scholarly journals Factors influencing the recurrence of keratocysts: monocentric study

2019 ◽  
Vol 26 (1) ◽  
pp. 1
Author(s):  
Francesco Giovacchini ◽  
Caterina Bensi ◽  
Daniele Paradiso ◽  
Stefano Belli ◽  
Valeria Mitro ◽  
...  
Keyword(s):  
Recurrence Rate ◽  
Medical Records ◽  
Odontogenic Keratocyst ◽  
High Tendency ◽  
Carnoy’S Solution ◽  
Factors Influencing ◽  
Odontogenic Keratocysts ◽  
Soft Tissue Involvement ◽  
Simple Enucleation ◽  
Aggressive Clinical Behavior

Introduction: The purpose of the study was to retrospectively analyse the recurrence rate of odontogenic keratocysts and to identify eventual features of the lesions that may influence recurrence. Material and methods: This was a retrospective study carried out for a period of 3 years. The medical records of patients treated in our institution were analysed to identify all the cases of odontogenic keratocysts. Results: A total of 16 odontogenic keratocysts were recorded. These lesions were treated with simple enucleation with or without adjuvant Carnoy's solution. The relapse occurred in 4 patients treated with simple enucleation and in none of the patients that underwent enucleation and Carnoy's solution application. The kind of treatment appeared not to influence recurrence rate at statistical analysis. Conclusions: Odontogenic keratocyst is a lesion with a locally aggressive behavior and a high tendency to relapse. This tendency of recurrence may be greater with syndromic presentation of odontogenic keratocyst, with soft tissue involvement, and with teeth proximity to the lesion. The application of Carnoy's solution may be useful to minimize recurrence rate in those odontogenic keratocysts with an aggressive clinical behavior and secondly may be used for all the other lesions treated with simple enucleation that experienced relapse.

A Review of the Odontogenic Keratocyst and Report of a Case

2019 ◽  
pp. 1-7
Author(s):  
M. Chandra Sekhar ◽  
D. Ayesha Thabusum ◽  
M. Charitha ◽  
G. Chandrasekhar ◽  
M. Shalini
Keyword(s):  
Recurrence Rate ◽  
Cystic Lesion ◽  
Soft Tissues ◽  
Clinical History ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Clinical Behavior ◽  
Clinical Appearance ◽  
Odontogenic Origin ◽  
Aggressive Clinical Behavior

The Odontogenic keratocyst (OKC) is a developmental, non – inflammatory chronic cystic lesion, on radiograph it may be unilocular or multi locular OKC is a cyst of odontogenic origin, usually asymptomatic with an aggressive clinical behavior including a high recurrence rate and tendency to invade bone and adjacent soft tissues. Diagnosis is based on the clinical history, clinical appearance, and radiographs and histology. A case of odontogenic keratocyst involving the ramus of the mandible is presented in this article emphasizing on the characteristics and various features of OKC.

Odontogenic Keratocyst: Diagnosis and Treatment

1983 ◽  
Vol 91 (2) ◽  
pp. 167-172 ◽  
Author(s):  
Stephen J. Wetmore ◽  
James D. Billie ◽  
Arthur Howe ◽  
William Wetzel
Keyword(s):  
Recurrence Rate ◽  
Surgical Therapy ◽  
Basal Cell ◽  
Squamous Epithelium ◽  
Diagnosis And Treatment ◽  
Odontogenic Keratocyst ◽  
Basal Cell Nevus Syndrome ◽  
Odontogenic Keratocysts

The odontogenic keratocyst is a keratinizing squamous epithelium-lined cyst that occurs in the mandible and maxilla. In 5% to 10% of patients the keratocysts may be a manifestation of the basal cell nevus syndrome. The recurrence rate after surgical therapy for odontogenic keratocysts varies from 10% to 63%.

