scholarly journals Use of fluorquinolones is associated with a reduced risk of coronary heart disease in diabetes mellitus type 2 patients

2002 ◽  
Vol 23 (20) ◽  
pp. 1575-1579 ◽  
Author(s):  
J Erkens
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Mellitus Type ◽  
Reduced Risk

scholarly journals Differences Characteristics Patients Diabetes Mellitus Type 2 with and without Coronary Heart Disease

2017 ◽  
Vol 5 (1) ◽  
pp. 37
Author(s):  
Nindara Citra Aquarista
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
General Hospital ◽  
Diabetes Mellitus Type 2 ◽  
Smoking Habit ◽  
Smoking Behavior ◽  
Diabetes Mellitus Type ◽  
Significant Difference

Diabetes mellitus is the third highest Non-Communicable Diseases (NCDs), which causes death in Indonesia.The incidence of coronary heart disease in diabetes mellitus is high, 65% of people with diabetes mellitus die due to coronary heart disease and stroke. The purpose of this study is to analyze the differences in the characteristics of Diabetes mellitus type 2 in patients with and without coronary heart disease in Haji General Hospital Surabaya year 2016. This research uses observational analysis with cross sectional study design. The subject of the study is the incidence of diabetes Mellitus type 2 with and without coronary heart disease with undergoing outpatient treatment at Haji General Hospital Surabaya year 2016. The Samples were taken by fixed-disease sampling method with 42 people as the samples. The data analysis uses Chi Square test. The results show for the independent variables that have the most significant difference inHaji General Hospital Surabaya year 2016 is smoking behavior (p = 0.00; PR = 7.85; 95% CI = 2.09 to 29.50) and hypertension (p = 0,002; PR = 3.51; 95% CI = 1.42 to 8.67). In conclusion, the smoking behavior and hypertension can lead to complications of coronary heart disease for patients with type in Diabetes Mellitus type 2 in Haji General Hospital year 2016. It needs awareness to check blood pressure regularly and eliminate the smoking habit as the prevention of complications of coronary heart disease for patients with diabetes mellitus type 2.Keywords: diabetes mellitus type 2, coronary hearth disease.

scholarly journals Cost-effectiveness of a stepped care program to prevent depression among primary care patients with diabetes mellitus type 2 and/or coronary heart disease and subthreshold depression in comparison with usual care

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
S. E. M. van Dijk ◽  
A. D. Pols ◽  
M. C. Adriaanse ◽  
H. W. J. van Marwijk ◽  
M. W. van Tulder ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cost Effectiveness ◽  
Major Depression ◽  
Usual Care ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Mellitus Type ◽  
Subthreshold Depression

Abstract Background Patients with diabetes mellitus type 2 (DM2) and/or coronary heart disease (CHD) are at high risk to develop major depression. Preventing incident major depression may be an important tool in reducing the personal and societal burden of depression. The aim of the current study was to assess the cost-effectiveness of a stepped care program to prevent major depression (Step-Dep) in diabetes mellitus type 2 and/or coronary heart disease patients with subthreshold depression in comparison with usual care. Methods An economic evaluation with 12 months follow-up was conducted alongside a pragmatic cluster-randomized controlled trial from a societal perspective. Participants received care as usual (n = 140) or Step-Dep (n = 96) which consisted of four sequential treatment steps: watchful waiting, guided self-help, problem solving treatment and referral to a general practitioner. Primary outcomes were quality-adjusted life years (QALYs) and cumulative incidence of major depression. Costs were measured every 3 months. Missing data was imputed using multiple imputation. Uncertainty around cost-effectiveness outcomes was estimated using bootstrapping and presented in cost-effectiveness planes and acceptability curves. Results There were no significant differences in QALYs or depression incidence between treatment groups. Secondary care costs (mean difference €1644, 95% CI €344; €3370) and informal care costs (mean difference €1930, 95% CI €528; €4089) were significantly higher in the Step-Dep group than in the usual care group. The difference in total societal costs (€1001, 95% CI €-3975; €6409) was not statistically significant. The probability of the Step-Dep intervention being cost-effective was low, with a maximum of 0.41 at a ceiling ratio of €30,000 per QALY gained and 0.32 at a ceiling ratio of €0 per prevented case of major depression. Conclusions The Step-Dep intervention is not cost-effective compared to usual care in a population of patients with DM2/CHD and subthreshold depression. Therefore, widespread implementation cannot be recommended. Trial registration The trial was registered in the Netherlands Trial Register (NTR3715).

