Mind to market - why and how biomedical charities today fund medical technologies for the future

2007 ◽  
Author(s):  
R. Seabrook
Keyword(s):  
Medical Technologies ◽  
The Future

New medical technologies of the future

2013 ◽  
Author(s):  
Georgi Graschew ◽  
Stefan Rakowsky ◽  
Theo A. Roelofs ◽  
Peter M. Schlag
Keyword(s):  
Medical Technologies ◽  
The Future

scholarly journals The impact of medical technologies on the future of hospitals

BMJ ◽  
1999 ◽  
Vol 319 (7220) ◽  
pp. 1287-1287 ◽  
Author(s):  
C. B Wilson
Keyword(s):  
Medical Technologies ◽  
The Future ◽  
The Impact

PROBLEMS OF AUTOIMMUNITY AND AUTOINFLAMMATION IN RHEUMATOLOGY: LESSONS FROM CORONAVIRUS DISEASE 2019 (COVID-19)

2021 ◽  
Vol 100 (2) ◽  
pp. 12-17
Author(s):  
E.L. Nasonov ◽  
◽  
Keyword(s):  
Rheumatic Diseases ◽  
Inflammatory Diseases ◽  
Drug Repurposing ◽  
Treatment Methods ◽  
Medical Technologies ◽  
The Future ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
New Treatment ◽  
Diagnostic Capabilities

According to modern concepts, human immuno-inflammatory diseases, depending on the prevailing mechanisms of immunity activation, are divided into two main categories: autoimmune and auto-inflammatory, related to the activation of acquired and congenital immunity respectively. Autoimmunity and autoinflammation are particularly prevalent in immunoinflammatory rheumatic diseases (IMRD), deciphering of the pathogenesis, expanding diagnostic capabilities and developing new treatment methods are among the priorities of medicine in the XXI century. The development of various immunopatological disorders, that determine the prognosis in patients with COVID-19 served as the basis for the drug repurposing of anti-inflammatory drugs previously specially developed for the treatment of IMRD. This is a vivid example of the demand for new medical technologies for the treatment not only of IMRD, but also of COVID-19 and, in the future, of other virus-induced immune diseases.

scholarly journals The future of meniscus science: international expert consensus

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Nicholas N. DePhillipo ◽  
Robert F. LaPrade ◽  
Stefano Zaffagnini ◽  
Caroline Mouton ◽  
Romain Seil ◽  
...  
Keyword(s):  
Research And Development ◽  
Clinical Outcomes ◽  
Platelet Rich Plasma ◽  
Meniscus Repair ◽  
Expert Consensus ◽  
Future Research ◽  
Level Of Evidence ◽  
Medical Technologies ◽  
The Future

Abstract Purpose The purpose of this study was to evaluate the main focus areas for research and development for furthering the state of meniscus science in 2021. Methods An electronic survey including 10 questions was sent in a blind fashion to the faculty members of the 5th International Conference on Meniscus Science and Surgery. These faculty served as an expert consensus on the future of research and development areas of meniscus science. Survey responses were analyzed using descriptive statistics and ranking weighted averages were calculated to score survey questions. Results Of the 82 faculty, 76 (93%) from 18 different countries completed the survey (84% male, 16% female). The highest ranked future research and development focus areas were meniscus repair, biologics, osteotomy procedures, addressing meniscus extrusion, and the development of new therapies for the prevention of posttraumatic osteoarthritis. Currently, the most ‘valuable’ type of biologic reported for meniscus treatment was platelet-rich plasma. The main reported global research limitation was a lack of long-term clinical outcomes data. The most promising emerging medical technologies for improving meniscus science were 3-D printing, personalized medicine, and artificial implants. Conclusions This survey suggests that the future of meniscus science should be focused on meniscal preservation techniques through meniscus repair, addressing meniscal extrusion, and the use of orthobiologics. The lack of long-term clinical outcomes was the main reported research limitation globally for meniscus treatment. Future product development utilizing emerging medical technologies suggest the use of 3-D printing for meniscal transplants/scaffolds, personalized treatment, and bioengineering for artificial implants. Level of Evidence Level V.

International determination of the total motion of the pole

1961 ◽  
Vol 13 ◽  
pp. 29-41
Author(s):  
Wm. Markowitz
Keyword(s):  
Secular Motion ◽  
The Future

A symposium on the future of the International Latitude Service (I. L. S.) is to be held in Helsinki in July 1960. My report for the symposium consists of two parts. Part I, denoded (Mk I) was published [1] earlier in 1960 under the title “Latitude and Longitude, and the Secular Motion of the Pole”. Part II is the present paper, denoded (Mk II).

Status of the Lick Proper Motion Program

1978 ◽  
Vol 48 ◽  
pp. 387-388
Author(s):  
A. R. Klemola
Keyword(s):  
Proper Motion ◽  
The Future

Second-epoch photographs have now been obtained for nearly 850 of the 1246 fields of the proper motion program with centers at declination -20° and northwards. For the sky at 0° and northward only 130 fields remain to be taken in the next year or two. The 270 southern fields with centers at -5° to -20° remain for the future.

Some Structural Features of Metaphase Chromosomes of Mice and Men

1967 ◽  
Vol 25 ◽  
pp. 190-191
Author(s):  
Godfrey C. Hoskins ◽  
Betty B. Hoskins
Keyword(s):  
Electron Microscopy ◽  
Electron Micrographs ◽  
Structural Features ◽  
Metaphase Chromosomes ◽  
The Future ◽  
Of Mice And Men ◽  
Mouse Cells ◽  
Human And Mouse

Metaphase chromosomes from human and mouse cells in vitro are isolated by micrurgy, fixed, and placed on grids for electron microscopy. Interpretations of electron micrographs by current methods indicate the following structural features.Chromosomal spindle fibrils about 200Å thick form fascicles about 600Å thick, wrapped by dense spiraling fibrils (DSF) less than 100Å thick as they near the kinomere. Such a fascicle joins the future daughter kinomere of each metaphase chromatid with those of adjacent non-homologous chromatids to either side. Thus, four fascicles (SF, 1-4) attach to each metaphase kinomere (K). It is thought that fascicles extend from the kinomere poleward, fray out to let chromosomal fibrils act as traction fibrils against polar fibrils, then regroup to join the adjacent kinomere.

Freeze-fracture cytochemistry: A goal set by Russell Steere in 1957

1993 ◽  
Vol 51 ◽  
pp. 60-61
Author(s):  
Nicholas J Severs
Keyword(s):  
Chemical Nature ◽  
Biological Systems ◽  
Freeze Fracture ◽  
Structural Components ◽  
Major Goal ◽  
Membrane Biology ◽  
Routine Application ◽  
The Future ◽  
Freeze Etching

In his pioneering demonstration of the potential of freeze-etching in biological systems, Russell Steere assessed the future promise and limitations of the technique with remarkable foresight. Item 2 in his list of inherent difficulties as they then stood stated “The chemical nature of the objects seen in the replica cannot be determined”. This defined a major goal for practitioners of freeze-fracture which, for more than a decade, seemed unattainable. It was not until the introduction of the label-fracture-etch technique in the early 1970s that the mould was broken, and not until the following decade that the full scope of modern freeze-fracture cytochemistry took shape. The culmination of these developments in the 1990s now equips the researcher with a set of effective techniques for routine application in cell and membrane biology.Freeze-fracture cytochemical techniques are all designed to provide information on the chemical nature of structural components revealed by freeze-fracture, but differ in how this is achieved, in precisely what type of information is obtained, and in which types of specimen can be studied.

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