scholarly journals 14-Year evolution odontogenic keratocyst: Case report

2021 ◽  
Vol 62 (1) ◽  
Author(s):  
Cintia Milani ◽  
◽  
Camyla Mauricio ◽  
Luciano Francio ◽  
Natanael Mattos ◽  
...  
Keyword(s):  
Case Report ◽  
Recurrence Rate ◽  
Bone Destruction ◽  
Good Alternative ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Standard Protocol ◽  
Recurrence Rates ◽  
Panoramic Radiographs ◽  
Carnoy’S Solution

Odontogenic keratocyst is a developmental odontogenic cyst that is usually diagnosed in routine radiographs in the early stages. This fact increases the dentist’s responsibility for its diagnosis, and the professional should pay attention to all maxillomandibular complex and not only to the teeth. There is no standard protocol for the treatment of odontogenic keratocyst. However, surgical resection is recommended because of its high recurrence rate, especially in those cases with extensive bone destruction. The enucleation followed by Carnoy’s solution application has been shown to be a good alternative to resection and pointed out as the conservative method associated with the lowest recurrence rates in the treatment of odontogenic keratocyst. This study aimed to report a case of an extensive odontogenic keratocyst with more than 14 years of evolution that had not been diagnosed in three previous different panoramic radiographs and was treated with enucleation and application of Carnoy’s solution.

scholarly journals A clinicopathological study and management of odontogenic keratocyst

2019 ◽  
Vol 9 (1) ◽  
pp. 8-15
Author(s):  
Mohammad Asifur Rahman ◽  
Tarin Rahman ◽  
Ismat Ara Haider
Keyword(s):  
Conservative Treatment ◽  
Recurrence Rate ◽  
Surgical Resection ◽  
Treatment Options ◽  
Anatomical Structure ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Odontogenic Cysts ◽  
Odontogenic Keratocysts ◽  
Surgical Methods

Odontogenic Keratocyst is an aggressive odontogenic cyst with a high recurrence rate. After radicular and follicular cysts, odontogenic keratocysts are the third most common cyst of the jaws and approximately 12-14% of all odontogenic cysts. It has been retermed to Keratocystic odontogenic tumour (KCOT) as it better reflects its neoplastic nature but recently it has been re classified and retermed into the cystic category. Various surgical methods have been proposed but comparatively, conservative treatment options such as Dredging methods might be the treatment of choice due to preservation of anatomical structure. Objective: The aim of this study was to analyse the clinical, radiological and histopathological characteristics of Odontogenic Keratocyst and provide a proper management system affected by this type of lesions. Materials and methods: The prospective study was performed in Dhaka Dental College and Hospital from a period of January 2014 to January 2018. A total number of 75 patients were selected for this study based on clinical, radiological and histopathological confirmation of odontogenic keratocysts. The treatment options were enucleation, enucleation with curettage, enucleation with peripheral ostectomy, Dredging method and surgical resection. After treatment patients were followed up 1months, 3 months and 6 months in every year at least for 5 years. Results: Among 75 patient of odontogenic keratocyst; the mean age was 27.69±13.35 and age range was 11 to 66 years. Male were 53(71%) and 22 (29%) were female patients. 53 (70.67%) cases were found in the mandible, 15(20%) cases in the maxilla and in 7(9.33%) cases were involved in both maxilla and mandible; mandibular posterior region was the most specific region involved 37(69.81%).The most common clinical features revealed pain and swelling. Radiologically, 70.66% unilocular, 96% well defined and 94.66% radiolucent area were prominent. Bone expansion 37.38%, root resorption 30.00% and 36% were associated with an impacted tooth. Regarding treatment options enucleation with curatage 12%, enucleation, curettage & peripheral ostectomy 29.33%, Dredging 52% and surgical resection 6.6% was done. Recurrence occurred in 18 patients with recurrence rate of 24%. Conclusion: Odontogenic keratocyst is an aggressive cyst, male predominant, posterior mandible is the commonest site and well defined unilocular radiolucency are commonest radiological feature. Radical treatment options such as resection reduced the recurrences of the tumour but higher morbidity and jaw deformity. Comparatively, conservative treatment options such as Dredging methods might be the treatment of choice due to preservation of anatomical structure. A long term follow up is paramount importance for the research and understanding the clinical pattern, behavior, treatment and recurrence of the lesion. Update Dent. Coll. j: 2019; 9 (1): 8-15

