Chromium oxidation state mapping in human cells

Redox Isomerism for Quinone Complexes of Chromium and Chromium Oxidation State Assignment from X-ray Absorption Spectroscopy

Inorganic Chemistry ◽

10.1021/ic010446w ◽

2001 ◽

Vol 40 (22) ◽

pp. 5727-5728 ◽

Cited By ~ 17

Author(s):

Cortlandt G. Pierpont

Keyword(s):

Oxidation State ◽

Absorption Spectroscopy ◽

X Ray ◽

State Assignment ◽

Redox Isomerism ◽

Chromium Oxidation ◽

X Ray Absorption ◽

Quinone Complexes

Download Full-text

An Investigation of the Chromium Oxidation State of a Monoanionic Chromium Tris(catecholate) Complex by X-ray Absorption and EPR Spectroscopies

Inorganic Chemistry ◽

10.1021/ic000298u ◽

2001 ◽

Vol 40 (2) ◽

pp. 214-217 ◽

Cited By ~ 12

Author(s):

David I. Pattison ◽

Aviva Levina ◽

Michael J. Davies ◽

Peter A. Lay

Keyword(s):

Oxidation State ◽

X Ray ◽

Catecholate Complex ◽

Chromium Oxidation ◽

X Ray Absorption

Download Full-text

Chromium Oxidation State Imaging in Mammalian Cells Exposed in Vitro to Soluble or Particulate Chromate Compounds

Chemical Research in Toxicology ◽

10.1021/tx049735y ◽

2005 ◽

Vol 18 (10) ◽

pp. 1512-1519 ◽

Cited By ~ 35

Author(s):

Richard Ortega ◽

Barbara Fayard ◽

Murielle Salomé ◽

Guillaume Devès ◽

Jean Susini

Keyword(s):

Oxidation State ◽

Mammalian Cells ◽

Chromium Oxidation

Download Full-text

Determination of chromium oxidation state by X-ray fluorescence spectrometry: application to chromium(VI) and chromium(III) determination in occupational hygiene samples

The Analyst ◽

10.1039/an9881300779 ◽

1988 ◽

Vol 113 (5) ◽

pp. 779 ◽

Cited By ~ 17

Author(s):

Judith M. Arber ◽

David S. Urch ◽

Norman G. West

Keyword(s):

Oxidation State ◽

Fluorescence Spectrometry ◽

Occupational Hygiene ◽

X Ray ◽

Chromium Vi ◽

Chromium Oxidation

Download Full-text

Determination of Chromium Oxidation State in Cultures of Dissimilatory Metal Reducing Bacteria by Electron Energy Loss Spectroscopy

Microscopy and Microanalysis ◽

10.1017/s1431927603447405 ◽

2003 ◽

Vol 9 (S02) ◽

pp. 1480-1481 ◽

Cited By ~ 5

Author(s):

Tyrone L. Daulton ◽

Brenda J. Little ◽

Kristine Lowe

Keyword(s):

Energy Loss ◽

Electron Energy ◽

Oxidation State ◽

Electron Energy Loss Spectroscopy ◽

Chromium Oxidation ◽

Reducing Bacteria ◽

Electron Energy Loss ◽

Metal Reducing Bacteria

Download Full-text

Hydrogen Peroxide Effects on Chromium Oxidation State and Solubility in Four Diverse, Chromium-Enriched Soils

Environmental Science & Technology ◽

10.1021/es010597y ◽

2001 ◽

Vol 35 (20) ◽

pp. 4054-4059 ◽

Cited By ~ 37

Author(s):

Melanie L. Rock ◽

Bruce R. James ◽

George R. Helz

Keyword(s):

Hydrogen Peroxide ◽

Oxidation State ◽

Chromium Oxidation

Download Full-text

Alpha-Tocopherol Protects Cultured Human Cells from the Acute Lethal Cytotoxicity of Dioxin

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831.72.3.147 ◽

2002 ◽

Vol 72 (3) ◽

pp. 147-153 ◽

Cited By ~ 8

Author(s):

Kei-Ichi Hirai ◽

Jie-Hong Pan ◽

Ying-Bo Shui ◽

Eriko Simamura ◽

Hiroki Shimada ◽

...

Keyword(s):

Cell Death ◽

Cell Damage ◽

Smooth Endoplasmic Reticulum ◽

Dehydroascorbic Acid ◽

Human Cells ◽

Alpha Tocopherol ◽

Cervical Cancer Cells ◽

Cultured Human Cells ◽

Nuclear Damage ◽

Conjunctival Epithelial Cells

The possible protection of cultured human cells from acute dioxin injury by antioxidants was investigated. The most potent dioxin, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), caused vacuolization of the smooth endoplasmic reticulum and Golgi apparatus in cultured human conjunctival epithelial cells and cervical cancer cells. Subsequent nuclear damage included a deep irregular indentation resulting in cell death. A dosage of 30–40 ng/mL TCDD induced maximal intracellular production of H2O2 at 30 minutes and led to severe cell death (0–31% survival) at two hours. A dose of 1.7 mM alpha-tocopherol or 1 mM L-dehydroascorbic acid significantly protected human cells against acute TCDD injuries (78–97% survivals), but vitamin C did not provide this protection. These results indicate that accidental exposure to fatal doses of TCDD causes cytoplasmic free radical production within the smooth endoplasmic reticular systems, resulting in severe cytotoxicity, and that vitamin E and dehydroascorbic acid can protect against TCDD-induced cell damage.

Download Full-text