scholarly journals Adverse events with transvenous left ventricular pacing in patients with severe heart failure: early experience from a single centre

EP Europace ◽  
2001 ◽  
Vol 3 (1) ◽  
pp. 60-63 ◽  
Author(s):  
V Valls-Bertault
Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Stanley Tung ◽  
Kesava Rajagopalan ◽  
Andy Ignaszewski ◽  
Jonathan Affolter

Introduction: It is known that Cardiac Resynchronization Therapy (CRT) combining right ventricular (RV) apex pacing and left ventricular pacing (LVP) is ineffective in up to 35% of heart failure (HF) patients. Our hypothesis is that RV apical pacing bypasses the rapidly conducting right bundle and may further impede ventricular activation with LBBB hence a more physiological CRT is via HIS Bundle pacing (HBP) and LVP. We report of our early experience with Cardiac Electrical Resynchronization Therapy (CERT) incorporating HBP with LVP in patients with severe HF. Methods: Patients indicated for CRT were approached for CERT. In addition to an atrial and LV lead, patients also received a HBP lead. An active fixation lead (SelectSecure/Site® Medtronic) was used directly for HIS Bundle mapping and pacing. HBP implant thresholds, procedure and fluoroscopy times, pre and post implant QRS, PR interval, and NYHA class were collected. Student t -test was used for analysis. Results: 15 patients (13 male, mean age 70yrs) referred for CRT underwent successful CERT with mean follow up of 3.5±4.3 months. The mean implant HBP threshold, procedure and fluoroscopy time were 1.6V/0.6ms, 150min, and 26min respectively. All patients had QRS shortening with a mean of 64±21ms (pre CERT 182ms, post CERT 118ms, p<0.0001, figure ) and mean PR shortening of 81±101ms (pre CERT 254ms, post CERT 173ms, p<0.05). 13 patients had improvement of at least one NYHA class. Conclusions: HBP with LVP is effective in achieving electrical resynchronization, and has resulted in early improvement of HF symptoms. Evidence of reverse remodeling is pending. CERT needs to be further validated before considering for wide adoption.


EP Europace ◽  
2003 ◽  
Vol 4 (Supplement_2) ◽  
pp. B105-B105
Author(s):  
M. Heinke ◽  
H. Kuhnert ◽  
R. Surber ◽  
G. Dannberg ◽  
H.R. Figulla ◽  
...  

2011 ◽  
Vol 33 (1) ◽  
pp. 37-41
Author(s):  
Syed Y. Ahsan ◽  
Matthew W. Fittall ◽  
Aerakondal B. Gopalamurugan ◽  
James W. McCready ◽  
Laurence Nunn ◽  
...  

2010 ◽  
Vol 55 (6) ◽  
pp. 566-575 ◽  
Author(s):  
Nicolas Derval ◽  
Paul Steendijk ◽  
Lorne J. Gula ◽  
Antoine Deplagne ◽  
Julien Laborderie ◽  
...  

2000 ◽  
Vol 86 (11) ◽  
pp. 1267-1270 ◽  
Author(s):  
Gabriele Lupi ◽  
Michele Brignole ◽  
Daniele Oddone ◽  
Roberto Bollini ◽  
Carlo Menozzi ◽  
...  

2004 ◽  
Vol 15 (12) ◽  
pp. 1342-1347 ◽  
Author(s):  
PIERRE BORDACHAR ◽  
STEPHANE LAFITTE ◽  
SYLVAIN REUTER ◽  
STEPHANE GARRIGUE ◽  
PRASHANTHAN SANDERS ◽  
...  

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