14-Year evolution odontogenic keratocyst: Case report

2021 ◽  
Vol 62 (1) ◽  
Author(s):  
Cintia Milani ◽  
◽  
Camyla Mauricio ◽  
Luciano Francio, ◽  
Natanael Mattos ◽  
...  
Keyword(s):  
Case Report ◽  
Recurrence Rate ◽  
Bone Destruction ◽  
Good Alternative ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Standard Protocol ◽  
Recurrence Rates ◽  
Panoramic Radiographs ◽  
Carnoy’S Solution

Odontogenic keratocyst is a developmental odontogenic cyst that is usually diagnosed in routine radiographs in the early stages. This fact increases the dentist’s responsibility for its diagnosis, and the professional should pay attention to all maxillomandibular complex and not only to the teeth. There is no standard protocol for the treatment of odontogenic keratocyst. However, surgical resection is recommended because of its high recurrence rate, especially in those cases with extensive bone destruction. The enucleation followed by Carnoy’s solution application has been shown to be a good alternative to resection and pointed out as the conservative method associated with the lowest recurrence rates in the treatment of odontogenic keratocyst. This study aimed to report a case of an extensive odontogenic keratocyst with more than 14 years of evolution that had not been diagnosed in three previous different panoramic radiographs and was treated with enucleation and application of Carnoy’s solution.

scholarly journals Changes in Cellular Regulatory Factors before and after Decompression of Odontogenic Keratocysts

2020 ◽  
Vol 10 (1) ◽  
pp. 30
Author(s):  
Slmaro Park ◽  
Han-Sung Jung ◽  
Young-Soo Jung ◽  
Woong Nam ◽  
Jung Yul Cha ◽  
...  
Keyword(s):  
Recurrence Rate ◽  
Biological Behavior ◽  
Nuclear Antigen ◽  
Epithelial Cyst ◽  
Ki 67 ◽  
Proliferation Markers ◽  
Odontogenic Keratocysts ◽  
Wide Range ◽  
Before And After ◽  
Cyst Lining

Decompression followed by enucleation, which is one of the treatments used for odontogenic keratocysts (OKCs), is frequently used in OKC lesions of large sizes. This method offers the advantage of minimizing the possibility of sensory impairment without creating a wide-range bone defect; moreover, the recurrence rate can be significantly lower than following simple enucleation. This study aimed to assess the changes in histology and expression of proliferation markers in OKCs before and after decompression treatment. A total of 38 OKC tissue samples from 19 patients who had undergone decompression therapy were examined morphologically and immunohistochemically to observe changes in proliferative activity before and after decompression. The markers used for immunohistochemistry (IHC) staining were Bcl-2, epidermal growth factor receptor (EGFR), Ki-67, P53, PCNA, and SMO. The immunohistochemistry positivity of the 6 markers was scored by using software ImageJ, version 1.49, by quantifying the intensity and internal density of IHC-stained epithelium. The values of Bcl-2, Ki-67, P53, proliferating cell nuclear antigen (PCNA), and SMO in OKCs before and after decompression showed no significant change. No correlation between clinical shrinkage and morphologic changes or expression of proliferation and growth markers could be found. There was no statistical evidence that decompression treatment reduces potentially aggressive behavior of OKC within the epithelial cyst lining itself. This might indicate that decompression does not change the biological behavior of the epithelial cyst lining or the recurrence rate.

scholarly journals Retrospective Evaluation of Claw Lesions, Inflammatory Markers, and Outcome After Abomasal Rolling in Cattle with Left Displacement of the Abomasum

