Myosin heavy chain isoform and ubiquitin protease mRNA expression after passive leg cycling in persons with spinal cord injury

2000 ◽  
Vol 81 (2) ◽  
pp. 157-163
Author(s):  
Darryn S. Willoughby ◽  
Joe W. Priest ◽  
Russell A. Jennings
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Mrna Expression ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Myosin Heavy Chain Isoform ◽  
Cord Injury ◽  
Leg Cycling

Changes in detrusor smooth muscle myosin heavy chain mRNA expression following spinal cord injury in the mouse

2005 ◽  
Vol 24 (1) ◽  
pp. 89-95 ◽  
Author(s):  
Tracey S. Wilson ◽  
Khaled Abdel Aziz ◽  
Dolores Vazques ◽  
Lisa-Ann Wuermser ◽  
Victor K. Lin ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Smooth Muscle ◽  
Mrna Expression ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Smooth Muscle Myosin ◽  
Detrusor Smooth Muscle ◽  
Cord Injury ◽  
Muscle Myosin

Changes In Soleus Myosin Heavy Chain Expression In Response To Training Following Spinal Cord Injury

2005 ◽  
Vol 37 (Supplement) ◽  
pp. S34-S35
Author(s):  
Min Liu ◽  
Prodip Bose ◽  
Floyd Thompson ◽  
Glenn Walter ◽  
Douglas Anderson ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Cord Injury

scholarly journals Changes In Soleus Myosin Heavy Chain Expression In Response To Training Following Spinal Cord Injury

2005 ◽  
Vol 37 (Supplement) ◽  
pp. S34???S35
Author(s):  
Min Liu ◽  
Prodip Bose ◽  
Floyd Thompson ◽  
Glenn Walter ◽  
Douglas Anderson ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Cord Injury

scholarly journals Effect of cervicolumbar coupling on spinal reflexes during cycling after incomplete spinal cord injury

2018 ◽  
Vol 120 (6) ◽  
pp. 3172-3186 ◽  
Author(s):  
R. Zhou ◽  
B. Parhizi ◽  
J. Assh ◽  
L. Alvarado ◽  
R. Ogilvie ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
H Reflex ◽  
Spinal Reflexes ◽  
Incomplete Spinal Cord Injury ◽  
Reflex Amplitude ◽  
Arm Cycling ◽  
Cord Injury ◽  
Leg Cycling ◽  
Cycling Training

Spinal networks in the cervical and lumbar cord are actively coupled during locomotion to coordinate arm and leg activity. The goals of this project were to investigate the intersegmental cervicolumbar connectivity during cycling after incomplete spinal cord injury (iSCI) and to assess the effect of rehabilitation training on improving reflex modulation mediated by cervicolumbar pathways. Two studies were conducted. In the first, 22 neurologically intact (NI) people and 10 people with chronic iSCI were recruited. The change in H-reflex amplitude in flexor carpi radialis (FCR) during leg cycling and H-reflex amplitude in soleus (SOL) during arm cycling were investigated. In the second study, two groups of participants with chronic iSCI underwent 12 wk of cycling training: one performed combined arm and leg cycling (A&L) and the other legs only cycling (Leg). The effect of training paradigm on the amplitude of the SOL H-reflex was assessed. Significant reduction in the amplitude of both FCR and SOL H-reflexes during dynamic cycling of the opposite limbs was found in NI participants but not in participants with iSCI. Nonetheless, there was a significant reduction in the SOL H-reflex during dynamic arm cycling in iSCI participants after training. Substantial improvements in SOL H-reflex properties were found in the A&L group after training. The results demonstrate that cervicolumbar modulation during rhythmic movements is disrupted in people with chronic iSCI; however, this modulation is restored after cycling training. Furthermore, involvement of the arms simultaneously with the legs during training may better regulate the leg spinal reflexes.NEW & NOTEWORTHY This work systematically demonstrates the disruptive effect of incomplete spinal cord injury on cervicolumbar coupling during rhythmic locomotor movements. It also shows that the impaired cervicolumbar coupling could be significantly restored after cycling training. Actively engaging the arms in rehabilitation paradigms for the improvement of walking substantially regulates the excitability of the lumbar spinal networks. The resulting regulation may be better than that obtained by interventions that focus on training of the legs only.

Leg Cycling Dynamics Of Individuals With Spinal Cord Injury During Stationary Leg Cycle Ergometry

2005 ◽  
Vol 37 (Supplement) ◽  
pp. S120
Author(s):  
Randy D. Trumbower ◽  
Pouran D. Faghri ◽  
Sanguthevar Rajasekaran
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cycle Ergometry ◽  
Cord Injury ◽  
Leg Cycle Ergometry ◽  
Leg Cycling
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