Pathogenesis, risk factors, and incidence of upper gastrointestinal bleeding after cardiac surgery: Is specific prophylaxis in routine bypass procedures needed?

2000 ◽  
Vol 14 (3) ◽  
pp. 293-299 ◽  
Author(s):  
Peter H.J. van der Voort ◽  
Durk F. Zandstra
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Upper Gastrointestinal

scholarly journals Upper gastrointestinal bleeding after open heart surgery

2014 ◽  
Vol 05 (03) ◽  
pp. 101-105
Author(s):  
Aithoussa Mahdi ◽  
Atmani Noureddine ◽  
Moutakiallah Younes ◽  
Bamous Mehdi ◽  
Abdou Abdessamad ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Gastrointestinal Bleeding ◽  
Heart Surgery ◽  
Upper Gastrointestinal Bleeding ◽  
Prolonged Mechanical Ventilation ◽  
Open Heart Surgery ◽  
Lactate Concentration ◽  
Independent Risk Factors ◽  
Upper Gastrointestinal

Abstract Objective: The occurrence of digestive complications especially upper gastrointestinal bleeding (UGIB) has increased after cardiac surgery. The aim of this study was to determine the incidence of UGIB and identify the independent risk factors. Materials and Methods: We retrospectively analyzed data of 1077 patients undergoing cardiopulmonary bypass (CPB) from 1994 to 2012 The group of patients with UGIB (n 1 = 20) was compared with the population group (n 2 = 1057). Demographic characteristics, therapeutic management, endoscopic findings, and outcomes were analyzed. Through a regression analysis we identified independent risk factors of UGIB. Results: The mean age of the group n 1 was 58.2 ± 12.4 years and 50.18 ± 13.5 years in the group n 2. UGIB occurred about 13 ± 5.5 days after cardiac surgery. Gastroduodenal ulcer was the most common etiology of hemorrhage (n = 13, 65%). Renal insufficiency, previous gastric ulcer, increased lactate concentration during CPB, prolonged mechanical ventilation, use of vasopressor drug and pulmonary infection was likely contributing factors in UGIB. Conclusion: UGIB following open cardiac surgery is most frequently secondary to gastroduodenal ulceration. Many determinant factors of bleeding are incriminated. Surgeons must be aware of these factors to avoid fatal complications.

scholarly journals Risk factors for upper gastrointestinal bleeding among end-stage renal disease patients

2003 ◽  
Vol 64 (4) ◽  
pp. 1455-1461 ◽  
Author(s):  
Haimanot Wasse ◽  
Daniel L. Gillen ◽  
Adrianne M. Ball ◽  
Bryan R. Kestenbaum ◽  
Stephen L. Seliger ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastrointestinal Bleeding ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Upper Gastrointestinal Bleeding ◽  
Stage Renal Disease ◽  
End Stage ◽  
Upper Gastrointestinal

Risk factors for upper gastrointestinal bleeding in intensive care unit patients

1996 ◽  
Vol 24 (12) ◽  
pp. 1974-1981 ◽  
Author(s):  
Richard T. Ellison ◽  
Guillermo Perez-Perez ◽  
Carolyn H. Welsh ◽  
Martin J. Blaser ◽  
Katherine A. Riester ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Upper Gastrointestinal

INFLUENCE OF RISK FACTORS ON DEVELOPMENT OF STRESS RELATED UPPER GASTROINTESTINAL BLEEDING (SR-UGIB)

1993 ◽  
Vol 21 (Supplement) ◽  
pp. S253
Author(s):  
Craig Metz ◽  
Gerald Larson ◽  
David Livingston ◽  
J. Stanley Smith
Keyword(s):  
Risk Factors ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Upper Gastrointestinal

scholarly journals Risk Factors for Upper Gastrointestinal Bleeding in Patients Taking Selective COX-2 Inhibitors: A Nationwide Population-Based Cohort Study

Pain Medicine ◽  
2017 ◽  
Vol 19 (2) ◽  
pp. 225-231 ◽  
Author(s):  
Xi-Hsuan Lin ◽  
Shih-Hao Young ◽  
Jiing-Chyuan Luo ◽  
Yen-Ling Peng ◽  
Ping-Hsien Chen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Population Based ◽  
Cox 2 ◽  
Cox 2 Inhibitors ◽  
Upper Gastrointestinal

scholarly journals In-Hospital Nonvariceal Upper Gastrointestinal Bleeding following Cardiac Surgery: Patient Characteristics, Endoscopic Lesions and Prognosis

Ulcers ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Marcos Amorim ◽  
Alan N. Barkun ◽  
Martin Larocque ◽  
Karl Herba ◽  
Benoit DeVarennes ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Cardiac Surgery ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Patient Characteristics ◽  
Hemodynamic Instability ◽  
Predictors Of Outcome ◽  
Surgery Patient ◽  
Endoscopic Characteristics ◽  
Upper Gastrointestinal

Background. Nonvariceal upper gastrointestinal bleeding (NVUGIB) can occur following cardiac surgery, with sparse contemporary data on patient characteristics and predictors of outcome in this setting. Aim. To describe the clinical and endoscopic characteristics of patients with NVUGIB following cardiac surgery and characterize predictors of outcome. Methods. Retrospective review of 131 consecutive patients with NVUGIB following cardiac surgery from 2002 to 2005. Demographic characteristics, therapeutic management, and predictors of outcomes were determined. Results. 69.5% were male, mean age: 68.8 ± 10.2 yrs, mean Parsonnet score: 24.6 ± 14.2. Commonest symptoms included melena (59.4%) or coffee ground emesis (25.8%). In-hospital medications included ASA (88.5%), heparin (95.4%, low molecular weight 6.9%), coumadin (48.1%), clopidogrel (22.9%), and NSAIDS (42%). Initial hemodynamic instability was noted in 47.1%. Associated laboratory results included hematocrit 26 ± 6, platelets 243 ± 133 109/L, INR 1.7 ± 1.6, and PTT 53.3 ± 35.6 s. Endoscopic evaluation (122 patients) yielded ulcers (85.5%) with high-risk lesions in 45.5%. Ulcers were located principally in the stomach (22.5%) or duodenum (45.9%). Many patients had more than one lesion, including esophagitis (28.7%) or erosions (26.8%). 48.8% received endoscopic therapy. Mean lengths of intensive care unit and overall stays were 10.4 ± 18.4 and 39.4 ± 46.9 days, respectively. Overall mortality was 19.1%. Only mechanical ventilation under 48 hours predicted mortality (O.R = 0.11; 95% CI = 0.04−0.34). Conclusions. This contemporary cohort of consecutive patients with NVUGIB following cardiac surgery bled most often from ulcers or esophagitis; many had multiple lesions. ICU and total hospital stays as well as mortality were significant. Mechanical ventilation for under 48 hours was associated with improved survival.

Sign in / Sign up

Export Citation Format

Share Document