scholarly journals Development and characterisation of glucosamine sulphate magnetic nanoparticles for rheumatoid arthritis chemotherapy

2020 ◽  
Vol 15 (13) ◽  
pp. 954-958
Author(s):  
Latha Subbiah ◽  
Selvamani Palanisamy ◽  
Deepak B. Thimiri Govinda Raj
Keyword(s):  
Rheumatoid Arthritis ◽  
Magnetic Nanoparticles ◽  
Glucosamine Sulphate

Magnetic nanoparticles are widely used in drug delivery, imaging, diagnosis, and targeting. It has promises for the treatment of inflammatory disorders such as rheumatoid arthritis

2021 ◽  
Author(s):  
Moataz Dowaidar
Keyword(s):  
Rheumatoid Arthritis ◽  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Joint Damage ◽  
Imaging Diagnosis ◽  
New Era ◽  
Inflammatory Disorders ◽  
Persistent Inflammation ◽  
Precision Therapy ◽  
The Times

Rheumatoid arthritis (RA) is an autoimmune disease that causes persistent inflammation and joint damage. Traditional medications like methotrexate, leflunomide, and antimalarials, as well as novel biological medicines like adalimumab, etanercept, and infliximab, make up the DMARDs. New medications, such as upadacitinib17, a specific JAK-1 inhibitor, and rituximab have recently been introduced to the RA treatment arsenal. Nanoparticles are able to travel across loose vasculature and penetrate into inflammatory areas and tumor sites due to their unique physical features. The application of MNPs in the treatment, diagnosis, and targeting of rheumatoid arthritis is the topic of this review.Nanotechnology is a subset of nanomaterials that are widely used in drug delivery, imaging, diagnosis, and targeting.It has been used to treat malignancies and, more recently, the treatment of inflammatory disorders such as rheumatoid arthritis. The findings have motivated scientists to test MNPs in a variety of disorders. While research into magnetically focused treatment and diagnostics is still in its early phases, it has already shown great potential. MNP technologies confront a number of challenges, including not just overcoming their inherent weaknesses, but also keeping up with the times. Using a single-cell method, the diversity of synovial cells and immune cells in joints was discovered. Precision therapy necessitates the application of MNP technology to further target specific cells. Because of the efficacy of exosomes in treating RA, bio-membrane encapsulated MNPs have been developed. Furthermore, the discovery of MNPs' effects on cell autophagy and metabolism has ushered in a new era in the mechanistic research of magnetic nanoparticles. Overall, magnetic nanoparticle modification is a promising platform for treating rheumatoid arthritis that is both promising and challenging.

Macrophages mediated diagnosis of rheumatoid arthritis using fibrin based magnetic nanoparticles as MRI contrast agents

2017 ◽  
Vol 1861 (1) ◽  
pp. 2992-3001 ◽  
Author(s):  
Prabu Periyathambi ◽  
Thotapalli Parvathaleswara Sastry ◽  
Suresh Kumar Anandasadagopan ◽  
Kanagavel Manickavasagam
Keyword(s):  
Rheumatoid Arthritis ◽  
Magnetic Nanoparticles ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Mri Contrast

Magnetic nanoparticles: A new diagnostic and treatment platform for rheumatoid arthritis

2020 ◽  
Author(s):  
Yan Liu ◽  
Fenglin Cao ◽  
Baoqing Sun ◽  
Joseph A. Bellanti ◽  
Song Guo Zheng
Keyword(s):  
Rheumatoid Arthritis ◽  
Magnetic Nanoparticles

Effect of magnetic nanoparticles size on rheumatoid arthritis targeting and photothermal therapy

2018 ◽  
Vol 170 ◽  
pp. 224-232 ◽  
Author(s):  
Shengchang Zhang ◽  
Lin Wu ◽  
Jin Cao ◽  
Kaili Wang ◽  
Yanru Ge ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Magnetic Nanoparticles ◽  
Photothermal Therapy

Association of vitamin D receptor genotypes with early onset rheumatoid arthritis

2001 ◽  
Vol 28 (1) ◽  
pp. 89-93 ◽  
Author(s):  
J. R. Garcia-Lozano ◽  
M. F. Gonzalez-Escribano ◽  
A. Valenzuela ◽  
A. Garcia ◽  
A. Nunez-Roldan
Keyword(s):  
Rheumatoid Arthritis ◽  
Vitamin D ◽  
Vitamin D Receptor ◽  
Early Onset
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