scholarly journals Development of an effective way to increase the biological activity of nicotinamide – a new strategy to protect against photoageing and skin neoplasia

2020 ◽  
Vol 22 ◽  
pp. 01005
Author(s):  
Elena Uspenskaya ◽  
Tatyana Pleteneva ◽  
Anton Syroeshkin ◽  
Ilaha Kasymova ◽  
Nataliya Zakharova
Keyword(s):  
Biological Activity ◽  
Mechanical Activation ◽  
Order Rate Constant ◽  
Biological Properties ◽  
High Rate ◽  
Optical Methods ◽  
Dead Cell ◽  
Physical Chemical ◽  
New Strategy ◽  
Spirostomum Ambiguum

The objective of this work is to demonstrate changes in properties and increase of biological activity of nicotinamide (NAM) substance for skin protectants activated by mechanical activation (MA). To assess the physical, chemical and biological properties of NAM were used biotesting by the Spirotox-method, direct and indirect optical methods (microscopy, laser diffraction), infrared spectroscopy, pH-metry. The results of the study showed an increase in biological activity, expressed in changes in the energy of activation of cell transition to the “dead cell” state on the example of biosensor Spirostomum ambiguum. Also we indicated an increase in the rate of the chemical process of dissolution of mechanoactivated molecular crystals of nicotinamide (NAM) expressed in the values of the first order rate constant. Mechanical activation at a high rate of NAM substance powder deformation has led to changes in physical, chemical and biological properties of the drug, which can be used in medicine to increase efficiency and reduce doses of pharmacotherapy.

Biological Function and Chemistry of Endothelin. A Review

1999 ◽  
Vol 64 (8) ◽  
pp. 1211-1252 ◽  
Author(s):  
Jan Hlaváček ◽  
Renáta Marcová
Keyword(s):  
Biological Activity ◽  
Amino Acid ◽  
Biological Function ◽  
Biological Properties ◽  
Structural Basis ◽  
Amino Acid Residues ◽  
Snake Venoms ◽  
Vasoactive Peptides ◽  
Physico Chemical ◽  
Endothelin A

The first part of this review deals with the biosynthesis and a biological function of strongly vasoactive peptides named endothelins (ETs) including vasoactive intestinal contractor. Where it was useful, snake venoms sarafotoxins which are structural endothelin derivatives, were also mentioned. In the second part, an attention is paid to structural basis of the ETs biological activity, with respect to alterations of amino acid residues in the parent peptides modifying the conformation and consequently the physico-chemical and biological properties in corresponding ETs analogs. Special attention is focussed on the area of ETs receptors and their interaction with peptide and non peptide agonists and antagonists, important in designing selective inhibitors of ETs receptors potentially applicable as drugs in a medicine. A review with 182 references.

scholarly journals Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide

2001 ◽  
Vol 42 (7) ◽  
pp. 1096-1104 ◽  
Author(s):  
Geeta Datta ◽  
Manjula Chaddha ◽  
Susan Hama ◽  
Mohamad Navab ◽  
Alan M. Fogelman ◽  
...  
Keyword(s):  
Biological Properties ◽  
Class A ◽  
Physical Chemical ◽  
Helical Peptide

Nanobiotechnology: Nature-inspired silver nanoparticles towards green synthesis

2021 ◽  
pp. 0958305X2198988
Author(s):  
Nur Syakirah Rabiha Rosman ◽  
Noor Aniza Harun ◽  
Izwandy Idris ◽  
Wan Iryani Wan Ismail
Keyword(s):  
Electrical Conductivity ◽  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Metal Nanoparticles ◽  
Current Trend ◽  
Biological Properties ◽  
Noble Metal Nanoparticles ◽  
Current Application ◽  
Physical Chemical ◽  
Physical And Chemical

The emergence of technology to produce nanoparticles (1 nm – 100 nm in size) has drawn significant researchers’ interests. Nanoparticles can boost the antimicrobial, catalytic, optical, and electrical conductivity properties, which cannot be achieved by their corresponding bulk. Among other noble metal nanoparticles, silver nanoparticles (AgNPs) have attained a special emphasis in the industry due to their superior physical, chemical, and biological properties, closely linked to their shapes, sizes, and morphologies. Proper knowledge of these NPs is essential to maximise the potential of biosynthesised AgNPs in various applications while mitigating risks to humans and the environment. This paper aims to critically review the global consumption of AgNPs and compare the AgNPs synthesis between conventional methods (physical and chemical) and current trend method (biological). Related work, advantages, and drawbacks are also highlighted. Pertinently, this review extensively discusses the current application of AgNPs in various fields. Lastly, the challenges and prospects of biosynthesised AgNPs, including application safety, oxidation, and stability, commercialisation, and sustainability of resources towards a green environment, were discussed.

scholarly journals Effect of Lignite Fly Ash on the Growth and Reproduction of Earthworm Eisenia fetida

