Intravenous and subcutaneous weight-based dosing of the low molecular weight heparin tinzaparin (Innohep) in end-stage renal disease patients undergoing chronic hemodialysis

2002 ◽  
Vol 40 (3) ◽  
pp. 531-538 ◽  
Author(s):  
James W. Hainer ◽  
Donald J. Sherrard ◽  
Suzanne K. Swan ◽  
Jeffrey S. Barrett ◽  
Christopher A. Assaid ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Low Molecular Weight Heparin ◽  
Chronic Hemodialysis ◽  
Low Molecular Weight ◽  
Stage Renal Disease ◽  
End Stage

Low-Molecular Weight Proteins in End-Stage Renal Disease: Potential Toxicity and Dialytic Removal Mechanisms

2002 ◽  
Vol 13 (suppl 1) ◽  
pp. S41-S47
Author(s):  
William R. Clark ◽  
Dayong Gao
Keyword(s):  
Molecular Weight ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Low Molecular Weight ◽  
Renal Metabolism ◽  
Susceptibility To Infection ◽  
Removal Mechanisms ◽  
Stage Renal Disease ◽  
End Stage ◽  
Low Molecular Weight Proteins

ABSTRACT. Low-molecular-weight proteins (LMWP) are now recognized as a distinct class of uremic toxins, and numerous compounds in this category have been identified. Dr. Henderson has spent much of his career investigating ways to enhance the removal of intermediate- and large-sized uremic retention molecules. As LMWP clearly fall under this category, it is fitting to provide a review of several aspects of this molecular class. Normal renal metabolism of LMWP is discussed along with the changes that occur during chronic renal insufficiency. The effect of end-stage renal disease on plasma LMWP concentrations is assessed. As examples of the potential uremic toxicity of this molecular class, leptin, adrenomedullin, and the compounds associated with increased susceptibility to infection are highlighted. Finally, an overview of LMWP removal mechanisms for both hemodialysis and the convective therapies is provided.

Relationship Between Volume Status and Blood Pressure in Children with End Stage Renal Disease on Chronic Hemodialysis

2007 ◽  
Vol 7 (2) ◽  
pp. 210-215
Author(s):  
Fatina I. Fadel ◽  
Samar M. Sabry ◽  
Azza M.O. Abdel Rahm ◽  
Emad Eldin E. Salama ◽  
Marwa M. El-Sonbaty
Keyword(s):  
Blood Pressure ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Chronic Hemodialysis ◽  
Volume Status ◽  
Stage Renal Disease ◽  
End Stage
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