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1648
Author(s):  
Theresa Tschoner ◽  
Yury Zablotski ◽  
Melanie Feist
Keyword(s):  
Recurrence Rate ◽  
Surgical Procedures ◽  
Medical Records ◽  
Inflammatory Markers ◽  
Post Partum ◽  
High Recurrence Rate ◽  
Retrospective Evaluation ◽  
Analgesic Treatment ◽  
Temporary Relief ◽  
Claw Lesions

Lameness is often diagnosed in cattle with left displacement of the abomasum (LDA). Laterality of lying has an effect on the etiology of LDA, and lame cows prefer to lie on the affected limb. The objective of this study was to investigate the possible association between laterality of claw lesion and presence of LDA. The medical records of 252 cattle presented with a diagnosis of LDA and subjected to a diagnostic examination of claw lesions over a period of 11 years (2009–2019), were analyzed retrospectively. Data were evaluated for presence and localization of claw lesion, concentrations of inflammatory markers, and abomasal rolling as therapy. At least one claw lesion was diagnosed in 46.4% of cattle. There was no association between laterality of claw lesion and LDA. Presence of claw lesion or oral drench and/or analgesic treatment did not have an effect on occurrence of relapse. A high number of cattle was diagnosed with both LDA and claw lesions. Focus should lie on preventing painful claw lesions in the dry and the early post-partum period. The high recurrence rate after abomasal rolling suggests that abomasal rolling should only be considered as a therapy for temporary relief, and surgical procedures should be discussed with farmers.

scholarly journals Tratamento cirúrgico do ceratocisto odontogênico por meio de enucleação e osteotomia periférica: relato de caso

2020 ◽  
Vol 9 (6) ◽  
pp. 531-534
Author(s):  
Diogo Henrique Marques ◽  
Maylson Alves Nogueira Barros ◽  
Vitor Bruno Teslenco ◽  
Cláudio Marcio Santana Junior ◽  
Lucas Marques Meurer ◽  
...  
Keyword(s):  
Case Report ◽  
Meta Analysis ◽  
Benign Lesion ◽  
Dentigerous Cyst ◽  
Case Series ◽  
Odontogenic Keratocyst ◽  
Imaging Features ◽  
Retrospective Case ◽  
Odontogenic Keratocysts