2009 ◽  
Vol 6 (2) ◽  
pp. 511-517 ◽  
Author(s):  
S. Sarojini ◽  
S. Ananthakrishnasamy ◽  
G. Manimegala ◽  
M. Prakash ◽  
G. Gunasekaran
Keyword(s):  
Fly Ash ◽  
Eisenia Fetida ◽  
Power Plants ◽  
Thermal Power ◽  
Biological Properties ◽  
Cow Dung ◽  
Physical Chemical ◽  
Lignite Fly Ash ◽  
Agricultural Use ◽  
Growth And Reproduction

Fly ash is an amorphous ferroalumino silicate, an important solid waste around thermal power plants. It creates problems leading to environmental degradation due to improper utilization or disposal. However, fly ash is a useful ameliorant that may improve the physical, chemical and biological properties of soils and is a source of readily available plant macro and micronutrients when it is used with biosolids. Supply of nutrients from fly ash with biosolids may enhance their agricultural use. The growth and reproduction ofEisenia fetidawas studied during vermicomposting of fly ash with cowdung and pressmud in four different proportions (T1,T2,T3& T4) and one controli.e.,cow dung and pressmud alone. The growth, cocoon and hatchlings production were observed at the interval of 15 days over a period of 60 days. The maximum worm growth and reproduction was observed in bedding material alone. Next to that the T1was observed as the best mixture for vermiculture.

scholarly journals Micro: An International Open Access Journal for All of Microscale and Nanoscale Science

Micro ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 1-2
Author(s):  
Eiichi Tamiya
Keyword(s):  
Open Access ◽  
20Th Century ◽  
Special Interest ◽  
Biological Properties ◽  
Open Access Journal ◽  
Length Scale ◽  
Late 20Th Century ◽  
Physical Chemical ◽  
Nanoscale Science

Since the late 20th century, there has been a special interest in the microscale and nanoscale research investigating and exploiting the physical, chemical, and biological properties of these length-scale systems [...]

Aktywność biologiczna ekstraktów z propolisu

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Magdalena Woźniak ◽  
Anna Kwiatkowska ◽  
Elżbieta Hołderna-Kędzia ◽  
Katarzyna Sosnowska ◽  
Lucyna Mrówczyńska ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Biological Activity ◽  
Phenolic Compounds ◽  
Propylene Glycol ◽  
Ethyl Alcohol ◽  
Antiradical Activity ◽  
Colorimetric Method ◽  
Biological Properties ◽  
Bioactive Substances ◽  
Dpph Test

Introduction. Propolis, also known as bee glue, is a resinous material collected by honeybees with numerous biological properties, including antibacterial, antifungal, antioxidant and anticancer effects. Due to its health-promoting properties, propolis is a component of many products, including dietary supplements, cosmetics and healthy food. Aim. The aim of the study was to determine the antibacterial, antifungal and antioxidant activity of propolis extracts, as well as to compare the biological activity of propolis extracts, depending on the solvent used – ethyl alcohol or propylene glycol. Material and methods. Two propolis extracts were used in the research – the first was prepared in ethyl alcohol, and the second in propylene glycol. The antimicrobial activity of the examined extracts was determined against S. aureus, E. coli and C. albicans. The antioxidant activity was determined on the basis of the evaluation of their antiradical activity in the DPPH· test and Fe2+ chelating activity. Moreover, the total content of phenolic compounds and flavonoids in the tested extracts was determined using the colorimetric method. Results. The tested propolis extracts, regardless of the solvent used (ethyl alcohol or propylene glycol), showed high antibacterial (against S. aureus), antifungal (against C. albicans) and antioxidant (antiradical activity in the DPPH· test and ferrous iron chelating potency in the ferrozine test) activity. Moreover, both tested extracts were characterized by a high and similar content of bioactive compounds – phenolic compounds and flavonoids. Conclusions. The results of the conducted tests showed that the solvent used did not affect determined biological activity and the content of bioactive substances in the tested propolis extracts.

Assessment of Seasonal and Site-Specific Variations in Soil Physical, Chemical and Biological Properties Around Opencast Coal Mines

Pedosphere ◽  
2019 ◽  
Vol 29 (5) ◽  
pp. 642-655 ◽  
Author(s):  
Bhanu PANDEY ◽  
Arideep MUKHERJEE ◽  
Madhoolika AGRAWAL ◽  
Siddharth SINGH
Keyword(s):  
Coal Mines ◽  
Biological Properties ◽  
Site Specific ◽  
Physical Chemical ◽  
Opencast Coal Mines

Synthesis, characterization and biological properties of new hybrid carbosilane–viologen–phosphorus dendrimers

RSC Advances ◽  
2015 ◽  
Vol 5 (33) ◽  
pp. 25942-25958 ◽  
Author(s):  
Silvia Moreno ◽  
Aleksandra Szwed ◽  
Nabil El Brahmi ◽  
Katarzyna Milowska ◽  
Joanna Kurowska ◽  
...  
Keyword(s):  
Biological Properties ◽  
Onion Peel ◽  
Physical Chemical

Hybrid carbosilane–viologen–phosphorus dendrimers were prepared, as an example of the synthetic “onion peel” approach, on the search of new physical–chemical and biological properties, respecting traditional dendritic architectures.

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