Banks ◽  
FM Ross ◽  
AM Ford ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Chronic Lymphocytic Leukemia ◽  
B Cell ◽  
Lymphocytic Leukemia ◽  
Chain Gene ◽  
Molecular Evidence ◽  
Heavy Chain Gene ◽  
Lambda Light Chain ◽  
Clonal Origin ◽  
Cell Chronic Lymphocytic Leukemia

To establish the clonal origin of a case of concomitant B-cell chronic lymphocytic leukemia (IgM kappa) and multiple myeloma (IGA lambda), we analyzed the immunoglobulin (Ig) gene rearrangements in the patient's blood and bone marrow. Despite the different isotypes, pretreatment investigation of the heavy chain gene (JH) revealed a germline fragment and two identical rearrangements in the blood and marrow. Both kappa and lambda light-chain genes were rearranged in the blood, suggesting peripheral blood lymphocyte involvement in the myeloma. Analysis of the Ig genes after chemotherapy demonstrated no change in the JH or CK rearrangements; however, the lambda genes were now in a germline configuration. Our results suggest that in this patient both chronic lymphocytic leukemia and myeloma originated from the same B-cell progenitor.

scholarly journals Molecular evidence for a single clonal origin in biphenotypic concomitant chronic lymphocytic leukemia and multiple myeloma

Blood ◽  
1989 ◽  
Vol 74 (6) ◽  
pp. 2062-2065 ◽  
Author(s):  
DL Saltman ◽  
JA Ross ◽  
RE Banks ◽  
FM Ross ◽  
AM Ford ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Chronic Lymphocytic Leukemia ◽  
B Cell ◽  
Lymphocytic Leukemia ◽  
Chain Gene ◽  
Molecular Evidence ◽  
Heavy Chain Gene ◽  
Lambda Light Chain ◽  
Clonal Origin ◽  
Cell Chronic Lymphocytic Leukemia

Abstract To establish the clonal origin of a case of concomitant B-cell chronic lymphocytic leukemia (IgM kappa) and multiple myeloma (IGA lambda), we analyzed the immunoglobulin (Ig) gene rearrangements in the patient's blood and bone marrow. Despite the different isotypes, pretreatment investigation of the heavy chain gene (JH) revealed a germline fragment and two identical rearrangements in the blood and marrow. Both kappa and lambda light-chain genes were rearranged in the blood, suggesting peripheral blood lymphocyte involvement in the myeloma. Analysis of the Ig genes after chemotherapy demonstrated no change in the JH or CK rearrangements; however, the lambda genes were now in a germline configuration. Our results suggest that in this patient both chronic lymphocytic leukemia and myeloma originated from the same B-cell progenitor.

Direct molecular evidence for the expression of the 5-HT4 receptor in rat colonocytes

2001 ◽  
Vol 120 (5) ◽  
pp. A171-A171
Author(s):  
M STONER ◽  
D YAGER ◽  
J KELLUM
Keyword(s):  
Molecular Evidence
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