scholarly journals Differences Characteristics Patients Diabetes Mellitus Type 2 with and without Coronary Heart Disease

2017 ◽  
Vol 5 (1) ◽  
pp. 37
Author(s):  
Nindara Citra Aquarista
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
General Hospital ◽  
Diabetes Mellitus Type 2 ◽  
Smoking Habit ◽  
Smoking Behavior ◽  
Diabetes Mellitus Type ◽  
Significant Difference

Diabetes mellitus is the third highest Non-Communicable Diseases (NCDs), which causes death in Indonesia. The incidence of coronary heart disease in diabetes mellitus is high, 65% of people with diabetes mellitus die due to coronary heart disease and stroke. The purpose of this study is to analyze the differences in the characteristics of Diabetes mellitus type 2 in patients with and without coronary heart disease in Haji General Hospital Surabaya year 2016. This research uses observational analysis with cross sectional study design.The subject of the study is the incidence of diabetes Mellitus type 2 with and without coronary heart disease with undergoing outpatient treatment at Haji General Hospital Surabaya year 2016. The Samples were taken by fixed-disease sampling method with 42 people as the samples. The data analysis uses Chi Square test. The results show for the independent variables that have the most significant difference inHaji General Hospital Surabaya year 2016 is smoking behavior (p = 0.00; PR = 7.85; 95% CI = 2.09 to 29.50) and hypertension (p= 0,002; PR = 3.51; 95% CI = 1.42 to 8.67). In conclusion, the smoking behavior and hypertension can lead to complications of coronary heart disease for patients with type in Diabetes Mellitus type 2 in Haji General Hospital year 2016. It needs awareness to check blood pressure regularly and eliminate the smoking habit as the prevention of complications of coronary heart disease for patients with diabetes mellitus type 2.Keywords: diabetes mellitus type 2, coronary hearth disease.

Lipid peroxidation and antioxidant system in patients with acute мyocardial infarction and diabetes mellitus type 2

2015 ◽  
Vol 9 (4) ◽  
pp. 0-0
Author(s):  
Загородняя ◽  
T. Zagorodnyaya ◽  
Корниенко ◽  
E. Kornienko ◽  
Иванов ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Myocardial Infarction ◽  
Lipid Peroxidation ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Antioxidant System ◽  
Diabetes Mellitus Type 2 ◽  
Coronary Intervention ◽  
Diabetes Mellitus Type

Problems of the treatment of comorbid patients in routine clinical practice remain highly relevant. One of the most common combinations – coronary heart disease and diabetes mellitus type 2. In this article, the authors present their own experience of studying the effects of infusion of the drug "Reamberin" at the stage of percutaneous coronary intervention on the dynamics of indicators of lipid peroxidation in patients with myocardial infarction with diabetes mellitus type 2. This study consists of the examination and treatment analysis of 54 patients, men aged 64,3 ± 6,8 years old with coronary heart disease and clinical manifestations of acute myocardial infarction and concomitant diabetes mellitus type 2. The percutaneous intervention was made of this group of patients. To determine the normal values of the studied parameters, the examination of 34 patients with coronary heart disease without exacerbation (men aged 62,5 ± 4,2 years) with concomitant diabetes mellitus type 2, was carried out. It is found that the development of acute myocardial infarction in patients with diabetes type 2 is accompanied by activation of processes of lipid peroxidation and antioxidant system of blood with a predominance of lipid peroxidation. It is proved that the use of succinic acid drug "Reamberin" at the stage of percutaneous coronary intervention in these patients contributes to the decrease in the intensity of free radical processes and increases the activity of enzymatic antioxidants.

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