scholarly journals Temporal and spatial dispersion of repolarization during premature impulse propagation in human intact ventricular muscle Comparison between single vs double premature stimulation

EP Europace ◽  
2000 ◽  
Vol 2 (3) ◽  
pp. 201-206 ◽  
Author(s):  
S Shimizu
Keyword(s):  
Spatial Dispersion ◽  
Ventricular Muscle ◽  
Dispersion Of Repolarization ◽  
Impulse Propagation ◽  
Temporal And Spatial

Interplay between temporal and spatial dispersion of repolarization in the initiation and perpetuation of Torsades de Pointes in the chronic AV-block dog

2021 ◽  
Author(s):  
Agnieszka Smoczynska ◽  
Errol W. Aarnink ◽  
Albert Dunnink ◽  
Alexandre Bossu ◽  
Valerie Y.H. van Weperen ◽  
...  
Keyword(s):  
Ventricular Arrhythmias ◽  
Spatial Dispersion ◽  
Three Dimensional ◽  
Torsades De Pointes ◽  
Av Block ◽  
Dispersion Of Repolarization ◽  
Ectopic Beats ◽  
The Mean ◽  
Temporal And Spatial ◽  
Temporal Dispersion

Ventricular arrhythmias, consisting of single ectopic beats (sEB), multiple EB (mEB), and Torsades de Pointes (TdP, defined as >5 beats with QRS vector twisting around isoelectric line) can be induced in the anesthetized chronic AV-block (CAVB) dog by dofetilide (IKr-blocker). The interplay between temporal dispersion of repolarization, quantified as short-term variability (STV), and spatial dispersion of repolarization (SDR) in the initiation and perpetuation of these arrhythmias remains unclear. Five inducible (>3 TdPs/10') CAVB dogs were observed for 10' from the start of dofetilide infusion (0.025mg/kg, 5'). An intracardiac decapolar electrogram (EGM) catheter and 30 intramural cardiac needles in the left ventricle (LV) were introduced. STVARI was derived from 31 consecutive activation recovery intervals (ARI) on the intracardiac EGM, using the formula: . The mean SDR3D in the LV was determined as the three-dimensional repolarization time differences between the intramural cardiac needles. Moments of measurement included baseline (BL) and after dofetilide infusion prior to first 1) sEB (occurrence at 100±35"), 2) mEB (224±96"), and 3) non self-terminating TdP (454±298"). STVARI increased from 2.15±0.32ms at BL to 3.73±0.99ms* prior to the first sEB and remained increased without further significant progression to mEB (4.41±0.45ms*) and TdP (5.07±0.84ms*) (*p<0.05 compared to BL). SDR3D did not change from 31±11ms at BL to 43±13ms prior to sEB, but increased significantly prior to mEB (68±7ms*) and to TdP (86±9ms*+) (+p<0.05 compared to sEB). An increase in STV contributes to the initiation of sEB whereas an increase in SDR is important for the perpetuation of non self-terminating TdPs.

E-Collaboration Media Use and Diversity Perceptions

2012 ◽  
Vol 8 (2) ◽  
pp. 28-46 ◽  
Author(s):  
Sherry M. B. Thatcher ◽  
Susan A. Brown ◽  
Jeffrey L. Jenkins
Keyword(s):  
Life Cycle ◽  
Spatial Dispersion ◽  
Media Use ◽  
Virtual Organization ◽  
Theoretical Framework ◽  
Virtual Organizations ◽  
Organizational Evolution ◽  
Media Synchronicity ◽  
Temporal And Spatial ◽  
Media Characteristics

Virtual organizations enable collaboration and interaction among a diverse set of people regardless of their temporal and spatial dispersion. Throughout the life of a virtual organization, diversity plays an influential role in determining outcomes that ultimately affect the longevity and success of the organization. The goal of this paper is to describe the role diversity plays during different organizational evolutionary approaches, and how e-collaboration media characteristics interact with diversity and organizational evolution to influence outcomes. The authors leverage media synchronicity theory to discuss how the characteristics of different e-collaboration media can reduce or enhance perceived diversity. The role that perceived diversity has in determining outcomes is a function of whether a virtual organization is evolving according to the life-cycle, telelogical, or dialectic evolutionary approaches. Guided by organizational evolution, diversity, attribution, and media theories, the authors propose a theoretical framework with a set of propositions. The authors also provide an illustration of how the framework may be implemented by managers of virtual organizations.

Increased Temporo-Spatial Dispersion of Repolarization During Double Premature Stimulation in the Intact Ventricle

1992 ◽  
Vol 15 (11) ◽  
pp. 2194-2199 ◽  
Author(s):  
YOSHINORI KOBAYASHI ◽  
MASAMICHI GOTOH ◽  
W.J. MANDEL ◽  
HRAYR S. KARAGUEUZIAN
Keyword(s):  
Spatial Dispersion ◽  
Dispersion Of Repolarization

scholarly journals Increased temporal and spatial dispersion of reporalization during premature impulse propagatiom. Comparison between single and dowble premature stimuli.

1999 ◽  
Vol 19 (4) ◽  
pp. 351-361
Author(s):  
Shuichi Shimizu ◽  
Yoshinori Kobayashi ◽  
Yasushi Miyauchi ◽  
Naomi Kawaguchi ◽  
Hirokazu Saitoh ◽  
...  
Keyword(s):  
Spatial Dispersion ◽  
Temporal And Spatial
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