Research of the method of reconstructing the repair bionic scaffold based on tissue engineering

2006 ◽  
Author(s):  
Lin Liulan ◽  
Liu Hanqing ◽  
Hu Qingxi ◽  
Li Limin ◽  
Fang Minglun
Keyword(s):  
Tissue Engineering ◽  
Bionic Scaffold

Biological properties of a bionic scaffold for esophageal tissue engineering research

2019 ◽  
Vol 179 ◽  
pp. 208-217 ◽  
Author(s):  
Ruixia Hou ◽  
Xingyuan Wang ◽  
Qianqian Wei ◽  
Peipei Feng ◽  
Xianbo Mou ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Biological Properties ◽  
Engineering Research ◽  
Bionic Scaffold ◽  
Esophageal Tissue ◽  
Tissue Engineering Research

Finite Element Analysis of the Bionic Tissue Engineering Scaffold for the Defect Cranium

2012 ◽  
Vol 184-185 ◽  
pp. 222-226
Author(s):  
Fan Fen Peng ◽  
Shu Xian Zheng ◽  
Jia Li
Keyword(s):  
Mechanical Properties ◽  
Mechanical Property ◽  
Tissue Engineering ◽  
Finite Element Analysis ◽  
Tissue Engineering Scaffold ◽  
Element Analysis ◽  
Engineering Technology ◽  
Bionic Scaffold ◽  
Bottle Neck ◽  
The Relationship

The relationship between the porosity and the mechanical property was still a bottle-neck in bone tissue engineering scaffold. Porosity increasing may reduce the scaffold strength. In order to solve the contradiction, the idea of enhancing the mechanical properties by controlling the scaffold porosity was proposed in this paper. Using reverse engineering technology, 5 different porosity cranium scaffolds were first established. Their FE models were built through FE surface preprocessing and volume fitted meshing. According to results of static analysis, the displacements and stresses of the 5 porosity scaffolds were compared and discussed and it indicated that the 36% porosity bionic scaffold have good porous level and mechanical properties.

Decellularized bone extracellular matrix in skeletal tissue engineering

2020 ◽  
Vol 48 (3) ◽  
pp. 755-764
Author(s):  
Benjamin B. Rothrauff ◽  
Rocky S. Tuan
Keyword(s):  
Tissue Engineering ◽  
Bone Regeneration ◽  
Tissue Regeneration ◽  
Animal Studies ◽  
Tumor Resection ◽  
Regenerative Capacity ◽  
Skeletal Tissue ◽  
Large Bone

Bone possesses an intrinsic regenerative capacity, which can be compromised by aging, disease, trauma, and iatrogenesis (e.g. tumor resection, pharmacological). At present, autografts and allografts are the principal biological treatments available to replace large bone segments, but both entail several limitations that reduce wider use and consistent success. The use of decellularized extracellular matrices (ECM), often derived from xenogeneic sources, has been shown to favorably influence the immune response to injury and promote site-appropriate tissue regeneration. Decellularized bone ECM (dbECM), utilized in several forms — whole organ, particles, hydrogels — has shown promise in both in vitro and in vivo animal studies to promote osteogenic differentiation of stem/progenitor cells and enhance bone regeneration. However, dbECM has yet to be investigated in clinical studies, which are needed to determine the relative efficacy of this emerging biomaterial as compared with established treatments. This mini-review highlights the recent exploration of dbECM as a biomaterial for skeletal tissue engineering and considers modifications on its future use to more consistently promote bone regeneration.

Combination of MRI and 99mTc-NTP 15-5 Scintigraphy for the Assessment of Intervertebral Disk Degeneration and Tissue Engineering

2012 ◽  
Vol 2 (1_suppl) ◽  
pp. s-0032-1319873-s-0032-1319873
Author(s):  
P. Colombier ◽  
J. Clouet ◽  
E. Miot-Noirault ◽  
A. Vidal ◽  
F. Cachin ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Intervertebral Disk ◽  
Intervertebral Disk Degeneration ◽  
Disk Degeneration
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