History of myocardial infarction and stroke among incident end-stage renal disease cases and population-based controls: An analysis of shared risk factors

2002 ◽  
Vol 40 (2) ◽  
pp. 323-330 ◽  
Author(s):  
Paul Muntner ◽  
Josef Coresh ◽  
Michael J. Klag ◽  
Paul K. Whelton ◽  
Thomas V. Perneger
2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Eun Lee ◽  
Ju Hee Han ◽  
Chul Hwan Bang ◽  
Seung Ah Yoo ◽  
Kyung Do Han ◽  
...  

Abstract Psoriasis is a chronic inflammatory skin disorder mediated by the T-cell–related immune response. Psoriatic patients may have a variety of comorbidities, but their risk of end-stage renal disease (ESRD), particularly according to the subtype of psoriasis, is unclear. We investigated the risk of ESRD in patients with psoriasis according to the subtype of psoriasis and history of systemic therapy for psoriasis. A total of 2,121,228 adults (1,590,921 in the control group and 530,307 in the psoriasis group) were enrolled in this nationwide population-based cohort study until 2015. During follow-up, 1,434 of the subjects in the psoriasis group developed ESRD. After adjusting for confounding factors, psoriasis was associated with the risk of ESRD (hazard ratio (HR) 1.58, 95% confidence interval [95% CI] 1.47–1.68). The psoriatic arthritis group (HR 7.60, 95% CI 1.90–30.41) had a higher risk of ESRD than the control group. Interestingly, no such association was detected in the systemically treated group (HR 1.07, 95% CI 0.80–1.41). Moreover, the acitretin-treated group had a lower risk of ESRD (HR 0.658, 95% CI, 0.494–0.875) than the non-systemically treated group. In conclusion, the risk of developing ESRD in patients with psoriasis differed according to the type of treatment and the presence of arthritis.


2018 ◽  
Vol 50 (11-12) ◽  
pp. 831-836 ◽  
Author(s):  
Gabrielle Dagasso ◽  
Joslyn Conley ◽  
Elizabeth Parfitt ◽  
Kelsey Pasquill ◽  
Lisa Steele ◽  
...  

2005 ◽  
Vol 25 (6) ◽  
pp. 529-535 ◽  
Author(s):  
Barry I. Freedman ◽  
Nataliya V. Volkova ◽  
Scott G. Satko ◽  
Jenna Krisher ◽  
Claudine Jurkovitz ◽  
...  

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Michelle R. Kaminski ◽  
Katrina A. Lambert ◽  
Anita Raspovic ◽  
Lawrence P. McMahon ◽  
Bircan Erbas ◽  
...  

Abstract Background Dialysis patients experience high rates of foot ulceration. Although risk factors for ulceration have been extensively studied in patients with diabetes, there is limited high-quality, longitudinal evidence in the dialysis population. Therefore, this study investigated risk factors for foot ulceration in a stable dialysis cohort. Methods We prospectively collected clinical, demographic, health status, and foot examination information on 450 adults with end-stage renal disease from satellite and home-therapy dialysis units in Melbourne, Australia over 12 months. The primary outcome was foot ulceration. Cox proportional hazard modelling and multinomial regression were used to investigate risk factors. Results Among 450 dialysis patients (mean age, 67.5 years; 64.7% male; 94% hemodialysis; 50.2% diabetes), new cases of foot ulceration were identified in 81 (18%) participants. Overall, risk factors for foot ulceration were neuropathy (HR 3.02; 95% CI 1.48 to 6.15) and previous ulceration (HR 2.86; CI 1.53 to 5.34). In those without history of ulceration, nail pathology (RR 3.85; CI 1.08 to 13.75) and neuropathy (RR 2.66; CI 1.04 to 6.82) were risk factors. In those with history of ulceration, neuropathy (RR 11.23; CI 3.16 to 39.87), peripheral arterial disease (RR 7.15; CI 2.24 to 22.82) and cerebrovascular disease (RR 2.08; CI 1.04 to 4.16) were risk factors. There were 12 (2.7%) new amputations, 96 (21.3%) infections, 24 (5.3%) revascularizations, 42 (9.3%) foot-related hospitalizations, and 52 (11.6%) deaths. Conclusions Neuropathy and previous ulceration are major risk factors for foot ulceration in dialysis patients. Risk factors differ between those with and without prior ulceration. The risk factors identified will help to reduce the incidence of ulceration and its associated complications.


2014 ◽  
Vol 60 (4) ◽  
pp. 627-638 ◽  
Author(s):  
Keri N. Althoff ◽  
Kathleen A. McGinnis ◽  
Christina M. Wyatt ◽  
Matthew S. Freiberg ◽  
Cynthia Gilbert ◽  
...  

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