Refractive index change induced by ultraviolet laser irradiations in erbium-doped tellurite glasses

2003 ◽  
Vol 39 (22) ◽  
pp. 1576 ◽  
Author(s):  
T. Fujiwara ◽  
T. Nakamoto ◽  
T. Honma ◽  
Y. Benino ◽  
T. Komatsu
Keyword(s):  
Refractive Index ◽  
Refractive Index Change ◽  
Tellurite Glasses ◽  
Index Change ◽  
Ultraviolet Laser ◽  
Erbium Doped

Vacuum-ultraviolet laser-induced refractive index change of fused silica

1998 ◽  
Vol 127-129 ◽  
pp. 843-847 ◽  
Author(s):  
Koji Sugioka ◽  
Jie Zhang ◽  
Schlomo Ruschin ◽  
Satoshi Wada ◽  
Hideo Tashiro ◽  
...  
Keyword(s):  
Refractive Index ◽  
Vacuum Ultraviolet ◽  
Refractive Index Change ◽  
Fused Silica ◽  
Index Change ◽  
Ultraviolet Laser ◽  
Vacuum Ultraviolet Laser

scholarly journals Critical angle reflection imaging for quantification of molecular interactions on glass surface

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Guangzhong Ma ◽  
Runli Liang ◽  
Zijian Wan ◽  
Shaopeng Wang
Keyword(s):  
Refractive Index ◽  
Small Molecule ◽  
Molecular Interactions ◽  
Glass Surface ◽  
Critical Angle ◽  
Dynamic Range ◽  
Refractive Index Change ◽  
Label Free ◽  
Index Change ◽  
Sensing Range

AbstractQuantification of molecular interactions on a surface is typically achieved via label-free techniques such as surface plasmon resonance (SPR). The sensitivity of SPR originates from the characteristic that the SPR angle is sensitive to the surface refractive index change. Analogously, in another interfacial optical phenomenon, total internal reflection, the critical angle is also refractive index dependent. Therefore, surface refractive index change can also be quantified by measuring the reflectivity near the critical angle. Based on this concept, we develop a method called critical angle reflection (CAR) imaging to quantify molecular interactions on glass surface. CAR imaging can be performed on SPR imaging setups. Through a side-by-side comparison, we show that CAR is capable of most molecular interaction measurements that SPR performs, including proteins, nucleic acids and cell-based detections. In addition, we show that CAR can detect small molecule bindings and intracellular signals beyond SPR sensing range. CAR exhibits several distinct characteristics, including tunable sensitivity and dynamic range, deeper vertical sensing range, fluorescence compatibility, broader wavelength and polarization of light selection, and glass surface chemistry. We anticipate CAR can expand SPR′s capability in small molecule detection, whole cell-based detection, simultaneous fluorescence imaging, and broader conjugation chemistry.

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