Introdução: Os ceratocistos odontogênicos (CCA) são considerados raros cistos de desenvolvimento, derivados dos remanescentes da lâmina dentária, com atividade intraóssea benigna, porém localmente invasivo e agressivo. O tratamento para o ceratocisto odongênico é variado, podendo-se encontrar modalidades tais como:enucleação, isolada ou associada a curetagem, com osteotomia periférica, aplicação da solução de Carnoy ou crioterapia, descompressão, marsupialização e ressecções. Objetivo: O presente trabalho tem como objetivo relatar um caso de ceratocisto odontogênico, onde foi escolhida abordagem conservadora por curetagem e osteotomia periférica. Relato de caso: Paciente de 68 anos, leucoderma, referiu ao exame clínico dor espontânea em região retromolar esquerda e parestesia em lábio inferior. A paciente foi submetida a biopsia por aspiração e excisional, após confirmação histopatológica foi proposto uma enucleação associada a osteotomia periférica sob anestesia geral. A paciente permanece em acompanhamento clínico e radiográfico, sem sinais de recidiva da lesão. Conclusão: Embora apresentem um comportamento agressivo, os ceratocistos odontogêncios podem ser tratados com segurança, de forma conservadora, por meio de enucleação seguida de osteotomia periférica com mínimo de morbidade. Descritores: Osteotomia; Curetagem; Cistos Odontogênicos. Referências Borghesi A, Nardi C, Giannitto C, Tironi A, Maroldi R, Di Bartolomeo F, Preda L. Odontogenic keratocyst: imaging features of a benign lesion with an aggressive behaviour. Insights Imaging. 2018 Oct;9(5):883-897. Park JH, Kwak EJ, You KS, Jung YS, Jung HD. Volume change pattern of decompression of mandibular odontogenic keratocyst. Maxillofac Plast Reconstr Surg. 2019 Jan 7;41(1):2.  Karaca C, Dere KA, Er N, Aktas A, Tosun E, Koseoglu OT, Usubutun A. Recurrence rate of odontogenic keratocyst treated by enucleation and peripheral ostectomy: Retrospective case series with up to 12 years of follow-up. Med Oral Patol Oral Cir Bucal. 2018 Jul 1;23(4):e443-e448.  Guerra LAP, Silva PS, Dos Santos RLO, Silva AMF, Albuquerque DP. Tratamento conservador de múltiplos tumores odontogênicos ceratocístico em paciente não sindrômico. Rev cir traumatol. buco-maxilo-fac. 2013; 13(2):43-50. Sundaragiri KS, Saxena S, Sankhla B, Bhargava A. Non syndromic synchronous multiple odontogenic keratocysts in a western Indian population: A series of four cases. J Clin Exp Dent. 2018;10(8):e831-6. Freitas AD, Veloso DA, Santos ALF, Freitas VA. Maxillary odontogenic keratocyst: a clinical case report. RGO Rev Gaúch Odontol. 2015; 63(4):484-88. Madhireddy MR, Prakash AJ, Mahanthi V, Chalapathi KV. Large Follicular Odontogenic Keratocyst affecting Maxillary Sinus mimicking Dentigerous Cyst in an 8-year-old Boy: A Case Report and Review. Int J Clin Pediatr Dent. 2018 Jul-Aug;11(4):349-351.  Moura BS, Cavalcante MA, Hespanhol W. Tumor odontogênico ceratocistico. Rev Col Bras Cir., 2016;43(6):466-71. Valori FP, Costa E, Buscatti MY, Oliveira JX, Costa C. Tumor odontogênico queratocístico: características intrínsecas e elucidação da nova nomenclatura do queratocisto odontogênico. J Health Sci Inst. 2010;28(1):80-3. Slusarenko da Silva Y, Stoelinga PJW, Naclério-Homem MDG. The presentation of odontogenic keratocysts in the jaws with an emphasis on the tooth-bearing area: a systematic review and meta-analysis. Oral Maxillofac Surg. 2019;23(2):133-47.

USE OF CARNOY’S SOLUTION AS A CO-ADJUVANT IN THE TREATMENT OF ODONTOGENIC KERATOCYST

2020 ◽  
Vol 130 (3) ◽  
pp. e223
Author(s):  
ALLYSON LUCAS LIMA ◽  
ANA CARMELITA DO NASCIMENTO BASTOS ◽  
RONIELE LIMA DOS SANTOS ◽  
JESSICA EMANUELLA ROCHA PAZ ◽  
ÍCARO GIRãO EVANGELISTA ◽  
...  
Keyword(s):  
Odontogenic Keratocyst ◽  
Carnoy’S Solution

Adenomatous polyps and carcinoma in situ of the canine colon and rectum: 34 cases (1982-1994)

1997 ◽  
Vol 33 (2) ◽  
pp. 156-160 ◽  
Author(s):  
KD Valerius ◽  
BE Powers ◽  
MA McPherron ◽  
JM Hutchison ◽  
FA Mann ◽  
...  
Keyword(s):  
Malignant Transformation ◽  
Recurrence Rate ◽  
Medical Records ◽  
Carcinoma In Situ ◽  
Clinical Signs ◽  
Adenomatous Polyps ◽  
Diffuse Disease ◽  
Colon And Rectum ◽  
Mucosal Lesions

The medical records of 34 dogs (median age, eight years) with colorectal mucosal lesions were reviewed. Hematochezia was the most common (82%) presenting sign. Most dogs (79%) presented with solitary masses located in the rectum. After histological review, 12 masses were classified as adenomatous polyps and 22 as carcinoma in situ. Recurrence of clinical signs were common (41%), and malignant transformation of the tumor was documented in 18% of the cases. A higher recurrence rate and malignant transformation occurred in dogs presented with multiple masses or diffuse disease and in dogs initially diagnosed with carcinoma in situ.

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